Clinical trials: Recruitment, open to volunteers
Early Pregnancy
Conversational AI Platform for Early Pregnancy Care City-wide Recruitment: A Feasibility Study
This study seeks to determine pregnant patients in the Philadelphia area can be recruited to a conversational AI texting platform.
- Trial name
- CIRCA (NCT07197892)
- Testing
- CIRCA Texting Platform
- Where
- United States
- Volunteers
- 2,637 people
- Sponsor
- University of Pennsylvania
Thoracic Aortic Disease
Accessing the Clarity and Acceptability of Recruitment Materials for a Study on Thoracic Aortic Disease Surveillance
People who are invited to take part in health research are usually given written information, such as invitation letters, and information sheets.
- Trial name
- ACCESS-TAD (NCT07574151)
- Testing
- Acceptability and Clarity
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Atelectasis, Mechanical Ventilation
Effects of Periodic Recruitment Maneuvers on Atelectasis and Respiratory Mechanics During Elective Spine Surgery Assessed by Lung Ultrasonography
During general anesthesia, particularly in patients undergoing spine surgery in the prone (face-down) position, increased intrathoracic and abdominal pressure may reduce lung compliance and promote the development of atelectasis…
- Conditions
- Atelectasis, Mechanical Ventilation, General Anesthesia, Prone Position
- Trial name
- NCT07325812
- Testing
- Alveolar Recruitment Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Major Abdominal Surgery, Atelectasis
Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Ventilation
This study aims to determine the optimal interval for periodic alveolar recruitment maneuvers (PARM) that can achieve effective lung re-expansion in 90% of patients undergoing intraoperative mechanical ventilation during…
- Conditions
- Major Abdominal Surgery, Atelectasis, Lung-protective Ventilation, Lung Ultrasound Score
- Trial name
- NCT07239557
- Testing
- Different interval of PARM
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pain, Post-operative, Pneumoperitoneum
Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain
The goal of this clinical trial is to evaluate whether different positioning in the operating room during removal of laparoscopic surgical gas differs in post-surgery shoulder pain.
- Conditions
- Pain, Post-operative, Pneumoperitoneum, Urogynecologic Surgery
- Trial name
- NCT07631728
- Testing
- Pulmonary recruitment maneuver, Trendelenburg position
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankita Gupta
Consent Process
Examining the Efficacy of a Digital Media Intervention to Increase Recruitment Rates
WHEAT-Boost is a Study Within A Trial (SWAT) that aims to improve how families are recruited into neonatal research studies by testing a new way of sharing information.
- Trial name
- WHEAT-Boost (NCT07284329)
- Testing
- Intervention (Video) Arm
- Where
- 15 sites in Canada
- Volunteers
- 787 people
- Sponsor
- IWK Health Centre
Obesity
Supporting Decisions on Lifestyle Change
This study will test the effects of a brief, individually tailored intervention aiming to increase initiation of comprehensive behavioral weight loss treatment on weight.
- Trial name
- NCT06206954
- Testing
- MyHealthPath Tool, MyHealthPath Guide
- Where
- United States
- Volunteers
- 864 people
- Sponsor
- University of Florida
Spinal Cord Injuries and Disorders (SCI/D), Spinal Cord Injury
Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)
The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections.
- Trial name
- NCT07179822
- Testing
- Motor Evoked Potential (MEP) Operant Conditioning
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Laparoscopic Surgery, Positive End-Expiratory Pressure
Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients
Abdominal laparoscopy is widely utilized due to its benefits, including minimal invasiveness, improved cosmetic outcomes, and shorter hospital stays.
- Conditions
- Laparoscopic Surgery, Positive End-Expiratory Pressure, Electrical Impedance Tomography
- Trial name
- PEEP-EIT (NCT06850844)
- Testing
- electrical impedance tomography, Conventional Ventilation
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Acute Respiratory Distress Syndrome (ARDS)
COMPARISON OF LUNG RECRUITABILITY ASSESSMENT BY HYSTERESIS RATIO AND RECRUITMENT-TO-INFLATION RATIO, AND PEEP TITRATION IN ARDS.
