Clinical trials: Rectal Cancer, completed
Metastatic Colorectal Cancer
P13Kinase Inhibitor BKM120 in Combination With Panitumumab in Metastatic/Advanced RAS-Wild Type Colorectal Cancer.
For the first phase of this study (phase I), the purpose will be to find the dose of a new drug, BKM120, that can safely be given in combination with standard dose panitumumab.
- Trial name
- NCT01591421
- Testing
- BKM120, Panitumumab
- Where
- 3 sites in Canada
- Volunteers
- 22 people
- Sponsor
- Canadian Cancer Trials Group
Anal Cancer
Anal Cancer Screening Study
Background: HIV-positive men who have sex with men (MSM) have rates of anal cancer that approach those of cervical cancer in women.
- Trial name
- NCT00914537
- Where
- United States
- Volunteers
- 363 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Accelerated Enhanced RECOVERy Following Minimally Invasive Colorectal Cancer Surgery (RecoverMI)
The goal of this clinical research study is to learn if RecoverMI care can help to shorten the time that patients are in the hospital after surgery and if it can help them recover sooner.
- Trial name
- NCT02613728
- Testing
- Accelerated Recovery Plan, Early Discharge, Telemedicine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- M.D. Anderson Cancer Center
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Colo-rectal Cancer
Single-stapled Double Purse-string Technique for Colorectal Anastomosis
A single-arm, single-center prospective study of a novel double purse-string technique for constructing the colorectal anastomosis in robot-assisted laparoscopic resection of the sigmoid colon for cancer.
- Trial name
- NCT04223141
- Testing
- SIA
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Vejle Hospital
Colorectal Cancer
Combination Chemotherapy With or Without Celecoxib in Treating Patients With Metastatic Colorectal Cancer
RATIONALE: Drugs used in chemotherapy such as irinotecan, capecitabine, leucovorin, and fluorouracil use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00064181
- Testing
- FOLFIRI regimen, capecitabine, celecoxib
- Where
- 28 sites in Belgium, Egypt and 3 more
- Volunteers
- 86 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Colorectal Cancer
Studying DNA and Outcome in Patients With Advanced Colorectal Cancer Treated With Fluorouracil and Oxaliplatin With or Without Bevacizumab on Clinial Trial E-3200
RATIONALE: Studying samples of blood, urine, and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00897819
- Testing
- DNA methylation analysis, loss of heterozygosity analysis, microsatellite instability analysis
- Volunteers
- 350 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Anastomotic Leak, Colorectal Cancer
Predictors of Rescue Surgery, Mortality, and Permanent Stoma After Anastomotic Leak Following Colorectal Cancer Resection
Anastomotic leakage is a serious complication following colorectal cancer resection and may result in emergency reoperation, severe sepsis, death, loss of the colorectal anastomosis, and formation of a long-term or permanent…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Colon Cancer, Postoperative Complication
- Trial name
- leak predictor (NCT07725692)
- Where
- Egypt
- Volunteers
- 3,200 people
- Sponsor
- Alexandria University
Decision Aid
Using Visual Arrays to Support Understanding of Genetic Risk
The goal of this study is to understand how people understand risk from genetic testing. The investigators want to understand what visual aid best helps people accurately assess risk.
- Trial name
- NCT06994832
- Testing
- Visual Array, Narrative Visual Array, Choice
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- Stephanie B. Seminara, MD
Breast Neoplasms, Colorectal Neoplasms
Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors
This is a Phase 1 open-label study of SN2310 Injectable Emulsion in patients with advanced solid malignancies. The study is designed to determine the maximum tolerated dose and dose-limiting toxicity of SN2310 Injectable…
- Conditions
- Breast Neoplasms, Colorectal Neoplasms, Pancreatic Neoplasms, Pelvic Neoplasms
- Trial name
- NCT00385177
- Testing
- SN2310 Injectable Emulsion
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Achieve Life Sciences
Colorectal Cancer, Rectal Cancer
A Prediction Model of Anastomotic Stricture After Rectal Cancer
Background: Anastomotic stricture significantly impacts patients' quality of life and long-term prognosis. However, current clinical practice lacks accurate tools for predicting anastomotic stricture.
