Clinical trials: Rectal Cancer, completed
Colorectal Cancer
Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery
This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery.
- Trial name
- NCT07144475
- Testing
- Lactobacillus casei Shirota, Lactobacillus acidophilus
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Dharmais National Cancer Center Hospital
Anal Cancer
Radiation Dosimetry Study Comparing 2 Different Patient Setups in Anal/Rectal Cancer Patients
The study compares two patient setups (Standard Prone vs. Genital Drop Technique) with identical radiation treatment technique and parameters.
- Trial name
- NCT00693173
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Colorectal Cancer
An Observational Study of Avastin and Conventional Chemotherapy in Patients >/= 70 Years of Age With Previously Untreated Metastatic Colorectal Cancer (AVAPLUS)
This observational study will evaluate the use of Avastin (bevacizumab) and conventional chemotherapy in patients >/= 70 years of age with previously untreated metastatic colorectal cancer.
- Trial name
- NCT01676922
- Where
- 33 sites in Belgium
- Volunteers
- 256 people
- Sponsor
- Hoffmann-La Roche
Stage I Colorectal Cancer AJCC v8, Stage II Colorectal Cancer AJCC v8
Diet Education Program for Stage I-IV Colorectal Cancer Survivors
This pilot trial evaluates the feasibility of a group diet education program for stage I-IV colorectal cancer survivors. Providing a nutrition education program for colon and rectal cancer survivors may help them have better…
- Conditions
- Stage I Colorectal Cancer AJCC v8, Stage II Colorectal Cancer AJCC v8, Stage IIA Colorectal Cancer AJCC v8, Stage IIB Colorectal Cancer AJCC v8
- Trial name
- NCT04597151
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of California, San Francisco
Colorectal Cancer, Esophageal Cancer
Nutritional Status and Nutrient Supply in Hospitalised Surgical Patients
Prospective single arm, single center observational study to assess the nutritional status and the nutrient supply during hospitalization for elective gastrointestinal surgery.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT03787537
- Where
- Germany
- Volunteers
- 128 people
- Sponsor
- Charite University, Berlin, Germany
Cancer, Breast, Cancer, Colon
Enhancing Cancer Prevention and Control Pathways-Native Health Initiative
There are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US.
- Conditions
- Cancer, Breast, Cancer, Colon, Cancer, Cervix
- Trial name
- NCT04259762
- Testing
- Aim 8 (INT, Pilot Test): Breast, Colorectal, and Cervical Cancer Screening Cognitive-Behavioral Interventions
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance
Colorectal Cancer, Microsatellite Instability
National Cohort of Colorectal Cancers With Microsatellite Instability
The three main pathways of colorectal carcinogenesis are chromosomal instability, microsatellite instability (MSI) (15% of colorectal cancers =CRCs) and CpG island methylator phenotype (CIMP).
- Trial name
- NCT05511688
- Where
- 14 sites in France
- Volunteers
- 637 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Metastatic Colorectal Cancer
Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer
One of the treatments generally used to treat this disease is a chemotherapy called FOLFIRI. The purpose of this study is to improve the efficacy of the chemotherapy by adding a protein, similar to immunoglobulins, aflibercept…
- Trial name
- NCT02181556
- Testing
- FOLFIRI Protocol, Aflibercept Injection
- Where
- 8 sites in France
- Volunteers
- 41 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Cancer
Interleukin-12 in Treating Patients With Refractory Advanced-Stage Ovarian Cancer or Abdominal Cancer
Phase I trial to study the effectiveness of interleukin-12 in treating patients with refractory ovarian or abdominal cancers. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a persons's…
- Trial name
- NCT00003439
- Testing
- recombinant interleukin-12
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
Tumor, Solid, Gall Bladder Cancer
Study With Andes-1537 in Patients With Specific Types of Advanced Solid Tumor
The study is a Phase 1 Open-label Two-stage, Safety and Tolerability Study with Cancer Type-specific Cohorts, Evaluating Subcutaneous Administration of Andes-1537 for Injection in Patients with Advanced Solid Tumors that are…
- Conditions
- Tumor, Solid, Gall Bladder Cancer, Cervical Cancer, Gastric Cancer
- Trial name
- NCT03985072
- Testing
- Andes-1537 for Injection
- Where
- 4 sites in Chile
- Volunteers
- 67 people
- Sponsor
- Andes Biotechnologies
ColoRectal Cancer
Impact of HLA-E Overexpression by Tumor Cells on the Biology of TIL in Colorectal Cancer
Accumulating evidences suggest that colorectal cancer (CRC) progression is not solely determined by the genetic abnormalities of the tumor cells but also by the host response.
- Trial name
- HLA-E CCR (NCT02980146)
- Testing
- Non interventional study
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Nantes University Hospital
Rectal Cancer, Radiotherapy
IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.
The goal of this prospective phase II study was to determine whether personalized planning-based nCRT for LARC would indeed decrease small bowel dose, and whether selected plans, specifically prioritizing lower dose to small…
- Conditions
- Rectal Cancer, Radiotherapy, Toxicity Due to Radiotherapy
- Trial name
- NCT06160570
- Testing
- Intensive Modulated Radiation Therapy, 3-Dimension Conformal Radiation Therapy
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Rabin Medical Center
Colorectal Cancer, Advanced Adenocarcinoma
Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study
This study was a prospective analysis conducted by Geneoscopy Inc. to evaluate the ColoSense test, which is a multi-target stool RNA test for colorectal cancer screening.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Serrated Polyp
- Trial name
- CRC-PREVENT (NCT04739722)
- Testing
- ColoSense
- Where
- 2 sites in United States
- Volunteers
- 14,263 people, healthy volunteers welcome
- Sponsor
- Geneoscopy, Inc.
Colorectal Cancer, Colorectal Tumors
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread
The purpose of this study is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer of the colon or rectum that has spread.
- Conditions
- Colorectal Cancer, Colorectal Tumors, Colorectal Carcinoma, Colorectal Neoplasm
- Trial name
- CheckMate 9N9 (NCT03377361)
- Testing
- Nivolumab, Trametinib, Ipilimumab
- Where
- 47 sites in United States, Argentina and 8 more
- Volunteers
- 325 people
- Sponsor
- Bristol-Myers Squibb
Metastatic Colorectal Cancer
Study of Glutamine as Prophylaxis for Irinotecan Induced Diarrhea
Irinotecan (7-ethyl-10- {4(-1-piperidino)-1-piperidino} carbonyloxy camptothecin) is a semisynthetic camptothecin derivative introduced in the 1980's.
- Trial name
- NCT00255229
- Testing
- Glutamine
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- AHS Cancer Control Alberta
Rectal Cancer
Phase I Trial of Ganetespib, Capecitabine, and Radiation in Rectal Cancer
The purpose of this study is to find out what effects, good and/or bad, the combination of the study drug, capecitabine, and radiation have on you and your cancer.
- Trial name
- NCT01554969
- Testing
- capecitabine + ganetespib
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Emory University
Colorectal Cancer
A Phase II Trial Assessing Nivolumab in Class II Expressing Microsatellite Stable Colorectal Cancer
An open-label, single-arm, phase II, multicentre clinical trial to determine the rate of durable clinical benefit of nivolumab in patients with class II expressing microsatellite stable colorectal cancer.
- Trial name
- ANICCA (NCT03981146)
- Testing
- Nivolumab
- Where
- 14 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Birmingham
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer
Randomized phase III trial to compare the effectiveness of fluorouracil given by infusion with that of fluorouracil plus eniluracil given by mouth in treating patients who have metastatic, recurrent, or residual advanced…
- Conditions
- Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Recurrent Colon Cancer, Recurrent Rectal Cancer
- Trial name
- NCT00003873
- Testing
- fluorouracil, eniluracil
- Where
- United States
- Volunteers
- 950 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Cetuximab & Celecoxib for Metastatic Colorectal Cancer or Colorectal Cancer That Cannot Be Removed by Surgery
RATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00466505
- Testing
- cetuximab, celecoxib, proteomic profiling
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Colorectal Cancer
A Phase 2 Study of Tomudex & Iressa as Second Line Chemotherapy in Subjects With Colorectal Carcinoma
The primary objective of this study is to compare the activity of raltitrexed and ZD1839 versus raltitrexed alone as second line chemotherapy in subjects with colorectal carcinoma by estimating progression free survival (PFS) in…
- Trial name
- NCT00234429
- Testing
- Gefitinib, raltitrexed
- Where
- 9 sites in Spain
- Volunteers
- 74 people
- Sponsor
- AstraZeneca
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