This multicenter, single-blind physiological study aims to compare two bedside methods for assessing lung recruitability in mechanically ventilated patients with acute respiratory distress syndrome (ARDS): the…
- Trial name
- PV-TOOL (NCT07713420)
- Testing
- Physiological lung recruitability assessment and PEEP titration protocol
- Volunteers
- 30 people
- Sponsor
- Oriol Roca
Intracranial Pressure Increase, Mechanical Ventilation Complication
Lung Recruitment and PEEP Effects on Intracranial Pressure in Cranial Surgery
High positive end-expiratory pressure (PEEP) levels required to achieve clinical benefits may increase ICP and reduce cerebral perfusion pressure (CPP) in patients at risk of intracranial hypertension.
- Trial name
- NCT06771232
- Testing
- Subdural pressure measurement
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS)
Observational Study on the Causal Architecture of Polycystic Ovary Syndrome (PCOS)
The goal of this observational study is to learn about the causal architecture of Polycystic Ovary Syndrome (PCOS) in women aged 18 to 45.
- Conditions
- Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS), PCOS, PCOS (Polycystic Ovary Syndrome)
- Trial name
- NCT07623551
- Testing
- No intervention - observational data collection only
- Volunteers
- 100 people
- Sponsor
- AnnieGuard Corp.
Recruitment, Respiratory Failure
Positive Expiratory Pressure (PEP) and Continuous High-frequency Oscillation (CHFO) on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study
This single-center observational study aims to assess the effects of continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy on lung recruitment using electrical impedance…
- Trial name
- PEP-RECRUIT (NCT06689020)
- Testing
- Continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Genova
Diaphragm
Recruitment of the Diaphragm and Sternocleidomastoid Muscle During Loaded Inspiration on Varying Sitting Support in Healthy Adults
This is a cross-sectional obsessional study. This study explores how different sitting conditions affect two important muscles-the diaphragm and the sternocleidomastoid (SCM)-work during breathing exercises.
- Trial name
- NCT07007923
- Where
- Hong Kong
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Postoperative Atelectasis, Lung Ultrasonography Score
Evaluation of Recruitment Effectiveness in Patients With Obstructive Sleep Apnea Syndrome Using Lung Ultrasound
Patients with obstructive sleep apnea syndrome are at higher risk for respiratory complications after surgery. Oxygen depletion and respiratory distress are common in patients with obstructive sleep apnea syndrome.
- Conditions
- Postoperative Atelectasis, Lung Ultrasonography Score, Recruitment
- Trial name
- NCT07061002
- Testing
- Lung Recruitment Maneuver, Positional Lung Recruitment Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
Acute Respiratory Distress Syndrome (ARDS)
Assessment of the Reproducibility of the Recruitment-to-inflation Ratio (R/I Ratio) Measurement in Patients With Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is a severe lung condition that often requires invasive mechanical ventilation in the intensive care unit.
- Trial name
- RIRR (NCT07666503)
- Where
- 4 sites in France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pseudoxanthoma Elasticum
Impact of Optimized Recruitment and Follow-up of Patients With Pseudoxanthoma Elasticum (PXE)
Pseudoxanthoma elasticum (PXE) is a rare genetic disorder characterized by ectopic calcifications in the skin, retina and arterial walls. Angers University Hospital is the national rare disease reference center (CRMR) for PXE.
- Trial name
- REMOTE-PXE (NCT06636344)
- Testing
- Pseudoxanthoma Elasticum
- Where
- France
- Volunteers
- 650 people
- Sponsor
- University Hospital, Angers
Pulmonary Artery Hypertension
Sotatercept in Pulmonary Arterial Hypertension
The goal of this clinical trial is to determine whether sotatercept is effective in improving diffusing capacity in patients with pulmonary arterial hypertension.
- Trial name
- NCT07140484
- Testing
- Sotatercept
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Psoriasis, Social Isolation
Walk and Talk: Connecting People With Psoriasis
The main aim of this study is to determine the acceptability, representativeness (e.g. age, sex, ethnicity and body mass index) and ideal format of a Walk and Talk intervention for people with psoriasis.
- Trial name
- NCT06726213
- Testing
- Walk and talk
- Where
- United Kingdom
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Mechanical Ventilation
Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients
Patients who are intubated and mechanically ventilated in the intensive care unit (ICU) require repeated endotracheal suctioning to remove airway secretions.
- Trial name
- RESPIRE (NCT07358039)
- Testing
- Suction + Recruitment maneuver, Closed-circuit endotracheal suctioning
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer