Clinical trials: Recurrent Uti
Neurogenic Bladder, Urinary Retention
Effect of Chlorhexidine Gluconate Bladder Instillations in Patients With Chronic Suprapubic Catheters on Unplanned Healthcare Encounters and Quality of Life
The goal of this clinical trial is to evaluate the feasibility and tolerability of 0.05% Chlorhexidine Gluconate (CGH) bladder instillations in an outpatient setting at the time of suprapubic catheter (SPC) exchange in patients…
- Trial name
- NCT06163469
- Testing
- Bladder instillation with Irrisept
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Yale University
Recurrent Urinary Tract Infection, Hypoestrogenism
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn about medication adherence to difference types of vaginal estrogen in women with low levels of estrogen (for example, post-menopausal women) who have recurrent urinary tract infections.
- Trial name
- NCT06353269
- Testing
- Estring Vaginal Product, Vagifem, Estrace 0.01% Vaginal Cream
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Infection Due to ESBL Escherichia Coli
Fosfomycin Versus Meropenem or Ceftriaxone in Bacteriemic Infections Caused by Multidrug Resistance in E.Coli
Enterobacterieaceae (and specially Escherichia coli) showing resistance due to multidrug-resistant Escherichia coli, plasmid mediated AmpC or quinolone resistance caused by chromosomal mechanisms have spread worldwide during the…
- Trial name
- FOREST (NCT02142751)
- Testing
- Fosfomycin sodium intravenous, Meropenem intravenous, Ceftriaxone intravenous
- Where
- 22 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Urinary Tract Infections (UTIs), Urinary Tract Infection, Recurrent
Effects of Pomegranate Seed Oil Supplementation in Patients With Advanced Dementia
The goal of this clinical study is to learn if Pomegranate Seed Oil supplementation works to combat urinary tract infections, recurrenturinary tract infections, or pneumonia and contributes to the tapering or discontinuation of…
- Conditions
- Urinary Tract Infections (UTIs), Urinary Tract Infection, Recurrent, Antipsychotics Discontinuation, Antipsychotics Tapering
- Trial name
- NCT07432763
- Testing
- Pomegranate Seed Oil Supplementation in Palliative Care Patients with Advanced Dementia, Care-as-usual
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Panhellenic Federation of Alzheimer's Disease and Related Disorders
Interstitial Cystitis, Chronic, Overactive Bladder Syndrome
Real-life Clinical Experience With Ialuadapter Study
A retrospective study from a single center was performed. Quantitative and qualitative data was obtained on the use of the syringe adapter (IALUADAPTER®) in 61 patients with IC/BPS (n=48), rUTI (n=6) and mixed /other diagnoses…
- Conditions
- Interstitial Cystitis, Chronic, Overactive Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- Ialuadapter (NCT06540248)
- Testing
- Ialuadapter
- Where
- Netherlands
- Volunteers
- 61 people
- Sponsor
- Radboud University Medical Center
Recurrent UTIs, Cystitis Recurrent
Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn if the drug Nitrofurantoin (NF) taken as a daily antibiotic, works to treat cystitis compared to electrofulguration (EF) and Nitrofurantoin (NF) daily antibiotic.
- Trial name
- NCT06907199
- Testing
- Electrofulguration (EF), Nitrofurantoin (NF)
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Texas Southwestern Medical Center
Recurrent Urinary Tract Infection
Phage Therapy for the Treatment of Urinary Tract Infection
This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of bacteriophage therapy to treat and prevent the recurrence of a drug-resistant urinary tract infection with serious long-term effects.
- Trial name
- NCT05537519
- Testing
- Phage Therapy
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Unity Health Toronto
Urinary Tract Infections
Efficacy and Mechanism of Action of Methenamine Hippurate (Hiprex™) in Women With Recurring Urinary Tract Infections.
The purpose of this study is to measure the concentration of formaldehyde in the urine of women with recurrent urinary tract infections on Hiprex; and then, assuming its urinary presence is confirmed at the proper acid urinary…
- Trial name
- NCT04709601
- Testing
- Hiprex
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Interstitial Cystitis, Painful Bladder Syndrome
Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder
Pilot study to determine feasibility for treating patients with two chronic inflammatory conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract infections using a standardized hyperbaric…
- Conditions
- Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- HBOTCICrUTI (NCT03143920)
- Testing
- Hyperbaric Oxygen Therapy-
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Diego
Urinary Tract Infections, Recurrent Urinary Tract Infections
WMT for Multidrug-Resistant Organism UTI
This is a single-center, prospective, single-arm, exploratory clinical study to evaluate the efficacy, safety, and potential mechanisms of washed microbiota transplantation (WMT) in patients with recurrent urinary tract…
- Conditions
- Urinary Tract Infections, Recurrent Urinary Tract Infections, Multidrug-Resistant Bacterial Infections, Bacteriuria
- Trial name
- NCT07816913
- Testing
- Washed Microbiota Transplantation (WMT)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Recurrent Urinary Tract Infection
The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing in Elderly Women With Recurrent UTI
Recurrent urinary tract infection (UTI) in elderly women is a major driver of antibiotic prescription. Hence, the question of feasible and appropriate preventive measures are important issues in this field.
