Clinical trials: Recovery of Postoperative
Valvular Heart Disease
The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass
This study evaluates the enhanced recovery after surgery (ERAS) concept over conventional postoperative care in patients with heart valve disease undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- ERAS (NCT02479581)
- Testing
- ERAS group, Conventional control group
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Xiangya Hospital of Central South University
Laminectomy
The Effects of Ketamine and Methadone on Postoperative Pain for Laminectomy
The purpose of this research is to determine the pain-reducing effects of ketamine (Ketalar, an FDA-approved drug for anesthesia) and methadone (Dolophine, a long-acting narcotic) after lumbar laminectomy.
- Trial name
- NCT02252432
- Testing
- Ketamine, Methadone, Ketamine + methadone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Cedars-Sinai Medical Center
Hemorrhoids, Fistula
Comparison Study of the Effect of Enema in Anal Surgery
To evaluate whether receiving enema before anal surgery or not affects the postoperative recovery and complications.
- Trial name
- NCT05602987
- Testing
- enema, no enema
- Where
- Taiwan
- Volunteers
- 282 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Nursing Caries, Early Ambulation
The Effect of Early Mobilization on Postoperative Recovery in Abdominal Surgery
Objectives: This study will be conducted to determine the effect of early mobilization on postoperative recovery in abdominal surgery patients.. Methods: This research is a randomized controlled experimental study.
- Trial name
- NCT06053957
- Testing
- early mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Insomnia, Postoperative Delirium
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
The Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST) is a pilot randomized, controlled, singled-blinded (participant) trial in major orthopedic joint surgery patients that will build on a…
- Conditions
- Insomnia, Postoperative Delirium, Delayed Neurocognitive Recovery, Postoperative Neurocognitive Disorder
- Trial name
- SLEEP-BOOST (NCT06375265)
- Testing
- digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Sleep Health Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Postoperative Pain, Liposomal Bupivacaine
Efficacy of Liposomal Bupivacaine for Transversus Abdominis Plane Block
This is a single-center, randomized, single-blind, parallel-group clinical trial. The study aims to compare the analgesic efficacy of liposomal bupivacaine versus ropivacaine for transversus abdominis plane (TAP) block in…
- Trial name
- NCT07577934
- Testing
- Liposomal Bupivacaine TAP block, Ropivacaine TAP blocks
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Tianjin First Central Hospital
Enhanced Recovery After Surgery
Intraoperative Lidocaine Infusion and Surgery-induced Release of Pro-inflammatory Cytokines After Abdominal Surgery
Lidocaine is an amide local anaesthetic and an antiarrhythmic agent, first synthesized in 1942, and after approval for human use was launched in 1948 in Sweden The first observations of post operative analgesic effects of…
- Trial name
- NCT05541640
- Testing
- normal saline group, lidocaine group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cancer, Colo-rectal Cancer
Early Discharge After Colorectal Surgery
RECUPERA-C is a prospective observational pilot study evaluating the feasibility and safety of an early discharge strategy within 48 hours after minimally invasive colorectal surgery.
- Trial name
- RECUPERA-C (NCT07827378)
- Volunteers
- 97 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Spine Surgery
Lidocaine Infusion With ANI Monitoring in Spine Surgery.
To evaluate the analgesic effect of intraoperative continuous lidocaine infusion (1.5 mg/kg/h (ideal body weight)) in combination of analgesia nociception index and depth of anesthesia monitors guided anesthetics adjustment on…
- Trial name
- NCT05103215
- Testing
- Lidocaine HCl 2%, Normal saline
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Left Ventricular Dysfunction, Quality of Recovery
Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery
A randomized, controlled, double-blinded clinical trial evaluating the effect of the administration of a Maltodextrin solution on cardiac function in patients presenting for coronary artery bypass grafting surgery with a reduced…
- Conditions
- Left Ventricular Dysfunction, Quality of Recovery, Right Ventricular Dysfunction
- Trial name
- NCT05188222
- Testing
- Maltodextrin solution
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Jewish General Hospital
MRI Sedation, Pediatric Sedation
Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
The most common imaging procedure requiring sedation/anesthesia for the pediatric population is magnetic resonance imaging (MRI). However, the optimal anesthetic/sedation plan has not been determined for these procedures.
