Clinical trials: Recurrent Urinary Tract Infection
Urinary Tract Infections, Recurrent
Antibiotic Prophylaxis for Clean Intermittent Catheterisation
This research project is designed to find out whether people who suffer repeated urinary tract infections (UTI) related to the need to empty their bladders intermittently with a fine plastic tube (catheter); a process called…
- Trial name
- AnTIC (NCT02145338)
- Testing
- Nitrofurantoin or Trimethoprim or Cefalexin, No prophylaxis
- Where
- United Kingdom
- Volunteers
- 404 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Periodontitis, Chronic Prostatitis (CP)
Periodontal Therapy and Genitourinary Inflammation in Patients With Prostatitis and Recurrent Urinary Tract Infections
This randomized controlled clinical trial evaluates the impact of non-surgical periodontal therapy on systemic inflammatory markers in patients with chronic prostatitis or recurrent urinary tract infections.
- Conditions
- Periodontitis, Chronic Prostatitis (CP), Urinary Tract Infections
- Trial name
- PERIO-PSA (NCT07438184)
- Testing
- Non-surgical periodontal therapy, Oral hygiene instruction
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Salamanca
Bladder Cancer, Brain and Central Nervous System Tumors
High-dose ICE With Amifostine
The purpose of the study is to evaluate the combination of amifostine and high dose chemotherapy with blood stem cell support. Amifostine is a druf developed to protect normal tissues against the toxicities of chemotherapy and…
- Conditions
- Bladder Cancer, Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Extragonadal Germ Cell Tumor
- Trial name
- NCT00003657
- Testing
- filgrastim, Amifostine, Carboplatin
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Dana-Farber Cancer Institute
Urinary Tract Infections, Vaginal Flora Imbalance
Vaginal Care System for Menopausal Women With Urinary Tract Infections
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause.
- Trial name
- NCT05573334
- Testing
- BioNourish
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vaginal Biome Science
Recurrent Urinary Tract Infections
Retrospective Analysis of Ialuril vs. Standard of Care in Recurrent Urinary Tract Infections
The purpose of this study is to assess the effectiveness and costs associated with the intravesical administration of combined hyaluronic acid (HA) and chondroitin sulphate (CS) compared to the current standard management of…
- Trial name
- RAISC-RUTI (NCT02016118)
- Testing
- Ialuril
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Study Group for Urogenital Diseases, Italy
Urinary Tract Infections, Recurrent
Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIs
Several methods are available for use in the prevention of recurrent urinary tract infections (UTIs) over the past few decades. These methods include suppressive antibiotics, estrogen cream, methenamine hippurate, d-mannose…
- Trial name
- NCT03077711
- Testing
- Trimethoprim, Methenamine hippurate
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Recurrent Urinary Tract Infections in Women
Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women
The goal of this clinical trial is to learn if drug U101 works to prevent recurrent urinary tract infection (rUTI) in women (≥ 20 and < 76 years old) with a medical history.
- Trial name
- U101 (NCT07184827)
- Testing
- U101
- Where
- 18 sites in Taiwan
- Volunteers
- 348 people
- Sponsor
- TCM Biotech International Corp.
Recurrent Urinary Tract Infection
GAG Replacement vs URethral DIlAtatioN
The aim of this randomised parallel trial is to compare the efficacy of Glycosaminoglycan layer replacement against cystoscopy and urethral dilatation in the treatment of recurrent urinary tract infection in pre-menopausal women.
- Trial name
- GUARDIAN (NCT03861260)
- Testing
- Rigid cystoscopy with urethral dilatation, Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
- Where
- United Kingdom
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Urinary Tract Infections (UTIs)
Evaluation of the Effectiveness and Safety of a Vaginal Gel for Prevention of Recurrent Urinary Tract Infections
Urinary Tract Infections (UTIs) are among the most common bacterial infections. Although they are typically treated effectively with antibiotics, recurrence is a frequent and troublesome issue.
- Trial name
- UTI (NCT07233473)
- Testing
- Multi-Gyn UT Protect gel
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Urinary Tract Infections, Patients With Suprabubic Catheter
Study of E. Coli Isolates From Recurrent Urinary Tract Infections
Prospective study aiming at collecting clinical Escherichia coli isolates from patients with recurrent urinary tract infection; samples to be collected during routine procedures.