- Trial name
- ImpresUWP3 (NCT04077580)
- Testing
- Methenamine Hippurate 1000 MG
- Where
- 4 sites in Netherlands, Norway and 2 more
- Volunteers
- 289 people
- Sponsor
- University of Oslo
Urinary Tract Infections
Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis
This is a double-blind, randomized, double-dummy, comparative study in parallel groups of subjects presenting with recurrent cystitis (≥2 episodes within the past 6 months).
- Trial name
- NCT03379389
- Testing
- Methenamine + Methylthioninium, Methenamine + Methylthioninium + Acriflavine + Atropa belladona, Antibiotics
- Where
- Brazil
- Volunteers
- 284 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Recurrent Urinary Tract Infection in Adult Women
Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection in Adult Women
Urinary tract infections (UTIs) are the most common bacterial infections in women, with about 50% of women experiencing at least one UTI in their lifetime.
- Trial name
- NCT03366077
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Urinary Tract Infection(UTI), Recurrent Urinary Tract Infections
Emotional Urinary Tract Infection
This project proposes a rigorous investigation into the psychological impact of positive urine culture results and recurrent urinary tract infections (UTIs) in women, with a particular focus on Interstitial Cystitis and Bladder…
- Trial name
- UTI (NCT07191041)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Northwell Health
Urinary Tract Infections
Diagnosis, Antibiotic Prescribing Practices and Outcomes of cUTI in an Outpatient Setting
This prospective, multicenter, comparative cohort observational study is to determine if Guidance® UTI pathway compared to traditional diagnostic pathways reduces the rates of empiric antibiotic therapy, adverse events, and…
- Trial name
- NCT05091931
- Where
- 2 sites in United States
- Volunteers
- 3,308 people
- Sponsor
- Pathnostics
Urinary Tract Infections
Evaluation of the Prevalence of E. Coli O Serotypes in Paediatric Population With Recurrent Urinary Tract Infection
This is a multicentre, observational, epidemiological study in which infants within the first 3 months of life with UTI and children aged ≥4 months with r-UTI will be recruited from nephrology /emergency departments and primary…
- Trial name
- rUTI (NCT06482151)
- Sponsor
- PENTA Foundation
Recurrent Urinary Tract Infections
Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis)
This randomized, double-blind, placebo-controlled trial will evaluate the efficacy of a probiotic food supplement containing Lactiplantibacillus plantarum PBS067, Lacticaseibacillus rhamnosus LRH020, and Bifidobacterium animalis…
- Trial name
- BIO-RUTI-26 (NCT07884929)
- Testing
- Dietary Supplement containing probiotics
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Synbalance S.r.l.
UTI's
An Efficacy Study of a Dietary Supplement Drink Mix for Urinary Health Improvement
This is a 6-month, three-arm randomized controlled trial evaluating the efficacy and safety of a dietary supplement drink mix on urinary health outcomes in adult females.
- Trial name
- NCT07453693
- Testing
- FLUSH
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Urinary Tract Infections, Urinary Tract Infection (UTI)
Alternative Prophylaxis in Female Recurrent Urinary Tract Infections
Urological pathogens are effected by rising antimicrobial resistance rates due to the frequent use of antimicrobials for treatment and prophylaxis.
- Trial name
- AlP-FrUiT (NCT04095572)
- Testing
- intravesical instillation with HA-CS, intravesical instillation of sterile purified water
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Basel, Switzerland
Recurrent Urinary Tract Infection
Gag Therapy for Recurrent Urinary Tract Infection Assessing Comparability to International Nitrofurantoin Gold Standard Study
The GT RACING is a study comparing the efficacy of HA-CS bladder installations with prophylactic antibiotics in the prevention of recurrent urinary tract infections (rUTI).
- Trial name
- GT RACING (NCT05652374)
- Testing
- Ialuril 50ml Prefill, Nitrofurantoin
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center