Clinical trials: Recurrent Hernia
Inguinal Hernia
Safety and Effectiveness of Optomesh 3D for Inguinal Hernia Repair
OPTIMUS is an observational study assessing the safety and effectiveness of Optomesh 3D, a shaped surgical mesh used in planned keyhole surgery for a groin (inguinal) hernia.
- Trial name
- OPTIMUS (NCT07836179)
- Testing
- Optomesh 3D
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Swissmed Hospital
Migration of Implant, Pain
Does the Mesh Have to be Fixed in Laparoscopic eTEP Repair of Inguinal Hernia?
Inguinal hernia surgery is one of the most frequently performed procedures among general surgery cases. As with many open surgical methods, this repair is also performed laparoscopically.
- Conditions
- Migration of Implant, Pain, Postoperative Complications, Relapse
- Trial name
- NCT06070142
- Testing
- TEP Group, eTEP Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mehmet Eşref Ulutaş
Ventral Hernia Midline
The Effect of Sutures Versus Mesh in Umbilical Hernia Repair
Background Mesh repair reduces the risk of reoperation for recurrence in patients with small umbilical and epigastric hernias compared with sutured repair.
- Trial name
- ABSNOME (NCT01635868)
- Where
- Denmark
- Volunteers
- 1,313 people
- Sponsor
- Hvidovre University Hospital
Hernia, Hernia, Ventral
Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia
The purpose of RECOVER is to evaluate the performance and safety of Transorb™ self-gripping resorbable mesh in high-risk subjects (at least one risk factor impairing wound healing) when used for reinforcement of abdominal wall…
- Conditions
- Hernia, Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
- Trial name
- RECOVER (NCT06449378)
- Testing
- Transorb™ Self-Gripping Resorbable Mesh
- Where
- 13 sites in United States, Belgium and 1 more
- Volunteers
- 163 people
- Sponsor
- Medtronic - MITG
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Intervertebral Disc Herniation
Preoperative Estimation Of Disc Herniation Recurrence In Patients With Lumbar Disc Herniation
This study will be conducted at Research Institute of Traumatology and Orthopedics (NRITO) n.a. Ya.L.Tsivyan, Novosibirsk, Russia.
- Trial name
- NCT04254250
- Testing
- Preoperative risk estimation of disc herniation recurrence
- Where
- 2 sites in Russia
- Volunteers
- 386 people
- Sponsor
- Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan
Incisional Hernia
Mini- or Less-Open Sublay Operation (MILOS) of Incisional Hernias
Prospective non-randomized observational register study of all elective symptomatic incisional hernias operated on in the Hernia Center of Reference of Gross Sand Hospital using the novel endoscopic assisted Mini- or Less-Open…
- Trial name
- NCT03133000
- Volunteers
- 615 people
- Sponsor
- Gross Sand Hospital
Ventral Hernia, Recurrent Ventral Hernia
Recurrence and Patient Satisfaction After Laparoscopic Hernia Repair With Intraperitoneal Onlay-mesh (IPOM)
For laparoscopic ventral hernia repair, the technique to close the hernia gap is not well established. Mainly three techniques are currently applied: no closure at all extracorporal suturing of the gap intracorporal suturing of…
- Trial name
- SGChirIPOM (NCT01839942)
- Testing
- hernia gap closure, extracorporal suturing of gap
- Where
- Switzerland
- Volunteers
- 348 people
- Sponsor
- Cantonal Hospital of St. Gallen
Incisional Hernia, Ventral Hernia
Risk Factors for Mesh Infection After Abdominal Wall Reconstruction
Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging…
- Conditions
- Incisional Hernia, Ventral Hernia, Parastomal Hernia, Abdominal Wall Defect
- Trial name
- NCT07725718
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Minia University
Hernia, Abdominal, Recurrence
Nationwide Long-term Outcome Surveillance of Physiomesh® vs. Other Meshes in Laparoscopic Incisional Hernia Repair
The primary aim of the present study was to show how a national clinical register combined with other nationwide administrative registers may serve as a tool for pre- and post-marketing evaluation of new mesh and mesh fixation…
- Conditions
- Hernia, Abdominal, Recurrence, Postoperative Complications
- Trial name
- NCT03846661
- Testing
- Physiomesh
- Where
- Denmark
- Volunteers
- 3,338 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Inguinal Hernia
A Multi-site Trial Comparing Lichtensteins Operation and Prolene Hernia System in Inguinal HErnia Repair
Patients with a primary unilateral inguinal hernia are randomized to Lichtenstein's operation or Prolene Hernia System to repair their groin hernia. Follow up for three years with a total number of 4 clinical examinations.
- Trial name
- NCT00184483
- Testing
- Lichtenstein's operation, Prolene Hernia System
- Where
- Norway
- Volunteers
- 405 people
- Sponsor
- Norwegian University of Science and Technology
Hernia, Inguinal, Postoperative Pain
Comparison of Hernia Sac Ligation Versus Invagination
Management of indirect hernial sac in inguinal hernia repairs has long been a subject of debate among general surgeons. Although hernial sac high ligation (HL) is a time-honored concept in groin hernia surgery…
- Conditions
- Hernia, Inguinal, Postoperative Pain, Recurrence
- Trial name
- NCT05308251
- Testing
- Lichtenstein Mesh Hernioplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Samsun Education and Research Hospital
Ventral Hernia
Longitudinal Relaxing Incision as a Technique for Recurrence Prevention in Ventral Hernia
The aim of the study is showing the efficiency of using Longitudinal relaxing incision as a Technique for recurrence prevention in Ventral Hernia
- Trial name
- NCT05526209
- Testing
- using longitudinal relaxing incision as a technique for recurrence prevention in ventral hernia
- Volunteers
- 40 people
- Sponsor
- Assiut University
Inguinal Hernia, Indirect, Surgery
Laparoscopic High-Ligation Repair of Indirect Inguinal Hernias in Adults
Inguinal hernia surgery has undergone significant and extensive transformation, including the advent of tissue-based repairs and later, tension-free repairs with the acceptance of prosthetic mesh.
- Conditions
- Inguinal Hernia, Indirect, Surgery, Postoperative Pain, Recurrence
- Trial name
- NCT06120114
- Testing
- Modified percutaneous internal ring suturing
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Parastomal Hernia
Risk Factors for Morbidity After Parastomal Hernia Repair
The Danish Ventral Hernia Database (DVHD) registers 37 different perioperative parameters. The aim of present study is to use large-scale data from DVHD to uncover risk factors for readmission, reoperation (any indication), death…
- Trial name
- PAHEREP (NCT01484743)
- Testing
- differences in surgical techniques
- Where
- Denmark
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Inguinal Hernia, Adult
Comparison of Self Fixating Mesh to Mesh Fixation With Metallic Tacks in Laparoscopic Inguinal Hernia Repair
This study compares the use of self-fixating mesh to mesh fixation with tackers in the management of inguinal hernia by laparoscopic method.
- Trial name
- SELFITAC (NCT03564535)
- Testing
- Self fixating group, Tacker fixation group
- Where
- India
- Volunteers
- 112 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Physical Function, Pain
Polypropylene Mesh Versus Polytetrafluoroethylene (PTFE) Mesh in Inguinal Hernia Repair
To evaluate the safety and efficacy of the Lichtenstein's hernioplasty using Infinit® PTFE Mesh, and to compare it with the traditional Lichtenstein procedure performed with polypropylene mesh.
- Conditions
- Physical Function, Pain, Hernia, Wound Infection
- Trial name
- NCT01141335
- Testing
- polypropylene mesh, Infinit® PTFE mesh (WL Gore)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Roma La Sapienza
Chronic Pain, Recurrences
Comparison of Three Meshes in Lichtenstein Hernia Repair
Chronic pain may be a long-term problem after inguinal Lichtenstein hernioplasty. The aim of this study was to compare long-term results of hernioplasty using three different meshes (partly absorbable, lightweight polypropylene…
- Trial name
- Lichtenstein (NCT01295437)
- Testing
- Vypro II mesh, Premilene LP, Premilene mesh
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Hernia, Inguinal, Recurrence
Long-term Follow-up After Laparoscopic Inguinal Hernia Repair Using Tisseel for Mesh Fixation
In hernia repair a mesh is used to close the defect in the abdominal wall. This mesh is either secured with tissue penetrating devices (ex. staples,tacks or sutures) or fibrin glue (Tisseel/Tissucol) or left unfixated.
- Conditions
- Hernia, Inguinal, Recurrence, Chronic Pain
- Trial name
- NCT01597011
- Testing
- Fibrin Sealant, Tissue-penetrating mesh-fixation
- Where
- Denmark
- Volunteers
- 2,340 people
- Sponsor
- Herlev Hospital