Clinical trials: Reflex Sympathetic Dystrophy
Complex Regional Pain Syndrome
Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome
To demonstrate that spinal cord stimulator has an effect on sympathetic function (the one that give us the fight and flight response).
- Trial name
- CRPS (NCT00780390)
- Testing
- Autonomic Function Assessment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Pain
Neurophysiological Basis of Rehabilitation in Complex Regional Pain Syndrome, Type I and Chronic Low Back Pain
Complex Regional Pain syndrome Type I (CRPS-I) is a chronic progressive disease. Patients experience dramatic decline of overall well-being, despite the absence of any apparent physical cause.
- Trial name
- BrainEXPain (NCT02347579)
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
CRPS
Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA
The Department of Anesthesiology is conducting a clinical trial to evaluate if pregabalin given prior to and for several days after Total Knee Arthroplasty (TKA) will reduce the prevalence of Complex Regional Pain Syndrome (CRPS)…
- Trial name
- PregTKA (NCT00558753)
- Testing
- pregabalin
- Volunteers
- 240 people
- Sponsor
- Rush University Medical Center
Pain, Joint, Complex Regional Pain Syndromes
Pulsed Electromagnetic Fields (PEMFS) in Complex Regional Pain Syndrome Type i (CRPS-I) of the Foot (PeCFoA)
The investigators hypothesize that the association of I-ONE® therapy with standard rehabilitation treatment can optimize the clinical and functional recovery of patients with pulsed electromagnetic fields (PEMFs) (I-ONE® therapy)…
- Conditions
- Pain, Joint, Complex Regional Pain Syndromes, Ankle Disease, Foot Diseases
- Trial name
- (PeCFoA) (NCT05922618)
- Testing
- I-One
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Complex Regional Pain Syndrome
Evaluation of the Physiodoloris Pain Monitor in Patients With Complex Regional Pain Syndrome
A French University team (M. Jeanne, MD, and M. LOGIER, Ph D) have developed a pain assessment tool based on the analysis of the variability heart rate which evaluates the Analgesia Nociception Index (ANI).
- Trial name
- ANI-ALGO (NCT02663284)
- Testing
- Ropivacaine 0.5%
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hopital Foch
CRPS (Complex Regional Pain Syndrome) Type I
Ultrasound and Somatosensory Median Nerve Evaluation in CRPS I
Complex regional pain syndrome (CRPS) is a disorder falling within the sphere of neuropathic pain, characterised by a plethora of symptoms.
- Trial name
- MEDICUS (NCT06978608)
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb
Embodied Virtual Reality for Chronic Pain
Virtual reality creates interactive, multimodal sensory stimuli that have demonstrated considerable success in reducing pain. Much research so far has focused on VR's ability to shift patients' attention away from pain; however…
- Conditions
- Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb, Complex Regional Pain Syndrome I (CRPS I), Complex Regional Pain Syndrome I of Upper Limb
- Trial name
- NCT05160038
- Testing
- Embodied virtual reality
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University of Zurich
Complex Regional Pain Syndrome Type I
Phase 3, Open-Label Extension Study of AMBTX-01 (Neridronate) for Complex Regional Pain Syndrome Type 1
A Phase 3 open-label extension study of AMBTX-01 (neridronate) for Complex Regional Pain Syndrome Type 1
- Trial name
- NCT07857733
- Testing
- Neridronate
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Ambros Therapeutics, Inc.
Complex Regional Pain Syndrome
Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS
Complex Regional Pain Syndrome is a debilitating and extremely difficult to treat condition. There is a large body of evidence demonstrating the therapeutic value of N-methyl-D-aspartate (NMDA)-receptor antagonists in CRPS.
- Trial name
- NCT00579085
- Testing
- Ketamine, IV NSS, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Drexel University College of Medicine
Complex Regional Pain Syndrome, Type I
Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I
This clinical trial is being conducted to demonstrate the efficacy of neridronic acid in the treatment of pain associated with complex regional pain syndrome type I (CRPS-I).
