Clinical trials: Recurrent Abortion
Recurrent Miscarriage
3D Ultrasound to Assess in Recurrent Miscarriage
This observational study aims to compare the prevalence of acquired abnormalities of the uterus (fibroids, polyps, intrauterine adhesions, adenomyosis) in women who have recurrent miscarriages with the fertile population.
- Trial name
- 3D-ARM (NCT06164015)
- Testing
- 3D Ultrasound scan with power Doppler angiography
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Recurrent Miscarriage, Antiphospholipid Syndrome
Use of Warfarin After the First Trimester in Pregnant Women With APS
Evaluation of shifting to oral vitamin K antagonist after the first trimester instead of using low molecular weight heparin (LMWH) throughout pregnancy in pregnant women with antiphospholipid syndrome (APS)
- Trial name
- NCT02303171
- Testing
- Enoxaparin, Warfarin
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mohamed Sayed Abdelhafez
Recurrent Miscarriage, Infertility
Iron Status in Female Infertility and Recurrent Miscarriage
Multiple studies suggest a link between the iron status and the development of the endometrium. Therefore, a sufficient iron supply seems to relevant for female fertility and reproduction.
- Conditions
- Recurrent Miscarriage, Infertility, Iron-deficiency
- Trial name
- NCT05034250
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Recurrent Miscarriages
Maternal KIR and Fetal HLA-C Genes in Recurrent Miscarriages
For implantation of developing conceptus, placental cells need to invade mother's uterus to access maternal blood supply in a control manner.
- Trial name
- NCT00180804
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Recurrent Spontaneous Abortion
Difference Between Mean Gestational Sac Diameter and Crown-rump Length as a Marker of First-trimester Pregnancy Outcome in Patients With Recurrent Spontaneous Abortion
Objective: To determine the effect and predictive value of the difference between the mean gestational diameter (mGSD) sac and crown-rump length (CRL) of the first trimester on the pregnancy outcomes of patients with recurrent…
- Trial name
- mGSD-CRL& RSA (NCT06081556)
- Testing
- ultrasonic testing
- Where
- China
- Volunteers
- 256 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Recurrent Miscarriage, First Trimester Abortion
Hydroxychloroquine for Prevention of Recurrent Miscarriage.
Recurrent miscarriage (RM) defined by >=3 consecutive losses affects 1% of fertile couples. Most women have recurrent early loss with a failure of development before 10 weeks' gestation.
- Trial name
- BBQ (NCT03165136)
- Testing
- Hydroxychloroquine
- Where
- 18 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Recurrent Early Pregnancy Loss, Thyroid Diseases
Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women
The goal of this clinical trial is to investigate the influence of thyroxine supplementation on pregnancy outcomes in women with varying levels of Thyroid-Stimulating Hormone (TSH), who have experienced recurrent pregnancy loss…
- Trial name
- NCT06036576
- Testing
- Levothyroxine Pill
- Where
- Iraq
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Acupuncture, Recurrent Spontaneous Abortion
The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion
Recurrent spontaneous abortion (RSA) is a common pregnancy complication in women of reproductive age and the cause of RSA remains largely unclear. Acupuncture is widely used in clinical practice to treat infertility and abortion.
- Conditions
- Acupuncture, Recurrent Spontaneous Abortion, Ultrasound Therapy, Coagulation
- Trial name
- NCT05998421
- Testing
- acupuncture, routine aspirin and heparin treatment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Jianmei Xia
Recurrent Miscarriage
Distinct Alterations in Gut Microbiota Composition Among Women of Reproductive Age With Elevated Homocysteine Levels.
The goal of this observational study is to test the alterations of gut microbiota composition among women of reproductive age with elevated homocysteine levels.
- Trial name
- NCT06001060
- Where
- China
- Volunteers
- 38 people
- Sponsor
- First People's Hospital of Hangzhou
Vitamin D Deficiency, Recurrent Spontaneous Abortion
Study on Clinical Value of Vitamin D in Recurrent Spontaneous Abortion
The observational study is to compare vitamin D deficiency and related indicators among different spontaneous abortions in describe female reproductive health.The main question aim to answer is: the possible pathogenesis of…
- Trial name
- NCT06002035
- Testing
- Binom Vitamin D drops
- Where
- China
- Volunteers
- 1,421 people, healthy volunteers welcome
- Sponsor
- Jianmei Xia
Recurrent Miscarriage
Nutritional Deficiency and Recurrent Miscarriage
This prospective cohort study primarily aims to examine the association between blood niacin levels and recurrent miscarriage.
- Trial name
- NCT05267678
- Testing
- No intervention
- Where
- China
- Volunteers
- 499 people
- Sponsor
- Westlake University
Recurrent Spontaneous Abortion
Prospective Study of BMD and Ca-P Metabolism in RSA Patients: LMWH Use Versus Control
The goal of this prospective observational study is to learn about the effect of low molecular weight heparin (LMWH) application on bone mineral density (BMD) and on calcium-phosphorus metabolism in patients with recurrent…
- Trial name
- NCT05878574
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Vitamin D Deficiency, Recurrent Miscarriage
The Cohort Study of the Correlation Between Serum 25(OH)D Level and Pregnancy Outcome
The objective of this single-center prospective observational study is to clarify the trend of maternal serum 25(OH)D levels before pregnancy and during pregnancy, and to explore the correlation between serum 25(OH)D levels and…
- Conditions
- Vitamin D Deficiency, Recurrent Miscarriage, Pregnancy Related
- Trial name
- NCT05824897
- Testing
- Serum levels of vitamin D
- Where
- China
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Recurrent Pregnancy Loss
Association of HY-restricting HLA Class II Alleles, Sex of Firstborn Child, and Pregnancy Outcome in RPL Patients
This cross-sectional and prospective cohort study will investigate if sRPL patients with a first born boy who carry ≥1 HY-restricting (HY-r) HLA class II alleles are associated with a lower chance for a succesful reproductive…
- Trial name
- NCT05342948
- Where
- Denmark
- Volunteers
- 583 people
- Sponsor
- Aalborg University Hospital
Autoimmune Thyroiditis, Recurrent Miscarriage
Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss
The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies.
- Trial name
- NCT05680376
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Zonguldak Bulent Ecevit University
Abortion, Spontaneous, Miscarriage, Recurrent
The Role of Hydrosalpinx in Recurrent Miscarriage
Miscarriage affects one in five pregnancies and little progress has been made in understanding and treating this distressing condition. C. trachomatis is the most common sexually transmitted infection in the UK. C.
- Conditions
- Abortion, Spontaneous, Miscarriage, Recurrent, Hydrosalpinx
- Trial name
- NCT03703401
- Testing
- Hysterosalpingo-contrast-sonogram
- Where
- United Kingdom
- Volunteers
- 137 people
- Sponsor
- University of Birmingham
Miscarriage, Recurrent, Infertility
The Role of NLRP Gene Family (NLRP1~14) in Recurrent Miscarriage and Infertility
Development of mole was not associated with segregation of mutated NLRP7 allele in the haploid oocyte. We hypothesize NLRP7 is a maternal factor involved in regulating early embryo development or embryo-uterine interaction.
- Trial name
- NCT04141618
- Where
- Taiwan
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Recurrent Miscarriage
The Role of Prothrombin Gene and Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphisms as Risk Factors for Recurrent Miscarriage
Recurrent miscarriage is a pregnancy loss before 20 weeks of gestation. The recurrent pregnancy loss(RPL) usually occurring in the first trimester of gestation and its rate is quite high (15-20% even in full reproductive period)…
- Trial name
- NCT03209063
- Testing
- polymerase chain reaction
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Assiut University
Miscarriage, Recurrent
Effects of Co-treatment on Endometrial abv3-integrin Expressions in Women With Recurrent Implantation Failure
To compare the abv3-integrin expression in endometrium tissue among RIF women between the GnRH analogue with Aromatase Inhibitor (Group A) , GnRH analogue with progesterone (Group B) and GnRH analogue alone as control group…
- Trial name
- NCT05437471
- Testing
- GNRH Analoge, Duphaston, Letrozole
- Where
- Malaysia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Infertility Female, Recurrent Miscarriage
Study on the Association Between SXCI and RM and the Possible Genetic Mechanism
To determine whether there is higher incidence of skewed X chromosome inactivation(SXCI) in the recurrent miscarriage(RM) population compared with normal population, and verify the existing hypothesis of the possible genetic…
- Trial name
- NCT02504281
- Where
- China
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute