Clinical trials: Refractive Assessment, open to volunteers
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Cataract, Presbyopia
Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens
To assess the safety and effectiveness of the Juvene® IOL for the treatment of aphakia and mitigation of the effects of presbyopia after removal of the natural crystalline lens due to cataract.
- Trial name
- Nirvana (NCT05364983)
- Testing
- Juvene IOL, Tecnis® Monofocal (ZCB00, PCB00 or DCB00)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Myopia
Development of a New Device and Method to Assess the Degree of Myopia and/or Astigmatism in Myopic People
The purpose of this clinical investigation is to check whether the new device can correctly measure a person's degree of myopia and astigmatism.
- Trial name
- MDSW_DiVA2Rx (NCT07297810)
- Testing
- Optical correction values obtained with investigational device and visual acuity, Optical correction values obtained with an autorefractometer and visual acuity, Optical correction values obtained with a phoropter and visual acuity
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
A Controlled Evaluation of Optical Defocus Parameters on Transient Changes in Axial Length Using Kubota Glass
This study will assess the optimal performance characteristics of optical defocus on transient changes in axial length with Kubota Glass, using a randomized, double-masked, 5-treatment, 5-period crossover design with…
- Trial name
- NCT07686289
- Testing
- KG1, KG2, KG3
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Strabismus
Evaluation of a County-Based Eye Health Service Model in Rural Chinese Children
This project proposes to conduct a prospective, multicenter registry study in rural China to evaluate, under real-world conditions, the implementation effectiveness of an integrated child eye health service model centered at the…
- Conditions
- Myopia, Strabismus, Eye Health
- Trial name
- NCT07547748
- Testing
- School-based Eye Health Screening
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Juvenile Myopia, Myopia
Assessment of DOT Spectacles in Chinese Children Extension
This is a randomized, controlled, open-label, evaluator-blinded, multicenter, clinical trial of 12-months duration to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses in reducing…
- Trial name
- CATHAY Ext (NCT07008001)
- Testing
- Novel spectacle lens design
- Where
- 5 sites in China
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation
This study evaluates the safety and efficacy of a viscoelastic-free method for Implantable Collamer Lens(ICL) implantation to treat high myopia.
- Trial name
- NCT03059043
- Testing
- viscoelastic-free implantation system, standard viscoelastic-assisted Implantation system
- Where
- 5 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Myopia, Pre-myopia
A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control Spectacles
This study aims to find out whether ZEISS MyoActive lenses can help prevent short-sightedness from developing in children. We aim to recruit at least 50 children in total for this study.
- Trial name
- NCT07779941
- Testing
- Zeiss MyoActive lenses, Single Vision Lenses
- Where
- Singapore
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Refractive Errors
Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective Refraction
This study aims to evaluate the performance of an automated subjective refraction system that operates a digital phoropter. By comparing its results with those obtained through conventional subjective refraction performed by an…
- Trial name
- NCT07891897
- Testing
- Automated Program-Controlled Subjective Refraction, Optometrist-Performed Subjective Refraction
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Nearsightedness, Farsightedness
An Evaluation of LASIK, SMILE and PRK Surgery in Physicians
The principle investigator is evaluating self-reported quality of vision and quality of life in physicians undergoing LASIK, SMILE and PRK surgery.
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT02576483
- Testing
- Questionnaire (QoV questionnaire)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Stanford University
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Soft Contact Lenses
A Clinical Trial Assessing the Efficacy and Safety of ST-1 Silicone Hydrogel Daily Disposable Soft Contact Lenses Compared to Miru 1day UpSide
This study will enroll 63 eligible subjects (126 eligible eyes, complete at least 108 evaluable eyes) in approximately 6 different medical centers in Taiwan, in order to evaluate the efficacy and safety of ST-1 silicone hydrogel…
- Conditions
- Myopia, Soft Contact Lenses, Daily Disposable Soft Contact Lenses
- Trial name
- NCT07345416
- Testing
- ST-1, Miru 1day UpSide
- Where
- 6 sites in Taiwan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Physical Fitness
Influence of Strength Training on Myopia Care in Kindergarten Children
With the advancement of technology and changes in lifestyle, the physical activity levels of modern children have gradually decreased.
- Conditions
- Myopia, Physical Fitness, Muscle Strength
- Trial name
- NCT07121049
- Testing
- Strength training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Myopia, Myopia, Progressive
Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.
Phase III clinical study to evaluate the efficacy of Alleance® (atropine sulfate 0.01%) ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in…
- Trial name
- NCT06389110
- Testing
- Alleance®
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care
Recruitment of Participants
Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality in Cataract Patients
This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical Cataract diagnosis and treatment.
- Trial name
- NCT04833491
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine