Clinical trials: Recurrent Abortion
Abortion, Habitual
Pr-conceptional Progesterone for Unexplained Recurrent Miscarriage
In women with unexplained recurrent miscarriages, progesterone (400 mg pessaries, twice daily), started soon as possible at luteal phase and after a positive pregnancy test and continued to 28 weeks of gestation, compared to…
- Trial name
- NCT01670929
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 700 people
- Sponsor
- Woman's Health University Hospital, Egypt
Arcuate Uterus
A Randomised Controlled Trial of Hysteroscopic Resection of Mild Septum/Arcuate Uteri.
At least 82 cases of recurrent miscarriage women with a diagnosis of arcuate uterus, confirmed by three-dimensional intra-vaginal sonography (3D-TVS) and hysteroscopy, will be recruited.
- Trial name
- NCT03384082
- Testing
- hysteroscopic treatment
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Recurrent Pregnancy Loss
Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL
compare uterine artery blood flow before and after the administration of Isosorbide mononitrate as a nitric oxide donor during mid secretory phase of menstrual cycle for patients with unexplained recurrent pregnancy loss.
- Trial name
- NCT05341856
- Testing
- isosorbide mononitrate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Recurrent Pregnancy Loss, Preimplantation Genetic Screening
Live Birth Rate in Patients With Unexplained Recurrent Pregnancy Loss
STUDY AIM: to study the pregnancy outcomes and offspring development of patient with Unexplained Recurrent Pregnancy Loss Treated by PGS and spontaneous pregnancy, and to compare the health economic indicators and patient…
- Trial name
- NCT04621773
- Testing
- Preimplantation Genetic Screening(exposure)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Recurrent Abortion
Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent Abortion
Recent data indicates that 5 methyltetrahydrofolate (5MTHF) can reduce serum homocystein level more efficiently than folic acid.
- Trial name
- NCT01976676
- Testing
- 5-methyltetrahydrofolate, folic Acid
- Volunteers
- 220 people
- Sponsor
- National Nutrition and Food Technology Institute
Induced Abortion
Post Abortion IUD & Recurrent Abortion 2005-2006
The rate of repeat abortions will be lowest in those women who choose immediate insertion of an IUD post-abortion versus those who immediately choose oral contraceptive pills and those who indicate all other contraceptive choices…
- Trial name
- NCT01776957
- Testing
- Device: Intrauterine device (IUD)
- Volunteers
- 1,308 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cerclage, Cervical, Cervical Insufficiency
Long-Term Patient-Reported Maternal Outcomes Following Abdominal Cerclage for the Prevention of Preterm Birth
This study aims to explore the maternal patient reported outcomes on pelvic pain sexual health anxiety and depression bladder discomfort foreign body sensation trust in the cerclage, and how these parameters affect the general…
- Trial name
- NCT06875401
- Testing
- Abdominal cerclage (open or laparoscopic)
- Where
- Denmark
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Insulin Resistance
Insulin Resistance in Recurrent Miscarriage
The objective of this study is to study the association between insulin resistance and recurrent spontaneous miscarriage (RSM).
- Trial name
- IRRM (NCT02705248)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Infertility, Recurrent Implantation Failure
Effect of Reproductive Tract Microbiota on Pregnancy Outcome in IVF/ICSI
A single center，observational cohort study to explore the relationship between reproductive tract microbiota and pregnancy outcome in the patients accepted IVF/ICSI.
- Conditions
- Infertility, Recurrent Implantation Failure, Recurrent Miscarriage
- Trial name
- NCT04293068
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Infertility, Miscarriage, Recurrent
ANXA5 M2 Haplotyping in IVF Patients and Embryos
This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier…
- Conditions
- Infertility, Miscarriage, Recurrent, Pregnancy Complications
- Trial name
- NCT04544462
- Testing
- M2 Test
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Thyroid, Infertility
Thyroid Autoimmunity and Reproductive Failure in Danish Women
The present Ph.D.-study investigates the mechanisms behind the association between thyroid autoimmunity and reproductive failure.
- Conditions
- Thyroid, Infertility, Autoantibodies, Autoimmunity
- Trial name
- NCT02912442
- Where
- Denmark
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Recurrent Pregnancy Loss, Not Pregnant, Recurrent Implantation Failure
Treatment With Prednisone of Women With RPL or RIF Positive to Antithyroid Antibodies and Embryotoxicity Test
In Reproductive Medicine there is a unresolved question, whether thyroid autoimmunity may promote infertility, embryo demise and miscarriage.
- Trial name
- NCT06641440
- Testing
- Prednisone
- Where
- 2 sites in Italy
- Volunteers
- 42 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Recurrent Pregnancy Loss, Early Pregnancy Failure
Ultrasound Predictors of Early Pregnancy Failure in Patients With Recurrent Pregnancy Loss
evaluation of the role of ultrasonographic parameters (mean gestational sac diameter, yolk sac diameter, crown rump length, embryonic heart rate and uterine artery Doppler) in predicting early pregnancy failure in patients with…
- Trial name
- NCT03178682
- Testing
- ultrasound parameters
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Recurrent Pregnancy Loss, Euthyroid With Thyroid Antibodies
Effect of HCQ Combined With LT4 on LBR in Euthyroid Women With URPL and TPO-Ab
The goal of this clinical trial is to learn if combined treatment of levothyroxine and hydroxychloroquine would improve the live birth of euthyroid women with thyroid peroxidase antibodies and unexplained recurrent pregnancy…
- Trial name
- QT-LIFE (NCT06652113)
- Testing
- hydroxychloroquine and levothyroxine, Levothyroxine
- Where
- 2 sites in China
- Volunteers
- 796 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Abortion, Habitual
Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia
The prevalence of insulin resistance is increased in women with recurrent miscarriage compared with matched fertile controls,Insulin resistance (IR) in this syndrome is not only implicated toward early pregnancy loss (EPL) but…
- Trial name
- MetRPL (NCT01718340)
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Recurrent Pregnancy Loss(RPL), Recurrent Miscarriage
Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss
For many years there is a lack of large randomized controlled trials that study the effect of low dose prednisone in women with RPL and thus the evidence of a probable efficacy of prednisone in RPL women remains limited and…
- Trial name
- NCT04558268
- Testing
- Prednisone, Progesterone, vit D
- Where
- Israel
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Recurrent Abortion
Low-molecular-weight Heparin (LMWH) Versus Unfractionated Heparin (UFH) in Pregnant Women With Recurrent Abortion Secondary to Antiphospholipid Syndrome
The aim of this study is to compare the efficacy and safety of Low molecular weight heparin (LMWH) plus low dose aspirin (LDA) with unfractionated heparin(UFH) plus LDA in women with recurrent pregnancy loss associated with…
- Trial name
- NCT01051778
- Testing
- enoxaparin 40mg plus low dose aspirin, Heparin calcium5,000 U twice daily plus low dose aspirin
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Recurrent Miscarriage
The Role of Prothrombin Gene and Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphisms as Risk Factors for Recurrent Miscarriage
Recurrent miscarriage is a pregnancy loss before 20 weeks of gestation. The recurrent pregnancy loss(RPL) usually occurring in the first trimester of gestation and its rate is quite high (15-20% even in full reproductive period)…
- Trial name
- NCT03209063
- Testing
- polymerase chain reaction
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility, Recurrent Pregnancy Loss
TNFα and MFG-E8: Novel Biomarkers to Predict Implantation Failure
Question: Can implantation failure (IF) be predicted prior to in vitro fertilization (IVF)? A pilot, non-interventional, clinical study Prospective, controlled, cohort study
- Trial name
- NCT02386384
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Recurrent Miscarriage
Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage
The aim of the study is to estimate the incidence of CE, evaluate the endometrial microorganism of CE, and investigate the therapeutic benefits of antibiotics for women with unexplained recurrent miscarriage and CE.
- Trial name
- NCT06163092
- Where
- Hong Kong
- Volunteers
- 175 people
- Sponsor
- Chinese University of Hong Kong