Clinical trials: Rectal Surgery
LARS - Low Anterior Resection Syndrome, Rectal Cancer Surgery
Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance
The goal of this clinical study is to gain further insights into the treatment of patients with Low Anterior Resection Syndrome (LARS) symptoms after rectal resection.
- Conditions
- LARS - Low Anterior Resection Syndrome, Rectal Cancer Surgery, Rectal Cancer, Quality of Life (QOL)
- Trial name
- iRECOVER (NCT06936774)
- Testing
- Intensified follow-up program
- Where
- 5 sites in Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Wound Healing in Anal Fistula Surgery
Tongyangxiao Lotion for Postoperative Wound Healing After Anal Fistula Surgery
This study tests whether a traditional Chinese herbal bath called Tongyangxiao (TYX) lotion helps surgical wounds heal faster in patients who have had anal fistula surgery.
- Trial name
- NCT07562672
- Testing
- Tongyangxiao (TYX) group, Potassium permanganate (PP) group
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Yongkang An
Rectal Cancer, Surgery
Multicenter Phase II Study of Transanal TME (taTME)
Radical rectal cancer resection, namely total mesorectal excision (TME), is the cornerstone of the treatment of resectable rectal cancer.
- Trial name
- NCT03144765
- Testing
- Transanal Total Mesorectal Excision (taTME)
- Where
- 12 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Middle and Low Rectal Cancer, Rectal Cancer Surgery
Intraoperative Rectal Lavage to Prevent Local Recurrence After Laparoscopic Mid-to-Low Rectal Cancer Resection: A Multicenter Randomized Trial
Brief Summaries Trial Purpose The primary objective of this prospective, randomized, multicenter, open-label, parallel-controlled clinical trial is to evaluate whether intraoperative rectal irrigation during laparoscopic radical…
- Trial name
- TOWER-2 (NCT07512232)
- Testing
- Rectal irrigation
- Where
- China
- Volunteers
- 1,598 people
- Sponsor
- Sun Yat-sen University
Anal Fistula Surgery, Anal Fistula
Recurrence and Anal Fistula Patient Reported Outcomes Trial
Perianal fistulas are a chronic anorectal condition associated with significant morbidity, including pain, persistent discharge, infection, and impaired continence, all of which can substantially affect patients' quality of life.
- Conditions
- Anal Fistula Surgery, Anal Fistula, Perianal Fistula
- Trial name
- RAPPORT (NCT07477496)
- Testing
- Perianal fistula surgical repair
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Anal Fistula Surgery, Anal Fistula
Impact of Surgical Timing on Anal Fistula Outcomes
This study aims to evaluate if the amount of time a person experiences symptoms of an anal fistula before having surgery affects their surgical outcomes and recovery.
- Conditions
- Anal Fistula Surgery, Anal Fistula, Surgery Timing
- Trial name
- NCT07482241
- Volunteers
- 90 people
- Sponsor
- Assiut University
Post-Op Complication, Post Colo- Rectal Surgeries
Core Stability Exercises Versus Tai Chi Exercises on Dynamic Balance After Colo-rectal Surgeries.
Forty patients from both genders, who have undergone colorectal surgeries. Their ages ranged from 25 to 40 years. The participants was selected from El Mataria teaching hospital and randomly distributed into two equal groups.
- Conditions
- Post-Op Complication, Post Colo- Rectal Surgeries, Colo -Rectal Surgeries
- Trial name
- NCT07451444
- Testing
- Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University
Colorectal Cancer (CRC), Rectal Cancer Surgery
Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery
Anastomotic leakage remains a major complication after colorectal cancer surgery. Indocyanine green fluorescence angiography (ICG-FA) allows real-time intraoperative assessment of bowel perfusion; however, its clinical impact…
- Conditions
- Colorectal Cancer (CRC), Rectal Cancer Surgery, Sigmoid Colon Cancer
- Trial name
- NCT07423130
- Where
- Poland
- Volunteers
- 115 people
- Sponsor
- Jagiellonian University
Haemorrhoid, Haemorrhoidal Bleeding
Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty
This prospective cohort study evaluates whether combining "suture mucopexy" (a simple stitch-based lift of prolapsed tissue) with Laser Hemorrhoidoplasty (LHP) can effectively relieve pain, bleeding and prolapse in adults with…
- Conditions
- Haemorrhoid, Haemorrhoidal Bleeding, Anorectal Surgeries, Anorectal Diseases
- Trial name
- HeMuLa (NCT07404774)
- Testing
- Laser Haemorrhoidoplasty and Suture Mucopexy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Rectal Tumors, Tumor of Sigmoid Colon
Effect of Dexmedetomidine on Lung Protection in Elderly Patients Undergoing Laparoscopic Surgery for Colorectal Cancer
The primary change in aging lung tissue among older people is atrophy, leading to a significant decline in ventilatory function.
- Conditions
- Rectal Tumors, Tumor of Sigmoid Colon, Lung Injury, Surgery, Laparoscopic
- Trial name
- Dex (NCT07385898)
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 64 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Natural Orifice Specimen Extraction Surgery, Middle Rectal Cancer
Robotic Natural Orifice Specimen Extraction Surgery Compared to Robotic Assisted Surgery for Median Rectal Cancer
The purpose of this study is to evaluate the short-term outcomes of roboric natural orifice specimen extraction surgery (NOSES-II) compared to conventional assisted robotic surgery in the treatment of median rectal cancer.
- Conditions
- Natural Orifice Specimen Extraction Surgery, Middle Rectal Cancer, Robotic, Short-term Outcomes
- Trial name
- NCT06454201
- Testing
- robotic natural orifice specimen extraction surgery, robotic transabdominal specimen extraction surgery
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanchang University
Rectal Neoplasms, Rectal Neoplasms Malignant
The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer
The goal of this clinical trial is to learn whether a modified single-stapled anastomosis (MST) can reduce anastomotic leakage compared with the conventional double-stapled technique (DST) in adult patients undergoing…
- Conditions
- Rectal Neoplasms, Rectal Neoplasms Malignant, Rectal Cancer, Rectal Cancer Surgery
- Trial name
- MST (NCT07376980)
- Testing
- Modified single-stapled anastomosis technique
- Where
- 6 sites in South Korea
- Volunteers
- 450 people
- Sponsor
- Korea University Anam Hospital
Rectal Cancer Patients, Rectal Cancer Surgery
Postoperative Outcomes of Single-stapled Anastomosis Combined With Transanal Natural Orifice Specimen Extraction
Natural Orifice Specimen Extraction (NOSE) eliminates the need for additional abdominal incisions in minimally invasive colorectal procedures, potentially reducing the risk of wound complications and postoperative pain.
- Trial name
- NOSE (NCT07358247)
- Where
- Italy
- Volunteers
- 190 people
- Sponsor
- Istituto Clinico Humanitas
Adult Patients With Locally Advanced Rectal Cancer Indicated to Neoadjuvant Therapy and Surgery
Postoperative Complications After Neoadjuvant Chemoradiotherapy or Short-course Radiotherapy and Total Neoadjuvant Treatment: a Multicentric Retrospective Cohort Study
The primary objective of the study is to compare the rate of postoperative complications between rectal cancer patients undergoing standard neoadjuvant chemoradiotherapy or short- course radiotherapy and patients receiving TNT.
- Trial name
- POCAT (NCT07346248)
- Testing
- Chemoradiotherapy
- Where
- Italy
- Volunteers
- 266 people
- Sponsor
- Istituto Clinico Humanitas
Anal Fistula, Patient Discharge Education
Determining the Effect of Education Given to Patients Undergoing Outpatient Anal Fistula Surgery
It is emphasized that discharge education should shift from traditional healthcare provider-centered, one-way education to patient-centered education based on patient-care provider interaction to ensure patients' active…
- Conditions
- Anal Fistula, Patient Discharge Education, Outpatient Anal Surgery
- Trial name
- anal fistula (NCT07323160)
- Testing
- Teach-back discharge education
- Volunteers
- 76 people
- Sponsor
- Muğla Sıtkı Koçman University
Colo-rectal Surgery
To Test Effectiveness of Virtual Reality on Post Operative Patients 'VR-RAP@
Virtual reality (VR) headsets (like those used in gaming) allow users to feel immersed in an artificial 3 dimensional environment. The user is able to look around within the environment and interact with it.
- Trial name
- VR-RAP (NCT07274098)
- Testing
- Virtual reality
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Rectal Cancer Surgery
Comparison of Different Surgical Approaches in Female Rectal Cancer.
Mid-to-low rectal cancer exhibits an extremely high incidence rate in China. Currently, the primary treatment approach for mid-to-low rectal cancer remains surgical intervention, with total mesorectal excision (TME) being the…
- Trial name
- NCT07189780
- Testing
- Surgical approach
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Rectal Cancer, Surgery
Blood Flow Path Reconstruction in Rectal Cancer
A total of 89 patients with distal sigmoid and rectal cancer were referred for observation and underwent MS-CTA between June 2020 and March 2022.
- Conditions
- Rectal Cancer, Surgery, Image
- Trial name
- NCT05674097
- Testing
- no intervention
- Where
- China
- Volunteers
- 89 people
- Sponsor
- Shandong First Medical University
General Surgery, Oncology
3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin
This retrospective study aims to develop an AI-assisted 3D modeling system to improve staging accuracy for stage II-III locally advanced rectal cancer (LARC).
- Conditions
- General Surgery, Oncology, Medical Informatics
- Trial name
- NCT07183124
- Testing
- AI-Assisted 3D Imaging Model for Tumor and CRM Assessmen
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- Taichung Veterans General Hospital