- Conditions
- Urinary Tract Infections, Patients With Suprabubic Catheter, Patients With Nephrostomy Catheter
- Trial name
- Per-UTI (NCT05826067)
- Testing
- collection of bacterial strains
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Université Catholique de Louvain
Urinary Tract Infection, Recurrent
Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients
This proposal will take an important first step in the study of phage therapy for treatment of recurrent urinary tract infection (rUTI) in female kidney transplant recipients (KTR); a common condition that is associated with…
- Trial name
- NCT06409819
- Testing
- phage therapy, control
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Diego
Interstitial Cystitis, Chronic, Overactive Bladder Syndrome
Real-life Clinical Experience With Ialuadapter Study
A retrospective study from a single center was performed. Quantitative and qualitative data was obtained on the use of the syringe adapter (IALUADAPTER®) in 61 patients with IC/BPS (n=48), rUTI (n=6) and mixed /other diagnoses…
- Conditions
- Interstitial Cystitis, Chronic, Overactive Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- Ialuadapter (NCT06540248)
- Testing
- Ialuadapter
- Where
- Netherlands
- Volunteers
- 61 people
- Sponsor
- Radboud University Medical Center
Uncomplicated Symptomatic Urinary Tract Infections
Assess the Effects of a Limosilactobacillus Supplement on Recurrence of UTI in Healthy Women During a 6-month Period
The goal of this clinical trial is to assess the efficacy of the probiotic Limosilactobacillus reuteri 3613 for the decrease or prevent UTI occurrence in women ages 18-65 with a confirmed medical history of recurrent…
- Trial name
- NCT05793814
- Testing
- Limosilactobacillus reuteri 3613
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Church & Dwight Company, Inc.
Urinary Tract Infections
Uqora Supplements in Women With UTIs
This is a virtual study which will invite females over the age of 18 who have had 2 or more UTIs in the past 6 months to participate.
- Trial name
- NCT04024046
- Testing
- Uqora, Group1, Group 2
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hawthorne Effect Inc.
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Bladder Cancer, Breast Cancer
Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or…
- Conditions
- Bladder Cancer, Breast Cancer, Carcinoma of Unknown Primary, Esophageal Cancer
- Trial name
- NCT00014456
- Testing
- filgrastim, docetaxel, gemcitabine hydrochloride
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Recurrent Urinary Tract Infections
Recurrent Urinary Tract Infections and Heparin (RUTIH Trial)
Urinary Tract Infections (UTIs) are the second most common infection in the body. UTIs account for five percent of all visits to primary care physicians.
- Trial name
- NCT02246270
- Testing
- Intravesical Heparin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Recurrent Urinary Tract Infection, Vaginal Atrophy
Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo
Women over the age of 60 years have an estimated 10 to 15 % risk of recurrent urinary tract infections (UTI). This is believed to be due to hormonally induced changes in the vaginal flora associated with menopause.
- Conditions
- Recurrent Urinary Tract Infection, Vaginal Atrophy, Postmenopausal Disorder
- Trial name
- PIVoT (NCT04807894)
- Testing
- Vaginal Cream with Applicator
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Jefferson Drapkin
Urinary Tract Infection
High Strength Cranberry Supplementation for Prevention of Recurrent Urinary Tract Infection
This clinical trial is a Phase 2, multicenter, placebo-controlled, double-blind, parallel-arm study to evaluate the efficacy and safety of High Strength Cranberry (500mg Pacran®) in preventing UTI (cystitis) in women with a…
- Trial name
- NCT03042273
- Testing
- High Strength Cranberry
- Where
- 5 sites in Australia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Swisse Wellness Pty Ltd
Recurrent Urinary Tract Infection
Recurrent Urinary Tract Infections and the Microbiome
The primary objective is to determine if polymerase chain reaction (PCR) (UTIP™) is more sensitive in identifying urinary tract infections (UTI's) than standard urine cultures.
- Trial name
- NCT04831840
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Miami