Clinical trials: Recovery of Postoperative
Total Hip Arthroplasty
Efficacy of Intravenous Oxytocin to Speed Recovery After THA
The purpose of this study is to test whether perioperative intravenous (IV) oxytocin compared to placebo results in faster recovery in disability as measured by daily steps over 56 days after Total Hip Arthroplasty (THA).
- Trial name
- NCT07430228
- Testing
- intravenous administration of oxytocin
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Morbid Obesity, PCA
Dual-chamber Patient-controlled Analgesia for Postoperative Recovery
Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV.
- Conditions
- Morbid Obesity, PCA, Analgesia, PONV
- Trial name
- NCT07051109
- Testing
- multimodal analgesia via dual-chamber PCA, single regimen (only fentanyl)
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Bundang Hospital
Recovery of Function
Cross-cultural Adaptation and Validation in Moroccan Arabic Dialect "Darija" of the QoR-15 Postoperative Recovery Quality Score"
The QoR-15 Is a post operative recovery score developed in 2013 from the QoR-40 with an advantage of simplification. The investigators Aim to translate and to validate a such useful score in Arabic adapted for Morocco by a full…
- Trial name
- NCT04607577
- Where
- Morocco
- Volunteers
- 200 people
- Sponsor
- Moroccan Society of Surgery
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs in DCD Kidney Transplantation
This study is designed to determine the efficacy and safety of allogeneic bone marrow-derived mesenchymal stem cells in kidney transplantation from Chinese donation after citizen's death (DCD).
- Trial name
- NCT02561767
- Testing
- bone marrow-derived mesenchymal stem cells, Saline, Induction therapy (ATG or Basiliximab)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Supplemental Oxygen, Gynecological Cancer
Supplemental High Flow Oxygen to Reduce Infections in Obese Gynecological Cancer Patients
The incidence of surgical-site infection (SSI) and complications related to wound healing reaches 10-20% of gynecological cancer patients.
- Conditions
- Supplemental Oxygen, Gynecological Cancer, Surgical Site Infections
- Trial name
- SAFE (NCT06780813)
- Testing
- Supplemental oxygen therapy
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- National and Kapodistrian University of Athens
Carpal Tunnel Syndrome
A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common condition that causes numbness, tingling, pain, and weakness in the hand due to compression of the median nerve at the wrist.
- Trial name
- NCT07312123
- Testing
- Alpha-Lipoic Acid, Vitamin E, and Vitamin B Complex, Combination Vitamin B1,B6,B12
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- Hospital Universiti Sains Malaysia
Head and Neck Carcinoma
An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery
This clinical trial evaluates a prehabilitation exercise intervention for improving mobility and recovery outcomes in patients undergoing surgery for head and neck cancer.
- Trial name
- NCT06079697
- Testing
- Electronic Health Record Review, Exercise Intervention, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- OHSU Knight Cancer Institute
Postoperative Cognitive Decline, Biomarkers
Patients Experiences of Early Postoperative Cognition
The study has a mixed-methods design i.e. integration of qualitative and quantitative data within a single investigation. Participants included will be patients ≥60 years that are undergoing major elective joint replacement…
- Conditions
- Postoperative Cognitive Decline, Biomarkers, Postoperative Recovery, Joint Replacement Surgery
- Trial name
- COME (NCT05361460)
- Testing
- Cognitive decline
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Laryngeal Disease, Pharyngeal Diseases
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.
- Conditions
- Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease
- Trial name
- NCT06507202
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Cancer Survivor, Depression
Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer
RATIONALE: Telephone counseling after radical prostatectomy may help African American prostate cancer survivors and their intimate partners cope with the problems and challenges of surgery, and may reduce distress and improve…
- Conditions
- Cancer Survivor, Depression, Gastrointestinal Complications, Male Erectile Disorder
- Trial name
- NCT00869739
- Testing
- telephone-based intervention, educational intervention, partner-assisted coping skills training
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Total Knee Arthroplasty, Regional Anesthesia
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen following primary total knee…
- Conditions
- Total Knee Arthroplasty, Regional Anesthesia, Multimodal Analgesic Approach, Postoperative Opioid-related Complications
- Trial name
- NCT06908837
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Regionshospitalet Silkeborg
Breast Cancer, Postoperative Pain, Acute
Effect of Continuous Erector Spinae Plane Block With Ropivacaine on Postoperative Pain and NF-κB Levels After Mastectomy
This study aims to evaluate the effect of continuous erector spinae plane block (CESPB) using ropivacaine on postoperative pain in patients undergoing elective mastectomy.
- Trial name
- NCT07562945
- Testing
- Continuous Erector Spinae Plane Block, Ropivacaine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Aldy Aldy
Postoperative Complications
4-choice Reaction Time Test for the Measurement of Psychomotor Recovery After General Anaesthesia
The recovery of patients after general anaesthesia is usually estimated by using clinical signs and scores. Since there is a lack of the agreed objective methods for assessing cognitive and psychomotor recovery after general…
- Trial name
- 4CRT_Ane (NCT03697057)
- Testing
- General anaesthesia
- Where
- Germany
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Postoperative Pain, Quality of Recovery (QoR-15)
MAG-PAIN - MAGnesium for Postoperative Analgesia In the Newly Delivered
The study aims to investigate whether a commonly used medicine, magnesium, can help reduce pain after a Caesarean section. A total of 150 participants will be included.
- Conditions
- Postoperative Pain, Quality of Recovery (QoR-15), Pain Prediction, Magnesium Sulfate
- Trial name
- MAG-PAIN (NCT07528612)
- Testing
- Magnesium group
- Volunteers
- 150 people
- Sponsor
- Region Halland
Hip Fracture Surgeries, Post-operative Hip Fractures Recovery
ACUPUNCTURE FOR THE POSTOPERATIVE RECOVERY OF HIP FRACTURE PATIENTS: A PILOT RANDOMIZED CONTROLLED TRIAL
Hip surgery is a common and safe medical intervention to restore the functionality and mobility of the hip joint in patients suffering from hip fractures.
- Trial name
- AFTPROHFP (NCT07178756)
- Testing
- Acupuncture, Post-operative standard care
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- Khoo Teck Puat Hospital
Bone Neoplasm, Rehabilitation
Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.
The aim of the present study is to describe the course of functional recovery of patients with musculoskeletal tumours and undergone resection and reconstruction operations of lower limbs in the first six months post-surgery…
- Trial name
- FISIO-ONCO (NCT06376539)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Ankle Surgery
Quality of Recovery at Days 5-7 After Ankle Surgery: a Multicenter Study in Seine-Maritime
Ankle fractures are among the most common fractures in trauma care, with an estimated annual incidence of 100 to 150 per 100,000 inhabitants and a marked increase after age 40.
- Trial name
- QoR - CHEVILLE (NCT07814937)
- Testing
- Assessment of recovery quality on days 5-7 after ankle surgery
- Where
- 4 sites in France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Rouen
Malignant Female Reproductive System Neoplasm
Enhanced Recovery After Surgery Gynecology Oncology
The aim of this study is to compare outcomes of conventional perioperative care with those of an enhanced recovery after surgery (ERAS) perioperative care plan in women undergoing open abdominal surgery for gynecologic cancer or…
- Trial name
- ERAS (NCT02864277)
- Testing
- No Intervention Conventional Strategy, ERAS
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Post-operative Residual Curarization
Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography
Diaphragm ultrasonography as a diagnostic tool in order to demonstrate the superiority of Sugammadex vs. AChEI in facilitating post-operative neuromuscular recovery.
- Trial name
- NCT02698969
- Testing
- Sugammadex, Diaphragm Ultrasonography, Neostigmine
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Florence
Total Knee Arthroplasty, Postoperative Recovery
Effects of Different Bispectral Index Target Depths on Early Postoperative Recovery Quality in Elderly Patients Undergoing Total Knee Arthroplasty
This is a prospective, single-center, randomized, double-blind controlled trial. The purpose of this study is to determine whether depth-controlled anesthesia with ciprofol guided by Bispectral Index (BIS) can improve early…
- Trial name
- NCT07906457
- Testing
- BIS-guided light-depth anesthesia management (BIS target 50-65), BIS-guided deep-depth anesthesia management (BIS target 35-50)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- General Hospital of Ningxia Medical University
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