Clinical trials: Recurrent Ischemic Stroke
Ischemic Stroke
REcurrent Stroke Prevention Through Personalized Education by Clinical Trainers (RESPPECT Trial)
This a single blind randomized control study comparing standard of care for nursing hospital discharge education versus same with an additional experimental enhanced educational intervention.
- Trial name
- RESPPECT (NCT03861494)
- Testing
- Enhanced Stroke Education, Usual Stroke Education
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Washington Regional Medical Center
Ischemic Stroke, Digital Health
Prevention of Ischemic Stroke Recurrence Using Digital Technology Application
The goal of this study is to find out whether a comprehensive management program that uses a smart bracelet and a mobile app can help people who have had an ischemic stroke (a type of stroke caused by a blocked blood vessel in…
- Trial name
- DESIRE (NCT07825311)
- Testing
- Digital Prevention Management, Usual Stroke Secondary Prevention Management
- Where
- China
- Volunteers
- 1,696 people
- Sponsor
- Affiliated Hospital of Nantong University
Stroke, Acute Cerebrovascular Accident
Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times.
- Conditions
- Stroke, Acute Cerebrovascular Accident, Transient Ischemic Attack, Death
- Trial name
- NCT06253000
- Testing
- Cryoablation, Radiofrequency ablation
- Where
- Russia
- Volunteers
- 158 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Stroke, Ischemic, Periodontitis
Periodontal Treatment and Ischemic Stroke
A bulk of observational evidence suggests an association between periodontitis and recurrent vascular events in ischemic stroke survivors.
- Trial name
- NCT04956211
- Testing
- Periodontal therapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Santiago de Compostela
Acute Ischemic Stroke
An Application Provides Personalized Suggestions Based on Secondary Prevention Risk Factors to Stroke Patients
This study applied an application that provides personalized suggestions and explore the effect of this actual intervention on reducing the risk of stroke recurrence
- Trial name
- NCT07098143
- Testing
- Risk factor management
- Volunteers
- 5,092 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Stroke, Patent Foramen Ovale
Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence
A patent foramen ovale (PFO) is found more frequently in patients with an ischemic stroke than in control subjects. Therapeutic options to prevent stroke recurrence include antiplatelet drugs, oral anticoagulants, and…
- Conditions
- Ischemic Stroke, Patent Foramen Ovale, Atrial Septal Aneurysm, Migraine
- Trial name
- CLOSE (NCT00562289)
- Testing
- aspirin, Antivitamins K or rivaroxaban or dabigatran or apixaban, Devices for PFO closure
- Where
- France
- Volunteers
- 664 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Cardiovascular Diseases
MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central Norway
Annually 13000 Norwegians experience an ischemic stroke. The number of stroke is anticipated to increase with 50% within 2030 due to a growing number of elderly.
- Conditions
- Stroke, Cardiovascular Diseases, Cardiovascular Risk Factor, Brain Ischemia
- Trial name
- NCT03962127
- Testing
- no intervention
- Where
- 8 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Norwegian University of Science and Technology
Cerebrovascular Accident, Transient Ischemic Attack
E-Selectin Nasal Spray to Prevent Stroke Recurrence
This study will test the safety and effectiveness of a protein called E-selectin, given as a nasal spray, in preventing the formation of blood clots that can cause stroke.
- Trial name
- NCT00012454
- Testing
- E-Selectin nasal spray
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Acute Ischemic Stroke, Cancer
A Prospective Study to Observe Clinical Outcomes in Patients Receiving Antiplatelet or Anticoagulant Therapy for Cancer-Associated Acute Ischemic Stroke
The goal of this observational study is to learn about the effectiveness and safety of antiplatelet and anticoagulant treatments in people with a history of cancer who have acute ischemic stroke.
- Trial name
- NCT07845903
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute, Atrial Fibrillation
RELAXED: Recurrent Embolism Lessened by Rivaroxaban for Acute Ischemic Stroke
Early recurrence of cardioembolic stroke in patients with atrial fibrillation is common, reaching approximately 6% within 30 days after initial stroke.