- Conditions
- MRI Sedation, Pediatric Sedation, Propofol Dosage, Emergence Delirium, Anesthesia
- Trial name
- NCT07369128
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg, Propofol (IV) 2-4 mg/kg, Dexmedetomidine (IV) 1 mcg/kg
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Boston Children's Hospital
Video-Assisted Thoracic Surgery
Quality of Postoperative Recovery (QoR-15T) in Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive technique that provides faster recovery after thoracic surgery.
- Trial name
- NCT06558331
- Testing
- Bupivacaine 0,25%, Bupivacaine 0,375%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Surgery, Laparoscopic
Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery.
- Conditions
- Surgery, Laparoscopic, Laparoscopy, Penumoperitoneum
- Trial name
- NCT06504277
- Testing
- Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator)
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
POCD - Postoperative Cognitive Dysfunction, Recovery Time
The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy
In this study, the investigators want to examine the effects of intravenous anesthetic drugs and gases on cognitive functions in the postoperative period in individuals who will undergo surgery for obesity.
- Conditions
- POCD - Postoperative Cognitive Dysfunction, Recovery Time, Postoperative Neurocognitive Disorder, Postoperative Delirium
- Trial name
- NCT07637357
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Postoperative Ileus
The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.
The effects of coffee have been shown to act as a colonic stimulant. Caffeinated coffee stimulates colonic activity, most notably in the transverse/descending colon, in magnitude similar to a meal, 60% stronger than water, and…
- Trial name
- NCT02639728
- Testing
- Regular Coffee, Decaffeinated coffee, Warm water
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Cedars-Sinai Medical Center
Patients Who Undergo Pancreaticoduodenectomy
Safety and Efficacy of Anricfen for Postoperative Analgesia and Rehabilitation Promotion After Pancreaticoduodenectomy.Intervention Measures: For Normal Adults, Administer Ariceptin Injection Intravenously Post-operation at a Dose of 1 μg/Kgevery 8 Hours for Three Consecutive Days After Surgery.
Exploring the effectiveness and safety of early use of Ariceptinfen after pancreaticoduodenectomy in alleviating postoperative pain and promoting recovery of patients.
- Trial name
- NCT07514637
- Testing
- Experimental Group, Anrikefon
- Where
- China
- Volunteers
- 35 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Dexmedetomidine, Robotic Surgery
The Effect of Dexmedetomidine on Postoperative Cognitive Function in Geriatric Patients
In pelvic surgeries, using laparoscopic surgical procedures provides advantages such as reduced postoperative pain and complications, early mobilization, shorter hospital stays, lower costs, better cosmetic outcomes, and faster…
- Conditions
- Dexmedetomidine, Robotic Surgery, Geriatric Patients
- Trial name
- NCT07047898
- Testing
- The group receiving dexmedetomidine infusion, The group not receiving dexmedetomidine infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Ileus
A Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery and Pharmacokinetics of 14C TZP-101
A study to investigate the mass balance recovery and pharmacokinetics of 14C TZP-101.
- Trial name
- NCT01668199
- Testing
- TZP-101
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Norgine
Kidney Transplantation, Anxiety
The Effects of Pre-operative Anxiety on Anesthetic Recovery and Post-operative Pain in Donor Nephrectomy
Kidney transplant is the most effective choice of treatment for patients with end-stage kidney failure in terms of quality of life and longevity. Today, 20-25% of kidney transplantations are implemented with living donors.
- Conditions
- Kidney Transplantation, Anxiety, Pain, Acute, Anesthesia Recovery Period
- Trial name
- NCT03131258
- Testing
- Donor Nephrectomy
- Volunteers
- 48 people
- Sponsor
- Ege University
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.