Clinical trials: Rectal Fistula
Crohn's Disease, Fistula
Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's
The purpose of this study is to determine the safety and feasibility of using allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat people with an ileal pouch anal anastomosis (IPAA) who develop a fistula in the…
- Conditions
- Crohn's Disease, Fistula, Anal Fistula, Pouch, Ileal
- Trial name
- IPAAF (NCT04073472)
- Testing
- mesenchymal stem cells (MSCs)
- Sponsor
- The Cleveland Clinic
Anal Fistula
Ligation of Inter-sphincteric Fistula Tract for Management of Anal Fistula
After abscess formation, an anal fistula is a common consequence, with crypto-glandular infection being the most commonly accepted causative cause.
- Trial name
- NCT05314205
- Testing
- ligation of inter-sphincteric fistula tract
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Anal Fistula
Study of GORE® BIO-A® Fistula Plug for Use in Anal Fistula Repair
Primary outcome variable is healing at the final follow up visit.
- Trial name
- NCT01290666
- Testing
- Fistula Plug
- Volunteers
- 93 people
- Sponsor
- W.L.Gore & Associates
Rectovaginal Fistula, Obstetric Complication
Musset's Surgical Technique: Evaluation of Long-term Results (LONGOMUSSET)
The surgical technique of Musset has shown its effectiveness for the cure of recto-vaginal fistulas. Recto-vaginal fistulas are mostly post-obstetric (88%).
- Trial name
- LONGOMUSSET (NCT05079139)
- Testing
- surgical technique of Musset
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Fistula in Ano, Rectal Fistula
Laser Assisted Treatment of Fistula In Ano
Randomised Controlled Trial comparing Laser assisted closure of transsphincteric fistula to the rectal advancement flap.
- Trial name
- LATFIA (NCT05390151)
- Testing
- Laser treatment of anal fistula, RAF
- Where
- 5 sites in Belgium
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Onset of Perineal Wound Infection
Delayed vs Early Enteral Feeding After Anterior Sagittal Anorectopexy
to study the effect of early vs delayed enteral feeding following ASARP in females with congenital recto-vestibular fistula
- Trial name
- NCT05297916
- Testing
- enteral feeding
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Tanta University
Anal Fistula, Crohn Disease
Stem Cells Treatment of Complex Crohn's Anal Fistula
A pilot study to investigate the safety and feasibility of stem cells treatment of complex anal fistula in patients with Crohn's disease.
- Trial name
- fistula (NCT03466515)
- Testing
- stem cells injection
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Southern Denmark
Hemorrhoids, Anal Fistula
Could Preoperative Assessment of Physical and Psychological Status Help Predict Pain After Anorectal Surgery?
The aim of this single-center prospective observational trial is to study the influence of physical and psychological factors on the intensity of pain syndrome after anorectal interventions and to determine the association…
- Conditions
- Hemorrhoids, Anal Fistula, Anal Fissure, Incontinence
- Trial name
- NCT06049524
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Center of Endourology "Endocenter"
Anal Fistula
Cross-cultural Adaptation of the Chinese Version of QoLAF-Q (Quality of Life in Patients With Anal Fistula Questionnaire) ：A Multi-center Study
The investigators verify the reliability and practicality of the Chinese adaptation results of QoLAF-Q, which helps Chinese doctors better master the methods and techniques of quality of life assessment.
- Trial name
- NCT06962228
- Testing
- Anal fistula surgery
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Anal Fistula
Multicenter Prospective Evaluation of Radiofrequency for Anal Fistulas
Anal fistula treatment is associated with increasing risk of anal incontinence until 40% of cases. New and alternative treatments (glue, advancement flap, plug…) decrease this risk, but with fistula efficacy treatment in 40 to…
- Trial name
- RADIOFIST (NCT03131297)
- Testing
- treatment by radiofrequency
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- F Care Systems NV
Anorectal Fistula
Anal Sphincter Reconstruction After High Recurrent Anorectal Fistula Excision
A retrospective analysis of patients treated for recurrent posterior anorectal fistula, who previously had undergone radical excision of fistula-in-ano, was performed.
- Trial name
- NCT04357210
- Testing
- fistula tract excision and anal sphincter reconstruction
- Volunteers
- 14 people
- Sponsor
- Russian Society of Colorectal Surgeons
Crohn Disease, Anal Fistula
Study on the Treatment of Anal Fistulas Using Alofisel Versus Fat Autologous Stem Cells
One of the newest and most innovative medicinal approaches is cell therapy. Several clinical trials and experimental investigations have looked into the feasibility of treating CD-related fistulas with stem cells.
- Trial name
- CHAZAM (NCT05974280)
- Testing
- Alofisel, Fat stem cell
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Nantes University Hospital
Fistula-in-ano, Draining Wound
A Study Of Cryptoglandular Fistula-in-ano And Associated Non-healing Draining Wounds With Kerecis SurgiClose
The purpose of this study is to determine feasibility of Kerecis intact fish skin for healing of fistula-in-ano and associated non-healing draining wounds.
- Trial name
- NCT07098715
- Testing
- Kerecis fish skin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Anal Fistula
Anal Fistula and Microdialysis - What is Yet to Learn?
Anal Fistula can be a challenging condition to treat. Microdialysis has never before been used to examine the inner environment of anal fistula. This is now going to be performed.
- Trial name
- NCT04178707
- Testing
- OnZurf Probe, Senzime AB, Uppsala, Sweden
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- University Hospital, Umeå
Complex Anal Fistula
Success Rate, Continence, and Quality of Life With a Bioprosthetic Plug for Treating Complex Anal Fistula
Anal abscess-fistula disease is of common occurrence and has a significant impact on the quality of life of affected individuals.
- Trial name
- NCT01612195
- Testing
- Anal fistula plug
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Anal Fistula
Treatment of Transsphicteric Fistula-in-ano by Method of Laser Thermoobliteration(FiLaC™).
This is a randomized, controlled, parallel study to compare the results of treatment for patients with transsphincteric fistulas-in-ano.
- Trial name
- NCT03690934
- Testing
- Fistula-tract laser closure (FiLAC™), Monopolar coagulation of fistulous tract
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Anal Fistula
A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas
The goal of this clinical trial is to assesses the safety of autologous RD2 Ver.02 as compared to a control for managing transsphincteric and intersphinsteric anal fistulas.
- Trial name
- NCT05641844
- Testing
- RD2 Ver.02, Saline
- Where
- 10 sites in United States, Israel
- Volunteers
- 110 people
- Sponsor
- RedDress Ltd.
Fistula in Ano, Ano Fistula
The Impact of 3D Anal Fistula Models on Patient Understanding and Decision Making
An anal fistula is an abnormal communication between the luminal surface of the anorectal canal and the perianal skin. Fistulas can vary in their complexity and can be challenging to treat, due to the anatomical relation to the…
- Trial name
- 3DAF (NCT04069728)
- Testing
- Explanation with 3D printed fistula model, Standard explanation
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Anal Fistula
Treatment of Anal Fistulas Advancement Flap
This study comprises a prospective study of 40 patients with transphincteric anal fistula. The patients were classified into two groups: Group I: Fistulectomy, closure of internal sphincter and rectal advancement flap includes…
- Trial name
- flap (NCT01042821)
- Testing
- partial rectal wall advancement flap, mucosal advancement flap
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University