Clinical trials: Recruitment
Postoperative Pulmonary Atelectasis, Negative Pressure Therapy
Evaluation of the Effect of Novel Recruitment Maneuver Therapy for Postoperative Pulmonary Atelectasis
1. Oxygenation index and bedside ultrasound would be used to evaluate the therapeutic effect of novel recruitment maneuver therapy in the patients with pulmonary atelectasis after cardiac surgery. 2.
- Trial name
- NCT06049173
- Testing
- Negative extra-abdominal pressure (NEXAP)-based lung recruitment maneuver, stepwise positive end-expiratory pressure (PEEP)-based lung recruitment maneuver
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Jilai Xiao
Healthy
Healthy Volunteer Recruitment and Characterization for NINDS Studies
Background: The National Institute of Neurological Disorders and Stroke (NINDS) often enrolls healthy volunteers in certain studies.
- Trial name
- NCT07700511
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Obesity
Non Invasive Pressure Support Ventilation (NIPPV) Versus Recruitment Maneuver (RM) and Preoxygenation
The purpose of this study is to compare the effects of noninvasive pressure support ventilation and early alveolar recruitment maneuver during anesthesia induction of morbidly obese patients on both oxygenation and functional…
- Trial name
- NCT00852384
- Testing
- NIPPV and IRM
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Demographic Data, History of Medical and Mental Health
VISN 19 MIRECC Research Database
The VISN 19 MIRECC is involved in research concerned with suicide prevention in high risk populations (e.g., history of traumatic brain injury, post-traumatic stress disorder); Recruitment for future studies will continue with a…
- Conditions
- Demographic Data, History of Medical and Mental Health, History of Combat Experience, History of Suicide
- Trial name
- Repository (NCT01334476)
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- VA Eastern Colorado Health Care System
Perioperative Complication, Hypoxia
Prevention of Perioperative Pulmonary Complications by Lung Recruitment During Laparoscopic Surgery
Perioperative pulmonary complications such as atelectasis, hypoxemia, and pneumonia after ventilatory management during general anesthesia have a negative impact on patient outcomes.
- Trial name
- NCT04728945
- Testing
- lung recruitment, Standard ventilatory management
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Osaka University
Abdominal Cancer
Individualized Lung Recruitment Maneuver Guide by Pulse-oximetry in Anesthetized Patients
General anesthesia and mechanical ventilation promotes atelectasis and airway closure. The open-lung approach (OLA) strategy restores the functional residual capacity.
- Trial name
- NCT02912819
- Testing
- Open-lung approach
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Mechanical Ventilation
Sigh in Pressure Support Ventilation to Detect Respiratory System Compliance and Lung Recruitability
The goal of this physiological study is to determine whether ventilator-delivered sigh breaths during pressure support ventilation (PSV) provide a reliable bedside index of lung recruitability and can guide PEEP optimization.The…
- Trial name
- NCT07172061
- Testing
- PSV + sigh (Clinical PEEP and Clinical PEEP + 3 cmH₂O)
- Where
- 2 sites in Italy
- Volunteers
- 110 people
- Sponsor
- AUSL Romagna Rimini
Respiratory Distress Syndrome, Newborn
Role of Lung Ultrasound In Assessment Of Recruitment Maneuvers In Ventilated Preterms With Respiratory Distress Syndrome and Its Correlation With Tracheal IL-6 Level
This work is designed to: 1. Evaluate the efficacy of lung ultrasonography in detecting opening and closing lung pressures in ventilated preterm neonates with respiratory distress syndrome. 2.
- Trial name
- NCT04107090
- Testing
- lung recruitment maneuver, tracheal IL-6 level, US guided lung recruitment maneuver
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Ain Shams University
Lung Cancer, Patient Engagement
Improving Access to Lung Cancer Clinical Trials
There are ~85,000 lung cancer patients (LCPs) in the UK; yet only around 8% were recruited into clinical trials in 2021/22. LCPs need opportunities to take part in clinical trials to access new treatments, increasing their…
- Conditions
- Lung Cancer, Patient Engagement, Research, Communication, Nurse-Patient Relations
- Trial name
- Lung I-ACT (NCT05780164)
- Testing
- Research readiness tool
- Where
- United Kingdom
- Volunteers
- 109 people
- Sponsor
- Oxford Brookes University
Prediabetes
Continuous Glucose Monitoring (CGM) in Prediabetes With Community Based Recruitment
The objective of this project is to develop a behavioral intervention that combines wearable continuous glucose monitoring (CGM) with smartphone feedback and educational video clips generated by artificial intelligence (AI)…
- Trial name
- G3 (NCT07477249)
- Testing
- CGM
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- David S Black, PhD
Hypoxemia
Recruitment Maneuver After Intubation
The purpose of this study is to evaluate the safety and efficacy of a recruitment maneuver immediately after intubation in hypoxemic patients.
