Clinical trials: Refractive Error - Myopia
Juvenile Myopia, Myopia
Assessment of DOT Spectacles in Chinese Children
This is a randomized, controlled, evaluator-blinded, multicenter, two-arm parallel group clinical trial to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses by comparing to single…
- Trial name
- CATHAY (NCT05562622)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 5 sites in China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Presbyopia, Near Vision
Comparative Study and Validation of New Methodologies for Measuring Addition
The aim of this research is to collect comprehensive data on a presbyopic population that may require near vision correction, in order to identify the most useful tests to accurately determine the value of an addition.
- Conditions
- Presbyopia, Near Vision, Refraction Error
- Trial name
- NCT06963138
- Testing
- Visual Acuity, Objective refraction, Standard Subjective refraction
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Essilor International
Hyperopia, Myopia
Clinical Study of Visibility Tinted Clariti Contact Lens
The purpose of this study was to investigate the safety and efficacy of the Sauflon Clariti Monthly silicone hydrogel contact lenses with handling tint (Sauflon Pharmaceuticals Limited) by comparison with Air Optix Aqua silicone…
- Trial name
- NCT01996787
- Testing
- Air Optix Aqua, Clariti with Handling Tint
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sauflon Pharmaceuticals Ltd
Presbyopia
Open Label, Multi-center, Phase I Study of TECLens Quantitative Refractive Crosslinking in Presbyopia-Aged Patients.
An 'on-eye' UV delivery system for corneal crosslinking can be used safely and effectively to help free presbyopic patients from the need for reading glasses.
- Trial name
- NCT07208604
- Testing
- Quantitative refractive crosslinking
- Where
- Philippines
- Volunteers
- 25 people
- Sponsor
- TECLens, Inc.
Myopia, Myopia Progression
Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With Myopia
The purpose of this clinical trial is to compare a new myopia control spectacle lens with a standard single vision spectacle lens in slowing the progression of myopia (nearsightedness) in healthy children aged 6 to under 11…
- Trial name
- PEARL (NCT07839091)
- Testing
- Investigational Myopia Control Spectacle Lens, Single Vision Spectacle Lens
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
A Comparison of Silicone Hydrogel Contact Lenses: AIR OPTIX® COLORS Versus AIR OPTIX® AQUA
The purpose of this study was to compare the overall fit of AIR OPTIX® COLORS to AIR OPTIX® AQUA contact lenses.
- Trial name
- NCT01635920
- Testing
- Lotrafilcon B contact lens with color, Lotrafilcon B contact lens
- Volunteers
- 258 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
Presbyopic Supracor Treatment for Near Myopic/Hyperopic Pseudophakic Eyes
This clinical study has been planned to determine the effectiveness of a special laser treatment intended to correct both near and distance vision in patients who have undergone previous cataract surgery.
- Conditions
- Myopia, Hyperopia, Presbyopia
- Trial name
- SUPRACOR (NCT01387360)
- Testing
- Supracor
- Where
- Philippines
- Volunteers
- 33 people
- Sponsor
- Technolas Perfect Vision GmbH
Myopic Astigmatism
Efficacy and Safety of CLEAR in Myopia and Astigmatism in Chinese Population
In this multicenter, prospective, interventional, single-arm clinical trial, the aim is to determine safety and efficacy of CLEAR using the FEMTO LDV Z8 in Chinese patients in China.
- Trial name
- NCT05229133
- Testing
- CLEAR
- Where
- 4 sites in China
- Volunteers
- 215 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Refractive Errors, Myopia
Air Optix® Night and Day® Aqua Daily Wear
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix® Night and Day® Aqua (AONDA) contact lenses in a real-world setting when worn as daily wear for vision…
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT05976750
- Testing
- Lotrafilcon A contact lenses, Balafilcon A contact lenses
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Alcon Research
Myopia
Multi-Centre Clinical Evaluation Of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance for handling of two daily disposable contact lenses, stenfilcon A and etafilcon A.
- Trial name
- NCT01707238
- Testing
- etafilcon A, stenfilcon A
- Where
- 7 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Choroidal Neovascularization, Myopia, Degenerative
Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopia
The objectives of this study are to evaluate the safety and efficacy of 3 dose groups (27, 36 and 45 mg/m2) of Combretastatin A-4 Phosphate for the treatment of subfoveal choroidal neovascularization in subjects with pathologic…
- Trial name
- NCT01423149
- Testing
- Combretastatin A-4 Phosphate
- Volunteers
- 23 people
- Sponsor
- Mateon Therapeutics
Myopia
Clinical Comparison of Two Daily Disposable Silicone Hydrogel Soft Contact Lens
The objective of this study is to evaluate a new daily disposable silicone hydrogel soft contact lens by comparing to an existing daily disposable soft contact lens.
- Trial name
- NCT02676258
- Testing
- Si-Hy (olifilcon B), Vistakon (narafilcon A)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Visco Vision Inc.
Myopia
Silicone Hydrogel Soft Contact Lens 7-Day Extended Wear Basis
The objective of this study is to evaluate the safety and effectiveness of the Bausch + Lomb samfilcon A soft (hydrophilic) contact lens, a new silicone hydrogel contact lens, compared to the Bausch + Lomb PureVision® soft…
- Trial name
- NCT02939950
- Testing
- Bausch + Lomb Samfilcon A Soft Contact Lens, Bausch + Lomb Pure Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Myopia, Astigmatism
Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure
The objective of the post-approval study (PAS) is to assess patient experience of visual symptoms 6 months after bilateral treatment with the VisuMax SMILE procedure as measured by a patient questionnaire.
- Trial name
- NCT05740293
- Testing
- VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
- Where
- 7 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Myopia
Clinical Evaluation Of Two Daily Disposable Contact Lenses And A Monthly Replacement Lens
The objective of the study is to compare the clinical performance of silicone hydrogel daily disposable contact lenses, conventional hydrogel daily disposable contact lenses and silicone hydrogel monthly replacement contact…
- Trial name
- NCT01151371
- Testing
- narafilcon B contact lens, nelfilcon A contact lens, lotrafilcon B contact lens
- Where
- 28 sites in United States
- Volunteers
- 452 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Evaluation of Stenfilcon A Contact Lenses
This study is to evaluate the fitting performance of stenfilcon A contact lens (test) compared to narafilcon A contact lens (control).
- Trial name
- NCT03471832
- Testing
- stenfilcon A lens, narafilcon A lens
- Where
- 4 sites in Japan
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Comparison of Two Daily Disposable Lenses Among Daily Disposable Lens Wearers
The primary objective of this trial is to evaluate the subjective performance of two different daily disposable contact lenses in a population of daily disposable lens wearers.
- Trial name
- NCT01134211
- Testing
- nelfilcon A, filcon II 3
- Where
- Germany
- Volunteers
- 316 people
- Sponsor
- CIBA VISION
Myopia
Clinical Performance of Existing Wearers of Avaira Sphere Following a Refit With Clariti Elite Sphere
The aim of this dispensing study is to evaluate the clinical performance of existing wearers of Avaira sphere lenses following a refit with Clariti Elite sphere over 4 weeks of daily wear.
- Trial name
- NCT02248727
- Testing
- somofilcon A
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn continuously for up to 1 week.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04403542
- Testing
- Lehfilcon A contact lens, Comfilcon A contact lens
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research