Clinical trials: Recovery of Postoperative
Delirium - Postoperative, Anxiety Acute
Pediatric Recovery Delirium in Pediatric Patients Undergoing Surgery
The primary aim of this observational study is to evaluate the effect of playing a mother's voice to a child while the patient is being awakened from anesthesia on postoperative delirium.
- Trial name
- Delirium (NCT07413289)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Failed Moderate Sedation During Procedure
The Effects of Single-dose Rectal Midazolam Application on Post-operative Recovery
This study aimed to compare the efficiency of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, sedation, and…
- Trial name
- NCT02127489
- Testing
- 1 mL/kg bupivacaine 0.25%.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Karadeniz Technical University
Analgesics, Opioid, Anesthetics, Local
Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery
The aim of this randomized controlled study was to investigate the effect of injecting local anesthetic agents into the sternotomy incision site and around the drains on the amount of opioids used in the postoperative period and…
- Trial name
- NCT06642077
- Testing
- LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Pain, Head and Neck Disorder
Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery
Opioid tolerance in the perioperative period is inevitable especially with ultra-short acting agents such as remifentanil. Existing evidence had shown that opioid induced hyperalgesia due to neuroplastic changes in the central as…
- Trial name
- NCT02416752
- Testing
- Remifentanil, choice of intra-operative opioids were left to the discretion of anesthesiologist
- Where
- Singapore
- Volunteers
- 222 people
- Sponsor
- Singapore General Hospital
Ambulation Difficulty, Colorectal Surgery
Tolerance of Early Postoperative Mobilization and Ambulation
Enhanced recovery programme (ERP) includes early postoperative mobilization and ambulation the day of surgery. Data suggest that orthostatic symptoms prevent a large number of patients from ambulating the day of surgery.
- Conditions
- Ambulation Difficulty, Colorectal Surgery, Bariatric Surgery
- Trial name
- MOBTOL (NCT04040647)
- Testing
- mobilization and ambulation
- Where
- 2 sites in Belgium
- Volunteers
- 88 people
- Sponsor
- University of Liege
Postoperative Recovery in Elderly Patients, Quality of Recovery After Elective Surgery
Postoperative Recovery in Elderly Patients Assessed With QoR-15E
Postoperative recovery in elderly patients is an important part of the surgical process and affects how patients feel after surgery.
- Conditions
- Postoperative Recovery in Elderly Patients, Quality of Recovery After Elective Surgery, Perioperative Care Outcomes in Older Adults
- Trial name
- PQoRE (NCT07505758)
- Testing
- QoR-15E questionnaire., Clinical Frailty Scale, Confusional Assessment Method
- Where
- 4 sites in Spain
- Volunteers
- 600 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Laparoscopic Sleeve Gastrectomy (LSG)
Combining Dexmedetomidine Infusion and Paragastric Autonomic Neural Block to Enhance Postoperative Recovery in Patients Undergoing Laparoscopic Sleeve Gastrectomy
The goal of this clinical trial is to learn if combining Dexmedetomidine infusion and paragastric autonomic neural block will enhance the postoperative recovery of patients undergoing laparoscopic sleeve gastrectomy.
- Trial name
- NCT06970678
- Testing
- Dexmedetomidine infusion, paragastric autonomic neural block
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Alexandria University
Abdominal Surgeries
Enhanced Recovery After Surgery (ERAS) Protocols on Postoperative Outcomes in Patients Undergoing Major Abdominal Procedures
ERAS protocols are still only partially and unevenly implemented in many hospitals in developing nations, despite substantial worldwide evidence to the contrary.