- Trial name
- NCT02402530
- Testing
- Neridronic acid 62.5 mg
- Where
- 59 sites in United States, Germany and 1 more
- Volunteers
- 459 people
- Sponsor
- Grünenthal GmbH
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Complex Regional Pain Syndromes
TMS for Complex Regional Pain Syndrome
The aim of the current study is to assess the efficacy of TMS in the treatment of Complex Regional Pain Syndrome (CRPS). It is hypothesized that participants who receive TMS (Group 1) relative to sham treatment (Group 2) once…
- Trial name
- NCT03137472
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Reflex Sympathetic Dystrophy, Causalgia
Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror Therapy
AlgoMIR project born thanks to a meeting between pain professionals and re-education staff. The goal of this project is to develop and evaluate a program of learning with exercises by mirror therapy, that could be easily shared…
- Trial name
- AlgoMIR (NCT02667717)
- Testing
- Mirror therapy, Usual care
- Where
- 5 sites in France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Complex Regional Pain Syndrome Type I
Complex Regional Pain Syndrome in Children: Impact of Bergès Relaxation on the Autonomic Balance
Complex regional pain syndrome (CRPS) is a disease provoking chronic pain in the limbs, following a trauma. Patient care is complicated by the variable clinical picture and response to treatment.
- Trial name
- NCT03309774
- Testing
- questionnaires, holter electrocardiogram, blood pressure
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Complex Regional Pain Syndromes
The Use of Zoledronic Acid to Complex Regional Pain Syndrome
To evaluate the efficacy and the safety of using a single, intravenous 5mg dose of zoledronic acid in managing pain in Complex Regional Pain Syndrome patients.
- Trial name
- Aclasta (NCT01788176)
- Testing
- Zoledronic acid
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Complex Regional Pain Syndromes
Neuroimaging Study on the Effect of Transdermal Buprenorphine in Complex Regional Pain Syndrome Patients
In the present study, we aim to investigate the effect of buprenorphine on neuroinflammation in patients with complex regional pain syndrome, using [11C]-(R)-PK11195 PET.
- Trial name
- NCT03977012
- Testing
- Buprenorphine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Complex Regional Pain Syndrome, Chronic Pain
Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a rare and often debilitating chronic pain condition whereby individuals may experience extreme sensitivity, discoloration, and swelling of the affected area -- along with numerous other…
- Conditions
- Complex Regional Pain Syndrome, Chronic Pain, Causalgia, Complex Regional Pain Syndrome Type I
- Trial name
- LDN-CRPS (NCT06306157)
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hospital for Special Surgery, New York
Complex Regional Pain Syndrome, Type 1
A Study of the Effect of Lenalidamide on Complex Regional Pain Syndrome Type 1
The purpose of this study is to determine if lenalidomide is a safe and effective treatment for complex regional pain syndrome type 1 (CRPS).
- Trial name
- NCT00166452
- Testing
- Lenalidamide
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Stellate Ganglion Block, Cervical Epidural
Cervical Epidural and Stellate Ganglion Block in Upper Limb Complex Regional Pain Syndrome
Evaluate the efficacy of two regimens of management in relieving chronic refractory pain in patients with upper limb complex regional pain syndrome after orthopedic trauma
- Conditions
- Stellate Ganglion Block, Cervical Epidural, Complex Regional Pain Syndromes
- Trial name
- NCT05970146
- Testing
- Ultrasound guided Stellate ganglion block, unilateral cervical epidural
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Complex Regional Pain Syndromes, Healthy
Study of Proteins Associated With Complex Regional Pain Syndrome
This study will try to learn more about complex regional pain syndrome, or CRPS (previously known as reflex sympathetic dystrophy, spreading neuralgia, and sympathalgia), by examining the release of small proteins in the blood of…
- Trial name
- NCT00033969
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)