- Trial name
- RELAXED (NCT02129920)
- Testing
- This is an observational study
- Where
- Japan
- Volunteers
- 2,000 people
- Sponsor
- Japan Cardiovascular Research Foundation
Acute Ischemic Stroke, Stroke Recrudescence
Multilevel System Intervention Based on Information Platform to Reduce Ischemic Stroke Recurrence Rate
A prospective, multicenter and cluster randomised controlled trial will be conducted, using hospital as randomisation unit. Hospitals in Zhejiang Province, China, will be randomised into two arms (1:1): an intervention arm and a…
- Conditions
- Acute Ischemic Stroke, Stroke Recrudescence, Quality Improvement
- Trial name
- NCT05852080
- Testing
- multilevel system intervention based on information platform
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Acute
ERILs Und SNILs Unter SOC
1. How many ERILs occur in caucasian patients with LAA stroke during 7 days on standard treatment? 2. How many SNILs occur between 7 and 30 days after acute ischemic event on standard treatment? 3.
- Trial name
- NCT05786170
- Testing
- diffusion-weighted magnetic resonance imaging
- Sponsor
- Medical University of Vienna
Embolic Stroke
Shuxuetong for Prevention of Recurrence in Acute Cerebrovascular Events With Embolism
This is a randomized, double blind, placebo-controlled, parallel, multicenter research in order to evaluate the effect of Shuxuetong injection in prevention of symptomatic or asymptomatic new cerebral infarction within 10 days.
- Trial name
- SPACE (NCT03090113)
- Testing
- Shuxuetong Injection
- Where
- 48 sites in China
- Volunteers
- 2,416 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Infarction
Post-marketing Study of Cilostazol (Cilostazol Stroke Prevention Study 2)
The purpose of this study is to investigate the efficacy of cilostazol in preventing recurrence of cerebral infarction and the safety of long-term administration of the drug (100 mg, twice daily) in patients with cerebral…
- Trial name
- NCT00234065
- Testing
- Cilostazol, Aspirin
- Where
- Japan
- Volunteers
- 2,800 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Patent Foramen Ovale, Cryptogenic Stroke
Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure
Patent foramen ovale PFO closure has been shown to reduce the risk of stroke in patients with recurrent stroke. However, the majority of existing clinical studies in this field excluded patients over the age of 60 years.
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke, Older Patients, Medical Treatment
- Trial name
- STOP (NCT05907694)
- Testing
- Transcatheter PFO closure, Optimal medical treatment
- Where
- 2 sites in Canada
- Volunteers
- 714 people
- Sponsor
- Josep Rodes-Cabau
Mini-Stroke
Intensified Secondary Prevention Intending a Reduction of Recurrent Events in TIA and Minor Stroke Patients
Patients after TIA or Stroke are at high risk of experiencing a new stroke or myocardial infarction. Poor adherence to evidence based secondary prevention regimens is frequently seen.
- Trial name
- INSPiRE-TMS (NCT01586702)
- Testing
- Patient centered structured support program
- Where
- Germany
- Volunteers
- 2,082 people
- Sponsor
- Charite University, Berlin, Germany
Stroke Recurrence, Cardiovascular Events
Post-stroke Depression Treatment Effect on Stroke Recurrence
It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.
- Conditions
- Stroke Recurrence, Cardiovascular Events, Depression
- Trial name
- STROKE (NCT04776226)
- Testing
- Citalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 1,230 people
- Sponsor
- Ege University
Ischemic Stroke, TIA
Probucol for Symptomatic Intracranial and Extracranial Artery Stenosis
This study is a multicenter, double-blind, placebo-controlled, randomized clinical trial that aims to evaluate the efficacy of probucol on the reduction of the risk of recurrent stroke in patients with symptomatic intracranial or…
- Trial name
- NCT06225752
- Testing
- Probucol
- Where
- China
- Volunteers
- 5,452 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Stroke, Ischemic
Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial
The overall aim of this research is to improve secondary stroke prevention for older patients with stroke. In current practice, patients with stroke are often prescribed antiplatelet therapy with either aspirin or clopidogrel to…
- Trial name
- STROKE75+ (NCT07454707)
- Testing
- Edoxaban 15 mg, Aspirin or clopidogrel
- Where
- Canada
- Volunteers
- 1,204 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ischemic Stroke, Transient Ischemic Attack
European Blood Pressure Intensive Control After Stroke
Stroke is the third most common cause of death worldwide and the leading cause of disability. High blood pressure is an important risk factor for stroke.
- Trial name
- EPICS-Pilot (NCT04647292)
- Testing
- anti-hypertensive, home blood pressure measurement, telemonitoring and medication titration, Standard of Care Blood Pressure Management with Antihypertensives
- Where
- Ireland
- Volunteers
- 142 people
- Sponsor
- University College Dublin