- Trial name
- NCT07855328
- Testing
- ERAS, Standard Care (in control arm)
- Volunteers
- 166 people
- Sponsor
- Dr Mudassar Saeed Pansota
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo
Obstructive Sleep Apnea
Impact of Sugammadex vs. Neostigmine Reversal on Post-Operative Recovery and Complications
Sugammadex or neostigmine are given at the end of the surgery to reverse neuro muscular blocking drugs (NMBD). This study will evaluate whether reversal of NMBD with sugammadex is associated with faster recovery than neostigmine…
- Trial name
- Sugammadex (NCT03679611)
- Testing
- Sugammadex Sodium, Neostigmine
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Cognitive Recovery, Sedation
Effects of Different Sedation Techniques on Early Cognitive Recovery After Ambulatory Gynecologic Surgery
This prospective, randomized, double-blind clinical trial aims to compare the effects of three commonly used sedoanalgesia regimens on early cognitive recovery in patients undergoing ambulatory gynecologic surgery (dilatation and…
- Conditions
- Cognitive Recovery, Sedation, Ambulatory Gynecologic Surgery, Postoperative Recovery
- Trial name
- SEDCOG (NCT07267377)
- Testing
- Propofol-Fentanyl, Ketamine-Fentanyl, Propofol + Ketamine + Fentanyl (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sait Fatih Öner
Total Knee Arthroplasty, Postoperative Recovery
Effects of Different Bispectral Index Target Depths on Early Postoperative Recovery Quality in Elderly Patients Undergoing Total Knee Arthroplasty
This is a prospective, single-center, randomized, double-blind controlled trial. The purpose of this study is to determine whether depth-controlled anesthesia with ciprofol guided by Bispectral Index (BIS) can improve early…
- Trial name
- NCT07906457
- Testing
- BIS-guided light-depth anesthesia management (BIS target 50-65), BIS-guided deep-depth anesthesia management (BIS target 35-50)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- General Hospital of Ningxia Medical University
Knee Arthroscopy
Assessing the Effects of Sublingual Sufentanil 30 µg on Postoperative Recovery
A pilot study to evaluate the effect of incorporating sublingual sufentanil into our perioperative opioid regimen for ambulatory orthopedic surgery.
- Trial name
- NCT04561375
- Testing
- Sufentanil, Fentanyl
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- The Cleveland Clinic
Unilateral Hip Fracture
Improving Functional Recovery After Hip Fracture
This project will assess the effectiveness of a novel approach involving patient education and strength training to improve functional recovery after a hip fracture.
- Trial name
- NCT00000436
- Testing
- Self-efficacy and muscle strength training, High-intensity strength training
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty
Perioperative Colchicine for TKA
This study is a prospective, randomized, double-blinded, placebo-controlled study of the drug colchicine in the acute postoperative period for patients who are undergoing a total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty, Perioperative Pain Control
- Trial name
- NCT06936709
- Testing
- Colchicine 1.8 mg + 0.6 mg
- Volunteers
- 75 people
- Sponsor
- Geisinger Clinic
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04858711
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Recovery From Bariatric Surgery
The Effect of Premedication With Melatonin on Postoperative Recovery From Bariatric Surgery
Melatonin has sedative, hypnotic and analgesic properties that make it a good premedication agent before anesthesia and surgery.
- Trial name
- NCT02424071
- Testing
- Melatonin
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cancer of Colon
Implementation of Enhanced Recovery After Surgery Program (ERAS) in Colorectal Cancer Surgery, a Randomized Controlled Trial
The aim of our study is to determine the effect of implementation of the ERAS (enhanced recovery after surgery) protocol in our institute and its impact on hospital length of stay and outcome of surgery.
- Trial name
- NCT03928678
- Testing
- enhanced recovery after surgery program in colorectal cancer surgery
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pain, Surgery
(TAP) Block vs. Systemic Lidocaine: Effects on Recovery
It has been demonstrated that female patients have poor quality of surgical recovery compared to male patients. Increased sensitivity to pain and increased susceptibility to postoperative nausea and vomiting have been attributed…
- Trial name
- TAP (NCT02053558)
- Testing
- Systemic lidocaine, TAP BLOCK with ropivacaine
- Sponsor
- Northwestern University
Cardiovascular Disease
The Effect of Osteopathic Manipulative Treatment on Recovery of Coronary Bypass Patients
The purpose of the study was to determine the effect on recovery after surgery of patients who received a standardized daily protocol of osteopathic manipulative treatment.Patients undergoing elective coronary artery bypass…
- Trial name
- CABGOMT (NCT00504179)
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Michigan State University
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