Clinical trials: Recurrent Persistent Atrial Fibrillation
Atrial Fibrillation Ablation, Persistent Atrial Fibrillation
Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation
The goal of this clinical trial is to determine whether tirzepatide can reduce atrial fibrillation (AF) burden after catheter ablation in overweight or obese patients with persistent AF.
- Conditions
- Atrial Fibrillation Ablation, Persistent Atrial Fibrillation, Obesity & Overweight
- Trial name
- TREAT-AF (NCT07382024)
- Testing
- Tirzepatide, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation, Catheter Ablation
Efficacy of Pulmonary Vein Isolation Alone in Patients With Persistent Atrial Fibrillation
This study examines non-inferiority of pulmonary vein isolation (PVI) for persistent atrial fibrillation (AF) to extensive ablation; and reveals the effect of the presence or origin of AF trigger on outcomes of catheter ablation.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Recurrence
- Trial name
- EARNEST-PVI (NCT03514693)
- Testing
- PVI, PVI plus additional ablation
- Volunteers
- 512 people
- Sponsor
- Osaka Cardiovascular Conference
Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation
Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial Fibrillation
The NEXT PULSE study is a pre-market, prospective, multi-center, non-randomized, interventional clinical study. Adult subjects with symptomatic paroxysmal or persistent AF who provided consent will be enrolled and treated with…
- Trial name
- NEXT PULSE (NCT07575828)
- Testing
- PulseSelect Pulse Field Ablation (PFA) System
- Volunteers
- 320 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Persistent Atrial Fibrillation
Renal Denervation Combined With Pulsed Field Ablation to Prevent Recurrence in Persistent Atrial Fibrillation
The goal of this clinical trial is to learn whether adding renal denervation (RDN) to pulsed-field ablation (PFA) reduces recurrence of atrial tachyarrhythmias in adults (≥18 years) with persistent atrial fibrillation undergoing…
- Trial name
- OFF-MED (NCT07320768)
- Testing
- renal denervation, Pulsed-Field Ablation (PFA)
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation
Use of Volta Medical AI-software During Atrial Fibrillation Ablation to Identify Patients Who May Need More Than Pulmonary Vein Isolation.
DISPLAY-AF is a prospective, multicenter, single-arm post-market clinical follow-up investigation designed to evaluate whether spatiotemporal dispersion areas identified by the Volta AF-Xplorer II artificial intelligence (AI)…
- Trial name
- DISPLAY-AF (NCT07807423)
- Testing
- Complete biatrial mapping
- Where
- 5 sites in France
- Volunteers
- 125 people
- Sponsor
- Volta Medical
Atrial Fibrillation
The Use of DIOVAN to Reduce Post-Cardioversion Recurrence of Atrial Fibrillation Trial (the DRAFT Trial)
24 week, single center, prospective, randomized, double-blind treatment study of valsartan (80 mg/bid, increased to 160 mg/bid) or placebo in addition to other general medical therapy in patients with persistent atrial…
- Trial name
- NCT00343499
- Testing
- valsartan
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Intermountain Health Care, Inc.
Persistent Atrial Fibrillation
Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation Ablation
This prospective, randomized, single-center study will compare sevoflurane inhalational anesthesia with propofol intravenous anesthesia in patients undergoing intracardiac echocardiography-guided radiofrequency catheter ablation…
- Trial name
- NCT07877116
- Testing
- Sevoflurane, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Hüseyin Ulaş Pinar
Persistent Atrial Fibrillation, Long-standing Persistent Atrial Fibrillation
Pulmonary Vein Antrum Isolation (PVAI) Plus Scar Homogenization and Non-PV Triggers Ensure Long-term Recurrence-free Survival in Non-paroxysmal Atrial Fibrillation
This study aims to examine the long-term success rate of catheter ablation in non-paroxysmal atrial fibrillation patients using different ablation strategies such as : (i) pulmonary vein antrum isolation (PVAI) + isolation of…
- Trial name
- TANTRA (NCT01672138)
- Testing
- Pulmonary Vein Antrum Isolation, scar homogenization, Non-PV triggers ablation
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation