Clinical trials: Redness
Metabolic Syndrome
Korean Red Ginseng and Metabolic Syndrome
Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until now, several studies have been performed about effects of Korea red ginseng on hypertension, diabetes, and hyperlipidemia, but not…
- Trial name
- NCT00976274
- Testing
- Korean red ginseng, starch
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- The Korean Society of Ginseng
Myopia, Refractive Errors
Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure
The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.
- Conditions
- Myopia, Refractive Errors, Eye Diseases, Retina; Change
- Trial name
- NCT05597397
- Testing
- RLRL
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Sickle Cell Disease
Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE)
The SCD-CARRE trial is a Phase 3, prospective, randomized, multicenter, controlled, parallel two-arm study aimed to determine if automated exchange blood transfusion and standard of care administered to high mortality risk adult…
- Trial name
- SCD-CARRE (NCT04084080)
- Testing
- Red Blood Cell, Standard of care
- Where
- 23 sites in United States, Brazil and 1 more
- Volunteers
- 173 people
- Sponsor
- University of Pittsburgh
Linperlisib, PRCA
Low-Dose Linperlisib Achieves Rapid Hematological Response in a Patient With Pure Red Cell Aplasia and Moderate-to-Severe Renal Insufficiency: A Case Report
This article reports a case of a 70-year-old male patient diagnosed with T-cell large granular lymphocytic leukemia (T-LGLL)-associated pure red cell aplasia (PRCA) complicated by moderate-to-severe renal insufficiency.
- Conditions
- Linperlisib, PRCA, Moderate-to-Severe Renal Insufficiency
- Trial name
- NCT07900282
- Testing
- linperlisib
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Peking Union Medical College Hospital
Ocular Redness
"Efficacy and Safety of Brimonidine Tartrate Preservative-Free Formulation in Adults With Ocular Redness"
This is a multi-center, double-masked, randomized, active-controlled, parallel-group, efficacy and safety study that will enroll 386 participants at up to six clinical sites.
- Trial name
- NCT05360784
- Testing
- Brimonidine tartrate ophthalmic solution 0.025% preservative-free formulation, Lumify® (brimonidine tartrate ophthalmic solution 0.025%)
- Where
- 6 sites in United States
- Volunteers
- 380 people
- Sponsor
- Bausch & Lomb Incorporated
Thalassemia
A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia
This is a Phase 2, double-blind, randomized, placebo-controlled, multicenter study to determine the efficacy and safety of luspatercept (ACE-536) versus placebo in adults with non-transfusion dependent beta (β)-thalassemia.
- Trial name
- BEYOND (NCT03342404)
- Testing
- Luspatercept, Best Supportive Care (BSC)
- Where
- 16 sites in United States, Greece and 4 more
- Volunteers
- 145 people
- Sponsor
- Celgene
Stevens-Johnson Syndrome
Stevens-Johnson Syndrome Antimicrobial
Steven-Johnson's syndrome, or great multiform erythema, appears as a systemic disturbance, with skin involvement and mucous membranes, related to several factors, such as, viral or bacterial infections and mainly the…
- Trial name
- NCT00844038
- Where
- Brazil
- Volunteers
- 1 people
- Sponsor
- University of Pernambuco
Breast Cancer
Red Clover and Lifestyle Changes to Contrast Menopausal Symptoms in Premenopausal Breast Cancer Patients Given Tamoxifen
A prospective double-blind randomized trial of red clover extract (Promensil) vs placebo in surgically-treated premenopausal women with estrogen receptor-positive breast cancer taking tamoxifen
- Trial name
- NCT03844685
- Testing
- Promensil
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Erythema Nodosum Leprosum
A Study to Evaluate the Efficacy and Safety of Apremilast in Patients of Chronic and Recurrent Erythema Nodosum Leprosum
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The disease manifests with a varied spectrum, ranging from localized tuberculoid leprosy (TT) to generalized lepromatous leprosy (LL) types.
- Trial name
- NCT04822909
- Testing
- Apremilast;Apremilast;Apremilast 10 MG; 20 MG; 30 MG Oral Tablet
- Where
- 3 sites in India
- Volunteers
- 10 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Healthy
Effect of Red Meat Intake on Occurrence of Serum Non-transferrin Bound Iron (NTBI)
This study aims to evaluate the effect of red meat intake on occurrence of non-transferrin bound iron (NTBI)
- Trial name
- NCT03019393
- Testing
- Beef
- Where
- Singapore
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Thomas Walczyk
Drug Absorption
Effect of Gamma-cyclodextrin on the Bioavailability of Ginsenosides
This study will evaluate the relative bioavailability of ginsenosides Rg5, Rk1, and Ck of Red ginseng HRG80 preparations containing gamma-cyclodextrin (GCD) in the blood plasma of healthy subjects after oral administration of two…
- Trial name
- NCT04932265
- Testing
- HRG80™ Red Ginseng, HRG80™ Red Ginseng + gamma cyclodextrin
- Where
- 4 sites in Armenia, Sweden
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- EuroPharma, Inc.
Toxic Epidermal Necrolysis
Topical Clobetasol for the Treatment of Toxic Epidermal Necrolysis
The primary objectives of this study are to investigate the efficacy and safety of topical steroid ointment (clobetasol 0.05%) for the treatment of the cutaneous manifestations of toxic epidermal necrolysis (TEN).
- Trial name
- TEN (NCT02319616)
- Testing
- Clobetasol 0.05% ointment
- Where
- United States
- Sponsor
- University of California, Davis
Type 2 Diabetes
Effects of Red Grape Cells (RGC) Powder in Type 2 Diabetics
The aim of this study is to examine whether the chronic administration during 12 weeks of polyphenols contained in Red Grape Cells (RGC) powder has an effect on mRNA expression of SIRT1 and Clock Genes, on circulating levels of…
- Trial name
- RGC-T2D (NCT01938521)
- Testing
- Red Grape Cells (RGC)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Retinopathy of Prematurity (ROP), Bronchopulmonary Dysplasia (BPD)
The Correlation Between Red Cell Transfusion and Complications of Prematurity
The aim of this clinical trial is to learn if there is a correlation between the erythrocyte transfusion in the early neonatal period in premature infants and early and late complications of prematurity.
- Conditions
- Retinopathy of Prematurity (ROP), Bronchopulmonary Dysplasia (BPD), Enterocolitis, Necrotizing, Intraventricular Hemorrhage Neonatal
- Trial name
- NCT07123948
- Testing
- Wechsler Intelligence Test, performed by educated psychologists
- Where
- Croatia
- Volunteers
- 128 people
- Sponsor
- Clinical Hospital Center Rijeka
Type 2 Diabetes
Relationship Between Red Cell Distribution Width (RDW) and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic Control
Diabetes mellitus (DM) is an epidemic disease, with approximately 463 million persons diagnosed with it. Of those, 90% are patients with type 2 DM (T2DM).
- Trial name
- NCT06067399
- Testing
- Glycated hemoglobin (HbA1C), RDW, Lipid profile
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- New Valley University
Platelet Aggregation, Blood Transfusion
Validation of a Red Blood Cell Transfusion Prediction Model in a Low Transfusion Rate Population.
The transfusion risk and clinical knowledge (TRACK) allogeneic blood transfusion prediction model was developed more than ten years ago and demonstrated good discriminative ability in patients with increased risk for allogeneic…
- Trial name
- TRACK-TCT (NCT05581238)
- Testing
- TRACK-TCT
- Where
- Netherlands
- Volunteers
- 6,428 people, healthy volunteers welcome
- Sponsor
- Medisch Spectrum Twente
Acute Normovolemic Hemodilution
Acute Normovolemic Hemodilution in Bone Cancer Surgery
Malignant bone tumors often lead to skeletal complications, known as skeletal related events (SRE). These complications mainly include pathological fractures, severe pain, and spinal cord compression.
- Trial name
- NCT07669155
- Testing
- Acute Normovolemic Hemodilution
- Where
- 8 sites in China
- Volunteers
- 420 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vision
Does the VTS1000 Infra Red Vein Imager Allow Better Identification of Veins Than Normal Eyesight?
VueTek has developed a head mounted device that will improve the viewing of superficial, subcutaneous vasculature, differentiating it with higher contrast from surrounding tissue.
- Trial name
- VFvalidation (NCT01138228)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
RBC Transfusions
Clinical Impact of Red Cell Storage Age
The recent four RCTs evaluating effects of RBC storage age on morbidity and mortality found no statistically significant adverse effects of longer stored RBC compared to shorter storage ages.
- Trial name
- NCT05482737
- Testing
- no intervention
- Where
- United States
- Volunteers
- 33,000 people
- Sponsor
- University of Minnesota
Sickle Cell Disease, Sickle Cell Anemia
Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease
Background: Sickle cell disease (SCD) is an inherited blood disorder. It results from a single genetic change (mutation) in red blood cells (RBCs). RBCs are the cells that carry oxygen to the body.
- Trial name
- NCT04476277
- Testing
- Biotin label
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)