Clinical trials: Reduction in Pain, active
Phantom Limb Pain, Amputation
TITAN Trial: Reducing Phantom Limb Pain in People with Amputations
The goal of this clinical trial is to investigate the effectiveness of two rehabilitation programs for individuals who have undergone amputations and are experiencing phantom limb pain.
- Trial name
- TITAN (NCT06167330)
- Testing
- Progressive rehabilitation program, Stimulation devices
- Where
- Australia
- Volunteers
- 208 people
- Sponsor
- Neuroscience Research Australia
Dental Anxiety in Children, Dental Pain
Kaleidoscope Compared to Tell-Show-Do for Reducing Children Pain and Anxiety During Pulp Therapy
The goal of this clinical trial is to investigate if Kaleidoscope glasses help children feel less pain and worry during dental work. It will also explore if these glasses help children feel more comfortable with the dentist.
- Trial name
- NCT07595731
- Testing
- behavior management using Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique and Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique.
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Analgesia in Breast Reduction Surgery, Postoperative Pain
Comparison of Serratus Plane Block and Rhomboid Intercostal Plane Block for Postoperative Analgesia in Breast Reduction Surgery
This prospective, randomized clinical study aims to compare the analgesic efficacy of serratus plane block (SPB) and rhomboid intercostal plane block (RIPB) for postoperative analgesia in patients undergoing elective bilateral…
- Conditions
- Postoperative Analgesia in Breast Reduction Surgery, Postoperative Pain, Postoperative Pain Breast Reduction, Pain, Postoperative
- Trial name
- SAPB-RIPB (NCT07229092)
- Testing
- Serratus Anterior Plane Block (SAPB), Rhomboid Intercostal Plane Block (RIPB), No Regional Block (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konul Karaja
Supracondylar Humerus Fracture
Supracondylar Post-Operative Pain Study
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning.
- Trial name
- NCT03759028
- Testing
- Ibuprofen, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Chronic Respiratory Diseases
Interest of Cryotherapy in Reducing Pain During Radial Arterial Blood Sampling
Arterial puncture for blood gas analysis is a diagnostic procedure used to assess arterial blood gases and monitor a patient's oxygenation status.
- Trial name
- HOURRA (NCT07408011)
- Testing
- Apllication of medical device ice pack, Apllication of cream
- Where
- 2 sites in France
- Volunteers
- 258 people
- Sponsor
- University Hospital, Brest
Pain
Effect of Music in Reducing Pain and Anxiety During Hysterosalpingography in Women With Primary Infertility
This study aims to demonstrate the value of music in lowering pain and anxiety during hysterosalpingography in women with primary infertility
- Trial name
- NCT06772636
- Testing
- music group, non music group
- Volunteers
- 110 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome (CTS)
Evaluation of Dynavisc in Pain Reduction Following Revision Surgery for Persistent or Recurrent Carpal Tunnel Syndrome
The trial will evaluate the efficacy of DYNAVISC in subjects with a diagnosis of persistent or recurrent carpal tunnel syndrome. This is a prospective, multicenter, randomized, evaluator-blinded clinical trial.
- Trial name
- NCT06593977
- Testing
- Dynavisc
- Where
- 4 sites in Belgium, Brazil and 1 more
- Volunteers
- 50 people
- Sponsor
- FzioMed
Lung Cancer Patients
Press Needle Acupuncture for Pain and Quality of Life in Lung Cancer Patients
The purpose of this clinical trial is to evaluate the effect of press needle acupuncture on pain management and quality of life improvement in patients with lung cancer.
- Trial name
- NCT07112950
- Testing
- Press Needle Acupuncture and standart therapy
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Pulpotomies Primary Teeth, Anxiety
Dental Game Impact on Kids' Pulpotomy Pain and Anxiety
The aim of this study is to evaluate the effect of a dental simulation game on reducing pain and anxiety during primary teeth pulpotomy.
- Conditions
- Pulpotomies Primary Teeth, Anxiety, Pain
- Trial name
- Electronic (NCT07072559)
- Testing
- dental simulation game, tell show do
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Infertility, Female
Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility
We aim to assess the Safety and Efficacy of Cervical Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in women with primary infertility
- Trial name
- NCT06769204
- Testing
- EMLA SPRAY
- Volunteers
- 90 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis
This study will test whether inulin, a type of dietary fiber, can reduce inflammation in older adults with knee osteoarthritis. Inflammation in the body may contribute to both joint pain and the progression of osteoarthritis.
- Trial name
- OA-INULIN (NCT07189585)
- Testing
- inulin
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Yale University
Sickle Cell Disease, Vaso-occlusive Pain Episodes
Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain
The goal of this randomized control clinical trial is to learn if virtual reality can be used to treat sickle cell pain in children.
- Trial name
- NCT06773715
- Testing
- KindVR Aqua Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Symptomatic Irreversible Pulpitis (SIP)
Measure Postoperative Pain and Bacterial Reduction After Different Final Irrigation Protocols.
The primary objective of root canal treatment is to clean, disinfect, and hermetically seal the root canal system to prevent bacterial penetration; however, postoperative pain is frequently encountered, particularly in patients…
- Trial name
- PIRRI (NCT07191990)
- Testing
- Final irrigation by cryotreated NaOcl., Final irrigation by preheated NaOcl, Final irrigation with ultrasonic activation of NaOcl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Liver and Intrahepatic Bile Duct Disorder
Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery
This phase III trial studies how well thoracic epidural analgesia or four-quadrant transversus abdominus plane block works in reducing pain in patients undergoing liver surgery.
- Trial name
- NCT03214510
- Testing
- Bupivacaine, Fentanyl, Hydromorphone Hydrochloride
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- M.D. Anderson Cancer Center
Apical Periodontitis, Necrotic Pulps
A Comparative Evaluation of the Degree of Pain and MMP-9 Expression Following Instrumentation of Necrotic Pulps With Apical Periodontitis in One or Two Visits
This randomized clinical trial compares postoperative pain and MMP-9 levels after root canal treatment of necrotic teeth with apical periodontitis, using either single-visit or two-visit instrumentation.
- Conditions
- Apical Periodontitis, Necrotic Pulps, Single Rooted Teeth
- Trial name
- NCT07101003
- Testing
- single visit instrumentation, multiple visit instrumentation
- Volunteers
- 28 people
- Sponsor
- Marwa Hisham Mohamed Salah Eldin
Necrotic Pulp
Evaluation of Pain Relief and Bacterial Reduction After Using Calcium Hydroxide With Mesoporous Silica Nanoparticles as an Intracanal Medicament in Necrotic Mandibular Molars: A Randomized Controlled Clinical Trial
This study compares how well different root canal medications reduce pain and bacteria after treatment of lower molar teeth with necrotic pulp.
- Trial name
- NCT07327996
- Testing
- Calcium Hydroxide Intracanal medication, mesoporous silica nanoparticles paste, Calcium Hydroxide + mesoporous silica nanoparticles
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Chronic Pain, Widespread, Obesity
Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults
The goal of this observational study is to learn if surgical weight loss can improve chronic widespread pain in people living with higher BMI who self-identify as Hispanic/Latino ethnicity or non-Hispanic Black based on the…
- Conditions
- Chronic Pain, Widespread, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT06795386
- Testing
- Bariatric Surgery
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- New York University
Preventing Propofol Pain on Injection
Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain
Propofol is the most popular IV anaesthetic agent used for induction, however one of its known side effects is causing pain on injection, the gold standard method in preventing this pain is using lidocaine prior to injecting…
- Trial name
- NCT07116304
- Testing
- Lidocaine, a local anaesthetic., Parecoxib 40mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Back Pain
Health Effects of Mindfulness Based Stress Reduction Course in Treatment of Back Pain
Health effects of mindfulness based stress reduction course versus usual care in treatment of back pain: a randomized clinical trial Mindfulness based stress reduction (MBSR) course intervention for half of the research patients…
- Trial name
- NCT07528833
- Testing
- Mindfulness based stress reduction (MBSR) course
- Where
- 4 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Tampere University Hospital
Bacterial Load Reduction, Postoperative Pain
Evaluation of Postoperative Pain and Bacterial Load After Hyalone or Calcium Hydroxide Medication in Mandibular First Molars
This randomized controlled clinical trial aims to evaluate the effect of Hyalone hydrogel compared with calcium hydroxide as an intracanal medicament on postoperative pain and bacterial load reduction in mandibular first molars…
- Trial name
- HYACAL-ENDO (NCT07775456)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt