Clinical trials: Refractive Assessment, open to volunteers
Myopia: Refractive Error
Evaluation of Novel Spectacles Intended for Myopia Management in a Short-Term Study
The primary objective of this study is to evaluate the visual acuity, wearability, and quality of vision with two novel multifocal glasses designs in habitual myopia control glasses wearers, in a non-dispensing study after…
- Trial name
- NCT07497672
- Testing
- Habitual myopia glasses, Myopia Glasses A, Myopia Glasses B
- Volunteers
- 20 people
- Sponsor
- Myoptechs, Inc
Intraocular Lens, Cataract
Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic
Cataracts are cloudy areas in the lens of the eye that can cause changes in vision. Symptoms of cataracts include cloudy or fuzzy vision and sensitivity to glare.
- Conditions
- Intraocular Lens, Cataract, Presbyopia
- Trial name
- NCT05955846
- Testing
- cataract surgery, implantation of device IOL FG-80030.1
- Where
- 8 sites in Portugal, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Z Optics, Inc.
Refractive Disorders
Evaluation of the Effects of Virtual Reality on Preoperative Anxiety in Refractive Surgery
The objective of this study is to determine to what extent the use of a software application prior to refractive surgery involving multisensory immersion (visual and auditory) in a hypnotic and relaxing sound and visual…
- Trial name
- ERVAN (NCT07050498)
- Testing
- Virtual reality, Usual Care Group
- Where
- France
- Volunteers
- 68 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Soft Contact Lenses
A Clinical Trial Assessing the Efficacy and Safety of ST-1 Silicone Hydrogel Daily Disposable Soft Contact Lenses Compared to Miru 1day UpSide
This study will enroll 63 eligible subjects (126 eligible eyes, complete at least 108 evaluable eyes) in approximately 6 different medical centers in Taiwan, in order to evaluate the efficacy and safety of ST-1 silicone hydrogel…
- Conditions
- Myopia, Soft Contact Lenses, Daily Disposable Soft Contact Lenses
- Trial name
- NCT07345416
- Testing
- ST-1, Miru 1day UpSide
- Where
- 6 sites in Taiwan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Physical Fitness
Influence of Strength Training on Myopia Care in Kindergarten Children
With the advancement of technology and changes in lifestyle, the physical activity levels of modern children have gradually decreased.
- Conditions
- Myopia, Physical Fitness, Muscle Strength
- Trial name
- NCT07121049
- Testing
- Strength training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Myopia, Myopia, Progressive
Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.
Phase III clinical study to evaluate the efficacy of Alleance® (atropine sulfate 0.01%) ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in…
- Trial name
- NCT06389110
- Testing
- Alleance®
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Astigmatism
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
This study aims to evaluate the safety and effectiveness of femtosecond laser arcuate corneal relaxing incisions (AK) combined with Light Adjustable Lens (LAL) implantation for correcting pre-existing corneal astigmatism in…
- Trial name
- NCT07140653
- Testing
- Femto arcs, Light Adjustable Lens (LAL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Center For Sight
Myopia
Pivotal Study of SAT-001 in Treatment of Pediatric Patient With Myopia
The objective of this clinical investigation is to evaluate the efficacy and safety of SAT-001 designed as Software as Medical Device (SaMD) for slowing myopia progression and treatment in pediatric myopia patients.
- Trial name
- NCT06344572
- Testing
- SAT-001, Single vision spectacles
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Presbyopia
Evaluation of Refractive Outcomes in Patients Undergoing PRESBYOND Using the MEL90 Excimer Laser
The goal of this clinical trial is to collect information on vision outcomes in people aged 45 to 65 who have difficulty seeing clearly at near distances due to aging (a condition called presbyopia).
- Trial name
- NCT06960785
- Testing
- MEL90 excimer laser - PRESBYOND
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 75 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Postoperative Outcome Verification of Discrepant Toric IOL Calculator Recommendations After Cataract Surgery
The goal of this observational study is to learn which toric lens calculator best predicts the astigmatism remaining after cataract surgery in adults who received a TECNIS DIU toric intraocular lens (IOL) at Klinik Hietzing…
- Trial name
- NCT07880249
- Testing
- Standardized Postoperative Outcome Visit, Toric IOL Calculator Pathways (Exposure)
- Volunteers
- 128 people
- Sponsor
- Vienna Hospital Association
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Presbyopia
Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients
A multicenter, randomized, double-Blind, crossover, placebo-controlled Phase II clinical Study to evaluate the efficacy and safety of BRIMOCHOL PF and CARBACHOL PF in the treatment of Chinese patients with presbyopia.
- Trial name
- NCT06948357
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care
Cataract
Performance of Large Language Models for Structured Recognition and Refractive Prediction
We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images.
- Trial name
- NCT07183891
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jin Yang
Recruitment of Participants
Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality in Cataract Patients
This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical Cataract diagnosis and treatment.
- Trial name
- NCT04833491
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Presbyopia Correction, Presbyopia
Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match
The purpose of the study is to evaluate the binocular clinical endpoints of distance, intermediate, and near vision and patient reported outcomes utilizing mini-monovision versus mix-match approaches for the correction of…
- Conditions
- Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
- Trial name
- NCT07860567
- Testing
- TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Dr. Daniel H. Chang, MD
Myopia
Assessment of the Efficacy and Safety of a DYnaMic Peripheral DegradatiON Myopia Disorder Control in Myopic Children ״DYMOND Study״
The DYMOND study evaluates the safety and effectiveness of TrackSight™, a digital medical application designed to slow myopia (nearsightedness) progression in children during everyday screen use.
- Trial name
- DYMOND (NCT07390500)
- Testing
- TrackSight
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- NovaSight
Astigmatism, Myopia
Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers
To compare the performance of two leading soft multifocal Toric contact lenses.
- Trial name
- NCT07829419
- Testing
- Lens A ( comfilcon A), Lens B ( lehfilcon A)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)