- Conditions
- Colorectal Cancer, Rectal Cancer, Anastomotic Stenosis
- Trial name
- NCT06404554
- Testing
- without any intervention
- Where
- China
- Volunteers
- 1,542 people
- Sponsor
- Northern Jiangsu People's Hospital
Colorectal Cancer
Probiotic Supplementation During Neoadjuvant Chemoradiotherapy in Colorectal Cancer
This prospective randomized, double-blind, placebo-controlled study evaluated the effects of multistrain probiotic supplementation in patients with stage II-III colorectal cancer undergoing neoadjuvant chemoradiotherapy.
- Trial name
- NCT07863154
- Testing
- Multistrain Probiotic Formulation
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- University of Malaga
Rectal Neoplasms, Neuroendocrine Tumors
Clinical Relevance of the Salvage Treatment for Colorectal Neuroendocrine Tumors
we evaluated all related clinical and pathologic data of rectal NET cases, including the resection margin status, NET grading, and lymphovascular invasion status.
- Trial name
- NCT06143605
- Testing
- salvage treatment
- Volunteers
- 527 people
- Sponsor
- Yanhong Deng
Neoplasm, Hepatic, Pancreatic Neoplasms
Impact of Microparticles on Postoperative Complications in Surgical Patients
Microparticles are cellular fragments which are released actively or passively under conditions of inflammation and stress. The impact of surgical operations on quantity and quality of microparticles remains unknown.
- Conditions
- Neoplasm, Hepatic, Pancreatic Neoplasms, Colorectal Neoplasms
- Trial name
- NCT00677781
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- University of Bern
Colorectal Cancer
Risk Factors for Residual Neoplasia After Endoscopic Mucosal Resection
Laterally Spreading Tumors (LST) are important precursosrs of invasive colorectal cancer. Endoscopic treatment has replaced surgery in most of the cases.
- Trial name
- NCT01478919
- Where
- Czechia
- Volunteers
- 127 people
- Sponsor
- Vitkovice Hospital
ColoRectal Cancer
Community Engaged Colon Cancer Screening Patient Navigator Program
The goal of the project is to increase colorectal cancer screening within the priority population of female and male adults age 50 to 85 in Northern Nevada.
- Trial name
- NCT03031171
- Testing
- Screening patient navigation, Non-Navigated
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Colorectal Cancer
Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, leucovorin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- COPERNICUS (NCT01263171)
- Testing
- Leucovorin, fluorouracil, leucovorin calcium
- Where
- 7 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Cardiff University
Training, Colonoscopy
The Impact of Remote Training on Colonoscopy KPIs
Colonoscopy is a complex, highly operator dependent, practical skill. The consistent attainment of key performance indicators (KPIs) by endoscopists depends primarily upon training.
- Conditions
- Training, Colonoscopy, Colorectal Cancer
- Trial name
- NCT06101836
- Testing
- Training intervention
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- University Hospital, Ghent
Colorectal Cancer
A Study of Avastin (Bevacizumab) and Oxaliplatin Plus Xeloda (Capecitabine) in Patients With Advanced Colorectal Cancer.
This study will assess the efficacy and safety of treatment with the combination Avastin (bevacizumab) 5mg/kg iv every 2 weeks, Xeloda (capecitabine) 1000 mg po b.i.d.
- Trial name
- NCT01159171
- Testing
- bevacizumab [Avastin], capecitabine [Xeloda], oxaliplatin
- Where
- 6 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Hoffmann-La Roche
Liver Metastasis, Colorectal Carcinoma
A Prospective Colorectal Liver Metastasis Database With an Integrated Quality Assurance Program
This prospective database has two main objectives; to evaluate the complication rates, 30-day and 90-day mortality from different surgical strategies for unresectable, borderline resectable or initially unresectable liver…
- Trial name
- CLIMB (NCT02218801)
- Testing
- Evaluation of treatment for liver metastasis
- Where
- 16 sites in Austria, Belgium and 10 more
- Volunteers
- 219 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
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