Clinical trials: Recurrent Aphthous Stomatitis, active
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model
This study aims to improve how oral mucosal disorders-such as oral lichen planus, recurrent aphthous stomatitis, burning mouth syndrome, herpes viral infection and oral candidiasis-are treated in dental settings.
- Conditions
- Oral Lichen Planus, Recurrent Aphthous Stomatitis, Burning Mouth Syndrome, Oral Candidiasis
- Trial name
- NCT07721090
- Testing
- Pharmacist-Led Prescribing Optimization and Patient Counselling
- Volunteers
- 336 people
- Sponsor
- University of Fujairah
Recurrent Aphtous Stomatitis
Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis
The objective of the study is to assess the superiority of apremilast in comparison with placebo to achieve Complete Remission (CR) of oral ulcers at Week 12, in patients with severe Recurrent aphtous stomatitis resistant or…
- Trial name
- PREMS (NCT04227314)
- Testing
- Apremilast
- Where
- 21 sites in France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Rouen
Apthous Ulcer
Recurrent Aphthous Stomatitis Management in Children Using Diode Laser 980 Nanometer Versus Hyaluronic Acid Gel (RCT)
Thirty children with recurrent apthous ulcer will be divided into 3 groups of different treatment modalities to assess their effect on pain, ulcer size, healing and postoperative pain
- Trial name
- RCT (NCT07922681)
- Testing
- laser therapy, Hyaluronic acid group, Negative control group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Recurrent Aphthous Stomatitis
Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Recurrent Aphthous Stomatitis
Bromelain, a natural product, exhibits anti-inflammatory, immunomodulatory, and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored.
- Trial name
- NCT06993337
- Testing
- 35% Topical Bromelain in Orabase, 50% Topical Bromelain in Orabase, 0.1% Topical Triamcinolone Acetonide in Orabase
- Volunteers
- 63 people
- Sponsor
- Cairo University
Recurrent Aphthous Stomatitis, Mouth Ulcer
The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa
This is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the efficacy and safety of spirulina supplementation in patients with radiation-induced oral mucositis (RIOM) receiving…
- Trial name
- NCT07723612
- Testing
- Spirulina Tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Recurrent Aphthous Stomatitis
Sesame Paste for Recurrent Aphthous Stomatitis
Oral recurrent aphthous stomatitis is a painful oral condition that affects large number of patients. In the Middle East, patients tend to commonly manage it by sesame paste.
- Trial name
- NCT07853326
- Testing
- Sesame paste
- Volunteers
- 46 people
- Sponsor
- Ayat Gamal-AbdelNaser
Recurrent Aphthous Stomatitis, Aphthous Ulcer
Salivary E-cadherin, Calprotectin, and Matrix Metalloproteinase-9 Levels in Recurrent Aphthous Stomatitis
The goal of this observational cross-sectional study is to determine the salivary levels of E-cadherin, Calprotectin, and Matrix Metalloproteinase-9 (MMP-9) in patients with Recurrent Aphthous Stomatitis (RAS) and to compare them…
- Trial name
- NCT07141758
- Testing
- ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Selin Yeşiltepe
Trisomy 8 Mosaicism, Trisomy 8 Associated Autoinflammatory Disease
Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders
Background: Trisomy 8 mosaicism is a genetic disorder that can increase inflammation in the body. Symptoms include fevers; sores or ulcers in the mouth, digestive tract, or genital area; skin rashes; problems in organs or…
- Conditions
- Trisomy 8 Mosaicism, Trisomy 8 Associated Autoinflammatory Disease, Mucosal Ulcerations
- Trial name
- NCT07683104
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)