Clinical trials: Recurrent Pregnancy Loss
Recurrent Pregnancy Loss
Tender Loving Care for Recurrent Pregnancy Loss
The goal of this investigational study is to evaluate participation in a weekly, interactive, tender loving care messaging platform impact on pregnancy outcomes in patients with recurrent pregnancy loss.
- Trial name
- NCT06182878
- Testing
- Tender loving care intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Infertility and Miscarriage
A Multicenter, Prospective, Randomized, Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on the Natural Pregnancy Outcomes in Patients With Non-recurrent Spontaneous Abortion
The study aims to compare the effects of transcervical resection of septa (TCRS) and expectant management on the natural pregnancy outcomes of patients with septate uterus without recurrent abortion, also covering the treatment…
- Trial name
- NCT07039097
- Testing
- Transcervical resection of septum
- Where
- China
- Volunteers
- 418 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Preeclampsia, Premature Birth
Cohort Study on the Levels of Placental Growth Factor and Nucleosomes in Early Pregnancy and Adverse Pregnancy Outcomes
Objective: This study aims to investigate the association between maternal serum placental growth factor (PLGF) and nucleosome levels in early pregnancy and adverse pregnancy outcomes, and to evaluate their predictive value for…
- Conditions
- Preeclampsia, Premature Birth, Fetal Growth Restriction, Recurrent Miscarriage
- Trial name
- NCT07841197
- Testing
- Measurement of plasma nucleosome and placental growth factor (PLGF) levels
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Habitual Abortion
Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual Abortion
1 % of all pregnancies end in habitual/recurrent abortion. In about half of women with habitual abortions (HAB) hereditary or acquired (antiphospholipid antibodies) thrombophilia are observed.
- Trial name
- HABENOX (NCT00959621)
- Testing
- Aspirin, Klexane, Klexane and ASA
- Where
- Finland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Recurrent Pregnancy Loss
Prospective Recurrent Pregnancy Loss Registry
The purpose of this Registry is to prospectively collect data of Recurrent Pregnancy Loss (RPL) patients attending the specialized care centre at the BC Women's Hospital, in order to evaluate investigation practices, treatment…
- Trial name
- NCT05989178
- Testing
- Data Registry
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- University of British Columbia
Abortion, Habitual, Infertility Unexplained
Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History
The aim of this study is preliminary exploration of the effectiveness and duration of autologous decidual-like NK cells therapy in improving uterine NK cells dysfunction.
- Conditions
- Abortion, Habitual, Infertility Unexplained, Embryo Implantation, Pre-Eclampsia
- Trial name
- NCT06821685
- Testing
- autologous decidual-like NK cells
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Abortion, Habitual
Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage
The definition of recurrent spontaneous abortion (RSA) has changed over the years, and most societies now advocate defining RSA as two or three consecutive or discontinuous miscarriages with the same sexual partner before 24…
- Trial name
- microRNA410 (NCT05658445)
- Testing
- evacuation
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Assiut University
Recurrent Pregnancy Loss
Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) defined as 3 or more pregnancy losses affects approximately 3% of couples trying to achieve parenthood.
- Trial name
- NCT03305263
- Testing
- Hydroxychloroquine
- Where
- Denmark
- Volunteers
- 186 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Abortion, Spontaneous, Abortion, Habitual
RPL: Interval to Live Birth and Adverse Perinatal Outcomes
This will be a retrospective observational cohort study utilizing the data from the British Columbia Perinatal Data Registry (BCPDR).
- Conditions
- Abortion, Spontaneous, Abortion, Habitual, Birth Intervals, Pregnancy Loss
- Trial name
- NCT04360564
- Testing
- Recurrent pregnancy loss
- Where
- Canada
- Volunteers
- 140,000 people, healthy volunteers welcome
- Sponsor
- Children's & Women's Health Centre of British Columbia
Recurrent Pregnancy Losses
The Role of Uterine NK Cells and T Cell Cytokines in Recurrent Miscarriage
The aim of the study is to evaluate the role of uterine natural killer cell(uNK)in recurrent pregnancy losses and the correlation between the numbers of it and embryo toxicity by measuring the level of the Th2 cytokines in normal…
- Trial name
- NCT01688284
- Testing
- office hysteroscopy
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Chromosome Translocation, Genetic Disorders in Pregnancy
Investigation and Diagnosis of the Chromosome Variation in Donated/abandoned Blastocyst
Blastocysts derived from patients seeking infertility treatment were generated by in vitro fertilization and embryo culture as previously described, and were evaluated using the Gardner system.
- Conditions
- Chromosome Translocation, Genetic Disorders in Pregnancy, Recurrent Miscarriage
- Trial name
- NCT05216068
- Testing
- NGS
- Where
- Taiwan
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Acupuncture, Recurrent Spontaneous Abortion
The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion
Recurrent spontaneous abortion (RSA) is a common pregnancy complication in women of reproductive age and the cause of RSA remains largely unclear. Acupuncture is widely used in clinical practice to treat infertility and abortion.
- Conditions
- Acupuncture, Recurrent Spontaneous Abortion, Ultrasound Therapy, Coagulation
- Trial name
- NCT05998421
- Testing
- acupuncture, routine aspirin and heparin treatment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Jianmei Xia
Normal Endometrial Physiology
Endometrial Basis for Infertility in Women With Recurrent Implantation Failure and Pregnancy Loss
Background: Pregnancy loss is the most common complication of pregnancy. It occurs in roughly one-half of natural conceptions. It most frequently occurs in the first 2 to 3 weeks of pregnancy.
- Trial name
- NCT04939064
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recurrent Abortion
Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent Abortion
Recent data indicates that 5 methyltetrahydrofolate (5MTHF) can reduce serum homocystein level more efficiently than folic acid.
- Trial name
- NCT01976676
- Testing
- 5-methyltetrahydrofolate, folic Acid
- Volunteers
- 220 people
- Sponsor
- National Nutrition and Food Technology Institute
Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
A low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including…
- Conditions
- Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss, Recurrent Implantation Failure, Infertility
- Trial name
- NCT05169541
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aalborg University Hospital
Pregnancy, Miscarriage
Aspirin, Heparin and Miscarriage
Efficacy of low dose aspirin (LDA) versus LDA plus low-molecular-weight-heparin (LMWH) in patients with a history of recurrent miscarriages.
- Trial name
- NCT01917799
- Testing
- Aspirin, Heparin
- Where
- Libya
- Volunteers
- 150 people
- Sponsor
- University of Khartoum
Recurrent Pregnancy Loss
Effect of Sildenafil Citrate on Mid Luteal Phase Uterine Artery Blood Flow in Patients With Recurrent Pregnancy Loss
Patients with recurrent pregnancy loss are known to have decreased uterine artery blood flow. Nitric oxide plays a major role in increasing uterine blood flow during the luteal phase.
- Trial name
- NCT04718233
- Testing
- Sildenafil 25Mg Tablet
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Recurrent Pregnancy Loss
SCUBE-1 and Carotid Intima Media Thickness in Recurrent Pregnancy Loss
Clinical research will be carried out on two groups of patients. It will be performed on people with recurrent pregnancy loss and without a history of pregnancy loss.
- Trial name
- NCT04397042
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Recurrent Pregnancy Loss, Anxiety
Cardiac Autonomic and Anxiety Regulation Via Closed-loop nEurofeedback in Recurrent Pregnancy Loss
The goal of this clinical trial is to learn whether right dorsolateral prefrontal cortex (right DLPFC)-targeted fNIRS-BCI online closed-loop neurofeedback, delivered with slow-wave acoustic cueing, can reduce anxiety symptoms and…
- Trial name
- CARE-RPL (NCT07325370)
- Testing
- Right DLPFC fNIRS-BCI closed-loop neurofeedback (real feedback)
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Shenyang Medical College
Abortion, Habitual, Nutritional Status
Nutritional Deficiencies About Recurrent Miscarriage
The study plans to recruit patients with recurrent miscarriage and detect their niacin, thiamine, vitamin A, vitamin B6, vitamin B12, vitamin D levels in plasma, evaluating if some lack exists.
- Trial name
- NCT04064931
- Testing
- Detection of niacin and other vitamins in plasma
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital