Clinical trials: Recovery of Postoperative
Pain, Postoperative, Postoperative Nausea and Vomiting
Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Scoliosis
- Trial name
- NCT01531439
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Children's Mercy Hospital Kansas City
Obesity &Amp; Overweight
Prehabilitation Strategies for Patients Undergoing Laparoscopic Sleeve Gastrectomy
This study aims to evaluate the effectiveness of prehabilitation strategies in patients undergoing laparoscopic sleeve gastrectomy (LSG).
- Trial name
- NCT07076901
- Testing
- Psychological Support, Supervised Exercise Program, Lifestyle and Dietary Modification
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Hebei Medical University
Analgesics, Opioid, Orthopedic Surgery
A Patient Education Video Program for Post-Operative Recovery After Upper Extremity Surgery
Adult patients undergoing elective outpatient, upper extremity, orthopedic surgeries will be randomized to view one of two educational programs: 1) a 2-video series regarding post-operative pain management or 2) a video regarding…
- Conditions
- Analgesics, Opioid, Orthopedic Surgery, Ambulatory Surgery, Education, Patient
- Trial name
- NCT03366805
- Testing
- Pain Management Patient Education Video, Wound Care Patient Education Video
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Carilion Clinic
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Cognitive Recovery, Sedation
Effects of Different Sedation Techniques on Early Cognitive Recovery After Ambulatory Gynecologic Surgery
This prospective, randomized, double-blind clinical trial aims to compare the effects of three commonly used sedoanalgesia regimens on early cognitive recovery in patients undergoing ambulatory gynecologic surgery (dilatation and…
- Conditions
- Cognitive Recovery, Sedation, Ambulatory Gynecologic Surgery, Postoperative Recovery
- Trial name
- SEDCOG (NCT07267377)
- Testing
- Propofol-Fentanyl, Ketamine-Fentanyl, Propofol + Ketamine + Fentanyl (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sait Fatih Öner
Primary Liver Cancer
Efficacy of Intravenous Lidocaine on Postoperative Pain and Recovery in Patients Undergoing Hepatectomy
Patients who meet the enrollment criteria will be randomized 1:1 to either the lidocaine or the placebo group. In the lidocaine group, at the end of the induction of general anesthesia, a bolus injection of lidocaine 1.5 mg/kg…
- Trial name
- NCT04295330
- Testing
- Lidocaine Hydrochloride, Injectable, 0.9% normal saline
- Where
- China
- Volunteers
- 260 people
- Sponsor
- West China Hospital
Quality of Recovery
Can Simple Perioperative Measures Improve Quality of Recovery Following Ambulatory Laparoscopic Surgery in Females?
The aim of this study was to assess whether it was possible to improve patients' self-assessed quality of recovery and reduce the level of post-operative nausea and vomiting in female patient undergoing laparoscopic…
- Trial name
- NCT03825666
- Testing
- ProvideXtra® Fresenius Kabi
- Volunteers
- 74 people
- Sponsor
- Danderyd Hospital
Stoma Closure, Postoperative Pain
Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Stoma Closure
After stoma closure, pain remains an important problem affecting patient recovery. A revised paravertebral block (r-PVB) was developed as a single-shot, large-volume intercostal-space injection performed at the exposed…
- Conditions
- Stoma Closure, Postoperative Pain, Quality of Recovery
- Trial name
- r-PVB III (NCT07571902)
- Testing
- Revised-Paravertebral Nerve Block
- Volunteers
- 250 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Recovery of Function
Functional Recovery Following Orthopedic Wrist Surgery Under Peripheral Nerve Block Versus General Anesthesia
This study aims at determining if there is an association between locoregional anesthesia and postoperative functional recovery for orthopedic surgery to repair a distal radial fracture, as compared to general anesthesia.
- Trial name
- FUNCTION (NCT04541745)
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Respiration Disorders
Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)
Patients operated with posterolateral thoracotomy were enrolled. Post-operative analgesia was provided either by TEA with 0.1% bupivacaine or pethidine based intravenous analgesia (IVA) in our sample population.
- Trial name
- EPAPRES (NCT03643757)
- Testing
- Thoracic epidural analgesia, Bupivacaine
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yedikule Training and Research Hospital
Total Knee Arthroplasty, Regional Anesthesia
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen following primary total knee…
- Conditions
- Total Knee Arthroplasty, Regional Anesthesia, Multimodal Analgesic Approach, Postoperative Opioid-related Complications
- Trial name
- NCT06908837
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Regionshospitalet Silkeborg
Progression, Postoperative Recovery
A Single-center Study on the Effect of Systemic/Selective Lymph Node Dissection on the Prognosis of Ground Glass Nodules Smaller Than 3cm and With Components With Consolidation/Tumor Ratio Between 0.5-1
A single-center study on the effect of systemic/selective lymph node dissection on the prognosis of ground glass nodules smaller than 3cm and with components with consolidation/tumor ratio between 0.5-1
- Trial name
- NCT05184829
- Testing
- selective lymph node dissection, Systemic Lymph Node Dissection
- Volunteers
- 500 people
- Sponsor
- Shanghai Zhongshan Hospital
Heart Transplant
Non-Intubated Anesthesia for Adult Heart Transplantation
This prospective, multicenter, randomized controlled trial aims to evaluate whether non-intubated spontaneous ventilation anesthesia (NISVA) supported by a supraglottic airway can reduce cardiopulmonary complications and promote…
- Trial name
- NISVA-HTx (NCT07758894)
- Testing
- Non-Intubated Spontaneous Ventilation Anesthesia, Conventional Anesthesia, Standardized Perioperative Anesthetic and Analgesic Medication Regimen
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Post-operative Residual Curarization
Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography
Diaphragm ultrasonography as a diagnostic tool in order to demonstrate the superiority of Sugammadex vs. AChEI in facilitating post-operative neuromuscular recovery.
- Trial name
- NCT02698969
- Testing
- Sugammadex, Diaphragm Ultrasonography, Neostigmine
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Florence
Laparoscopic Surgery of Uterus, Adnex or Ovaries, Postoperative Pain
Acupuncture Trial for Post Anaesthetic Recovery and Postoperative Pain
In the present study, the investigators want to evaluate if press needle acupuncture applied prior to surgery may contribute to the anaesthesiologic outcome.
- Trial name
- NCT01816386
- Testing
- Acupuncture Regimen, Acupressure Regimen
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Breast Cancer
Preoperative Oral Dexamethasone to Improve Recovery After Surgery
Randomized controlled trial of pre-operative oral dexamethasone vs placebo for the improvement of quality of recovery from surgery. The study population is limited to breast surgery patients.
- Trial name
- NCT02234466
- Testing
- Oral dexamethasone, Ondansetron, Gelatin capsule
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
ERAS
Assessment of Enhanced Recovery After Surgery Implementation at Pediatric Surgery Practices in Mainland China
Enhanced recovery after surgery (ERAS) is a new mode to optimize perioperative management, the core of which is to reduce perioperative physiological and psychological trauma and stress damage, and accelerate postoperative…
- Trial name
- NCT05593861
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Weibing Tang
Achilles Tendon Rupture, Blood Flow Restriction Therapy
Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair
The goal of this clinical trial is to determine whether blood flow restriction resistance training (BFR-RT) improves postoperative muscle recovery and functional outcomes following primary surgical repair of acute Achilles tendon…
- Conditions
- Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
- Trial name
- NCT07498166
- Testing
- Blood Flow Restriction Resistance Training (BFR-RT), Standard Physical Therapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Urinary Incontinence, Pelvic Organ Prolapse
Evaluation of the Benefits of Enhanced Recovery After Surgery (ERAS) Protocol in Pelvic Prolapse
ERAS protocols have been shown to improve recovery in terms of reduced pain, shortened time to ambulation and length of hospital stay.
- Trial name
- NCT04008654
- Testing
- ERAS Protocol, Conventional care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Spine Surgery
Trial of Protein Supplement on Vertebral Fusion in Posterior Spine Fusion Surgery
Receiving protein can affect the bone formation and maintenance by providing a structural matrix of the bone, optimizing the level of IGF-1, increasing intestinal calcium absorption, transferring phosphorous, and improving muscle…
- Trial name
- NCT04091841
- Testing
- protein supplement, Carbo Mass
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University
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