- Trial name
- NCT01014299
- Testing
- Recruitment maneuver
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
ARDS, Human, Ventilation Therapy; Complications
Assessment of the Hemodynamic Effects of PEEP According to Alveolar Recruitment During the ARDS
The corner stone of the treatment of ARDS is mechanical ventilation with high levels of positive end-expiratory pressure, also called PEEP. A high level of PEEP is recommended and frequently used.
- Conditions
- ARDS, Human, Ventilation Therapy; Complications, Alveolar; Disorder
- Trial name
- NCT05524558
- Testing
- Pulmonary artery catheter, Esophagal pressure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Bicetre Hospital
Idiopathic Scoliosis
Anesthesia and Motor Evoked Potential (MEP) Recruitment
Test the hypothesis to recruit larger motor responses to transcranial stimulation.
- Trial name
- NCT02199314
- Testing
- Desflurane
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Septic Shock
Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients
The aim of this study is to evaluate the effect of combining HSA 20% and terlipressin on the microcirculation in patients with septic shock using the following;- Microcirculation recruitment by Cytocam-IDF.
- Trial name
- NCT05080543
- Testing
- Albumin 20% and terlipressin
- Volunteers
- 36 people
- Sponsor
- Amany Mousa Salama Muhammed
COPD Exacerbation
Once Daily Long-Acting Muscarinic Antagonists Administered in the Evening for Prevention of Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization or Death from Any Cause
To examine, among once-daily LAMA using COPD patients, whether evening administration of LAMA is superior with respect to the incidence of hospitalization requiring AECOPD or death from all causes than the more conventional…
- Trial name
- NCT05563675
- Testing
- Long acting muscarinic antagonists (LAMAs) in the evening
- Where
- Denmark
- Volunteers
- 10,011 people
- Sponsor
- Chronic Obstructive Pulmonary Disease Trial Network, Denmark
Atelectasis
Role of Lung Ultrasound Imaging in the Comparison of Two Mechanical Ventilation Strategies During Laparotomy
The use of positive end-expiratory pressure (PEEP) and recruitment maneuvers during laparotomy will limit the development of atelectasis and therefore improve the aeration score.
- Trial name
- NCT02055807
- Testing
- PEEP and recruitment maneuvers, ZEEP (no PEEP nor recruitment maneuver)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Thoracic, Diseases
The Effect of Two Airway Interventions, During One Lung Ventilation, on Blood Oxygen Content
Patients requiring one lung ventilation (OLV) for open thoracic surgery will be ventilated (breathing performed by a breathing machine) during anesthesia using a lung protective ventilation strategy (small breath volumes at…
- Trial name
- NCT01495936
- Testing
- RM + Positive End Expiratory Pressure, Continuous Positive Airway Pressure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Body Dysmorphic Disorders
Feasibility Pilot Study of Internet-based Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder With Global Recruitment
The aim of the study is to study an english-language version of BDD-NET (Enander, et al., 2014; Enander, et al., 2016), an internet-based treatment for Body Dysmorphic Disorder, on a globally recruited sample.
- Trial name
- BDD-G (NCT03517384)
- Testing
- I-CBT for Body Dysmorphic Disorder
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Respiratory Distress Syndrome, Newborn, Bronchopulmonary Dysplasia
High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation and Stability of Oxygenation
Background: Ventilator induced lung injury (VILI) remains a problem in neonatology. High frequency oscillatory ventilation (HFOV) provides effective gas exchange with minimal pressure fluctuation around a continuous distending…
- Conditions
- Respiratory Distress Syndrome, Newborn, Bronchopulmonary Dysplasia, Ventilator Induced Lung Injury
- Trial name
- NCT01959009
- Testing
- HFOV combined with sigh breaths
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Electrical Impedance Tomography (EIT), Postoperative Pulmonary Complications (PPCs)
EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery
This study is a prospective, single-center, single-blind, randomized controlled clinical trial. Patients scheduled for laparoscopic bariatric surgery will be selected and randomly assigned to either the EIT-guided individualized…
- Conditions
- Electrical Impedance Tomography (EIT), Postoperative Pulmonary Complications (PPCs), Recruitment, Mechanical Ventilation Complication
- Trial name
- EIT (NCT07207772)
- Testing
- Group P-eit, Group P-8
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Jianbo Wu