Clinical trials: Reduction in Pain, open to volunteers
Phantom Limb Pain, Amputation
TITAN Trial: Reducing Phantom Limb Pain in People with Amputations
The goal of this clinical trial is to investigate the effectiveness of two rehabilitation programs for individuals who have undergone amputations and are experiencing phantom limb pain.
- Trial name
- TITAN (NCT06167330)
- Testing
- Progressive rehabilitation program, Stimulation devices
- Where
- Australia
- Volunteers
- 208 people
- Sponsor
- Neuroscience Research Australia
Dental Anxiety in Children, Dental Pain
Kaleidoscope Compared to Tell-Show-Do for Reducing Children Pain and Anxiety During Pulp Therapy
The goal of this clinical trial is to investigate if Kaleidoscope glasses help children feel less pain and worry during dental work. It will also explore if these glasses help children feel more comfortable with the dentist.
- Trial name
- NCT07595731
- Testing
- behavior management using Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique and Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique.
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Supracondylar Humerus Fracture
Supracondylar Post-Operative Pain Study
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning.
- Trial name
- NCT03759028
- Testing
- Ibuprofen, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Chronic Respiratory Diseases
Interest of Cryotherapy in Reducing Pain During Radial Arterial Blood Sampling
Arterial puncture for blood gas analysis is a diagnostic procedure used to assess arterial blood gases and monitor a patient's oxygenation status.
- Trial name
- HOURRA (NCT07408011)
- Testing
- Apllication of medical device ice pack, Apllication of cream
- Where
- 2 sites in France
- Volunteers
- 258 people
- Sponsor
- University Hospital, Brest
Pain
Effect of Music in Reducing Pain and Anxiety During Hysterosalpingography in Women With Primary Infertility
This study aims to demonstrate the value of music in lowering pain and anxiety during hysterosalpingography in women with primary infertility
- Trial name
- NCT06772636
- Testing
- music group, non music group
- Volunteers
- 110 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome (CTS)
Evaluation of Dynavisc in Pain Reduction Following Revision Surgery for Persistent or Recurrent Carpal Tunnel Syndrome
The trial will evaluate the efficacy of DYNAVISC in subjects with a diagnosis of persistent or recurrent carpal tunnel syndrome. This is a prospective, multicenter, randomized, evaluator-blinded clinical trial.
- Trial name
- NCT06593977
- Testing
- Dynavisc
- Where
- 4 sites in Belgium, Brazil and 1 more
- Volunteers
- 50 people
- Sponsor
- FzioMed
Lung Cancer Patients
Press Needle Acupuncture for Pain and Quality of Life in Lung Cancer Patients
The purpose of this clinical trial is to evaluate the effect of press needle acupuncture on pain management and quality of life improvement in patients with lung cancer.
- Trial name
- NCT07112950
- Testing
- Press Needle Acupuncture and standart therapy
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Pulpotomies Primary Teeth, Anxiety
Dental Game Impact on Kids' Pulpotomy Pain and Anxiety
The aim of this study is to evaluate the effect of a dental simulation game on reducing pain and anxiety during primary teeth pulpotomy.
- Conditions
- Pulpotomies Primary Teeth, Anxiety, Pain
- Trial name
- Electronic (NCT07072559)
- Testing
- dental simulation game, tell show do
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Infertility, Female
Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility
We aim to assess the Safety and Efficacy of Cervical Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in women with primary infertility
- Trial name
- NCT06769204
- Testing
- EMLA SPRAY
- Volunteers
- 90 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis
This study will test whether inulin, a type of dietary fiber, can reduce inflammation in older adults with knee osteoarthritis. Inflammation in the body may contribute to both joint pain and the progression of osteoarthritis.
- Trial name
- OA-INULIN (NCT07189585)
- Testing
- inulin
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Yale University
Sickle Cell Disease, Vaso-occlusive Pain Episodes
Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain
The goal of this randomized control clinical trial is to learn if virtual reality can be used to treat sickle cell pain in children.
- Trial name
- NCT06773715
- Testing
- KindVR Aqua Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Apical Periodontitis, Necrotic Pulps
A Comparative Evaluation of the Degree of Pain and MMP-9 Expression Following Instrumentation of Necrotic Pulps With Apical Periodontitis in One or Two Visits
This randomized clinical trial compares postoperative pain and MMP-9 levels after root canal treatment of necrotic teeth with apical periodontitis, using either single-visit or two-visit instrumentation.
- Conditions
- Apical Periodontitis, Necrotic Pulps, Single Rooted Teeth
- Trial name
- NCT07101003
- Testing
- single visit instrumentation, multiple visit instrumentation
- Volunteers
- 28 people
- Sponsor
- Marwa Hisham Mohamed Salah Eldin
Chronic Pain, Widespread, Obesity
Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults
The goal of this observational study is to learn if surgical weight loss can improve chronic widespread pain in people living with higher BMI who self-identify as Hispanic/Latino ethnicity or non-Hispanic Black based on the…
- Conditions
- Chronic Pain, Widespread, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT06795386
- Testing
- Bariatric Surgery
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- New York University
Preventing Propofol Pain on Injection
Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain
Propofol is the most popular IV anaesthetic agent used for induction, however one of its known side effects is causing pain on injection, the gold standard method in preventing this pain is using lidocaine prior to injecting…
- Trial name
- NCT07116304
- Testing
- Lidocaine, a local anaesthetic., Parecoxib 40mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Back Pain
Health Effects of Mindfulness Based Stress Reduction Course in Treatment of Back Pain
Health effects of mindfulness based stress reduction course versus usual care in treatment of back pain: a randomized clinical trial Mindfulness based stress reduction (MBSR) course intervention for half of the research patients…
- Trial name
- NCT07528833
- Testing
- Mindfulness based stress reduction (MBSR) course
- Where
- 4 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Tampere University Hospital
Chronic Pain, Chronic Insomnia
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT06345872
- Testing
- CBT-I, Treatment as usual, Tapered Withdrawal
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Colectomy, Open Surgery
Perioperative Intravenous Nimodipine Trial
The role of perioperative IV administration of nimodipine, an L-type calcium channel antagonist which is capable of crossing the blood-brain barrier, on peri-operative opioid and anesthetics requirements, pain intensity…
- Conditions
- Colectomy, Open Surgery, Pain, Pain, Postoperative
- Trial name
- NCT07048522
- Testing
- Nimodipine, Isotonic Saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Ioannina
Orthopedic Trauma Surgery Patients, Postoperative Pain
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma.
- Conditions
- Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression
- Trial name
- NCT06903819
- Testing
- Ketamine, standard general anesthesia
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Texas Tech University Health Sciences Center
Breast Cancer Females
Auricular Acupressure for Perioperative Anxiety and Pain in Therapeutic Breast Surgery (ROSA)
This randomized, controlled, single-center trial investigates the effects of auricular acupressure, administered according to the National Acupuncture Detoxification Association (NADA) protocol, on perioperative anxiety and pain…
- Trial name
- ROSA (NCT07423039)
- Testing
- Auricular Acupressure NADA
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Post Operative Pain in Total Abdominal Hystrectomy
Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy
The goal of this study is to know how effectively TAP block can reduce postoperative pain in total abdominal hystrectomy patients when given ketamine in addition to bupivacaine in TAP block and to compare it with the conventional…
- Trial name
- TAP-BvsBK-TAH (NCT07482709)
- Testing
- bupivicaine 0.25%, bupivicaine 0.25% + ketamine
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Liaquat National Hospital & Medical College