Clinical trials: Refractive Error - Myopia
Myopia, Children
Study of Atropine Therapeutic Effect on Myopic Progression
This study is to evaluate the therapeutic effect and safety of LPTAT in children with myopia.
- Trial name
- STAMP (NCT05529056)
- Testing
- Atropine Sulfate 01, Atropine Sulfate 02, Atropine Sulfate 03
- Where
- 15 sites in South Korea
- Volunteers
- 472 people
- Sponsor
- LitePharmTech Co., Ltd.
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Myopia
Evaluation of Visual Performance With Contact Lenses
This study will evaluate the influence of contact lens optical design on visual performance using standard and multifocal soft contact lenses (MFCLs).
- Trial name
- NCT03705130
- Testing
- Single Vision Contact Lens, Multifocal Contact Lens 1, Multifocal Contact Lens 2
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Houston
Myopia
The Effect of Blue-light Filtering Spectacle Lenses on Myopia Progression in Schoolchildren
The purpose of this study is to investigate if the blue-light filtering spectacle lenses promote myopia progression in schoolchildren.
- Trial name
- NCT03538002
- Testing
- Blue-light filtering spectacle lenses
- Where
- Hong Kong
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Efficacy of Repeated Low-level Red-light Therapy in Myopia Control
Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of exposure to induce the myopia control…
- Trial name
- NCT05606237
- Testing
- Low-level Red Light Therapy Device
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Myopia, Refractive Error
An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic Children
The goal of this research study is to understand the wearing experience of A.M.L. series of lenses in myopic children. The main questions it aims to answer are: How quickly and effectively children adapt to the A.M.L.
- Trial name
- NCT07354945
- Testing
- A.M.L. Series of Lenses
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Essilor International
Myopia, Myopic Astigmatism
A Study of Artificial Intelligence Assisted Small Incision Lenticule Extraction (SMILE) for Surgical Design and Influencing Factors
The goal of this observational study is to learn about the difference of refractive outcomes between Artificial Intelligence and experienced surgeon predicting Nomogram assist SMILE surgical design and the influenced factors of…
- Trial name
- NCT06229301
- Testing
- AI-predicted Nomogram
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Tianjin Eye Hospital
Myopia, Refractive Ametropia
Comparison of Two Rotational Alignment Methods for Astigmatism Correction in SMILE Surgery
Small incision lenticule extraction (SMILE) is a commonly used corneal refractive procedure for correcting myopia and myopic astigmatism.
- Trial name
- NCT07696468
- Testing
- Device-assisted cyclotorsion control during SMILE, Manual limbal marking-guided cyclotorsion adjustment during SMILE
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Astigmatism
Technolas 217z Laser With Zyoptix Aspheric Algorithm Used for the LASIK Treatment of Myopia and Myopic Astigmatism.
The purpose of this study is to evaluate the safety and effectiveness of the Bausch \& Lomb Technolas 217z laser with the investigational Zyoptix Aspheric Algorithm when used for LASIK treatment of myopia and myopic astigmatism.
- Trial name
- NCT00769808
- Testing
- Bausch & Lomb 217z Excimer Laser
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Family Myopia Study
This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work.
- Trial name
- NCT00341549
- Where
- United States
- Volunteers
- 7,477 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Nearsightedness, Near Sightedness
The Safety and Efficacy of SYD-101 in Children With Myopia
Myopia, or nearsightedness, is the most common eye disorder, often affecting more than 40% of adults in Europe, Asia and the USA.
- Conditions
- Nearsightedness, Near Sightedness, Near-sightedness
- Trial name
- STAR (NCT03918915)
- Testing
- SYD-101 0.01%, SYD-101 0.03%, Vehicle
- Where
- 47 sites in United States, Austria and 1 more
- Volunteers
- 852 people
- Sponsor
- Sydnexis, Inc.
Myopia, Hyperopia
Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
This purpose of this study is to evaluate the safety and effectiveness of a topography-based custom ablation treatment using the ALLEGRETTO WAVE® Eye-Q 400 Hz laser system for treating myopia and hyperopia.
- Trial name
- NCT01028378
- Testing
- T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
- Where
- 10 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Research Consultants, Inc.
Myopia, Myopic Astigmatism
Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)
This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian® Implantable Collamer® Lens (ICL) in study participants who have a diagnosis of myopia or myopia with…
- Trial name
- NCT04283149
- Testing
- EVO/EVO+ Visian ICL
- Where
- 14 sites in United States
- Volunteers
- 327 people
- Sponsor
- Staar Surgical Company
Cataract, Refractive Errors
Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery
The two main objectives of this study are to demonstrate safety and effectiveness of implanting the PanOptix Trifocal IOL in patients who have had previous myopic Lasik.
- Trial name
- NCT04698278
- Testing
- PanOptix Trifocal Intraocular Lens
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Parkhurst NuVision Clinical Research LLC
Myopia, Astigmatism
Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter
To evaluate the clinical performance and user-reported experience of Paragon CRT contact lenses with a 5mm Optic Zone Diameter (OZD)
- Trial name
- NCT07751172
- Testing
- Lens A (paflufocon D)
- Where
- 3 sites in United States, Spain
- Volunteers
- 70 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Progressive
Novel Lenses for Myopia Progression Trial
This is a multi-center , prospective, randomised, longitudinal study to evaluate rate of myopia progression with novel lenses compared to Single-Vision spectacles.
- Trial name
- NCT06563700
- Testing
- spectacle lens, single vision lens
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Ametropia, Hyperopia
Air Optix Night and Day Aqua (AONDA) Retrospective Study 1
The purpose of this study is to assess long term performance and safety of AONDA in a real world setting when worn as daily wear or continuous wear for vision correction.
- Conditions
- Refractive Ametropia, Hyperopia, Myopia
- Trial name
- NCT05790928
- Testing
- Lotrafilcon A spherical contact lenses
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- Alcon Research
Myopia
Evaluation of Corneal Irregular Astigmatism and Visual Quality Following Bilateral Sequential Small Incision Lenticule Extraction (SMILE) and Laser Subepithelial Keratomileusis (LASEK): A Six-Year Comparative Study
To compare the corneal spherical component (SC), regular astigmatism (RA), irregular astigmatism (IA, including Asymmetry and Irregularity) and visual quality six years after small incision lenticule extraction (SMILE) and laser…
- Trial name
- SMILE LASEK (NCT06673992)
- Testing
- This study does not involve any interventions
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Shanghai 10th People's Hospital
Progressive Myopia, Pediatric Myopia
Efficacy of Different Interventions for Progressive Myopia After Orthokeratology Lens Wear
Myopia has emerged as a significant concern impacting the visual health of children and adolescents on a global scale. According to research conducted by Holden BA et al., it is projected that by the year 2050, the worldwide…
- Conditions
- Progressive Myopia, Pediatric Myopia, Orthokeratology-related Myopia Progression
- Trial name
- NCT07494799
- Testing
- OK Lens Continuation Group, OK Lens + 0.01% Atropine Group, OK Lens with Reduced Optical Zone Group
- Volunteers
- 3,890 people
- Sponsor
- Tianjin Medical University Eye Hospital
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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