Clinical trials: Refractive Error - Myopia
Myopia
The Effect of Hinge Position and Hinge Width on Corneal Sensation and Dry Eye After IntraLase LASIK Procedure
Corneal sensation is known to play a role in tear secretion. Decreased sensation leads to decreased tear production; and when bilateral, leads to a decreased blink rate as well. Dry eyes are a common side effect of LASIK.
- Trial name
- IDES (NCT00803478)
- Testing
- LASIK
- Where
- United States
- Sponsor
- University of Michigan
Myopia
Vistakon Investigational Contact Lenses Worn for Daily Wear
This study compares the performance of an investigational contact lens to a currently marketed lens.
- Trial name
- NCT00717249
- Testing
- galyifilcon A control lens, galyfilcon A with a silver additive
- Where
- 20 sites in United States
- Volunteers
- 529 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT00762970
- Testing
- Test Lens 1, Test Lens 2, Control Lens
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Efficacy of PEG-400 and Systane Artificial Tears (Alcon) on Quality of Vision
To evaluate the effect of PEG-400 and Systane on quality of vision after LASIK.
- Trial name
- NCT00627302
- Testing
- PEG-400, Systane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Myopia, Astigmatism
Photorefractive Keratectomy (PRK) : Comparison of Corneal Haze Between Two Modes of De-epithelialisation (Laser Versus Manual Alcohol)
surgical correction of ametropia. A number of improvements have been introduced to overcome the side effects and complications such as corneal haze, epithelial irregularities induced by wound healing, pain and delayed visual…
- Trial name
- H-TransPKR (NCT05072977)
- Testing
- TransPRK, Alcohol PRK
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Myopia, Progressive
Crossover RCT of TAMER Lenses in Myopia Control
This study is a prospective, randomized, crossover clinical trial with a planned proposed enrollment of 120 Chinese male and female subjects aged 6-12 years without systemic or ocular diseases to follow up their cycloplegic…
- Trial name
- NCT06329986
- Testing
- TAMER Lens Spectacle, SV lenses
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Errors, Myopia
Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn continuously for up to 1 week.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04403542
- Testing
- Lehfilcon A contact lens, Comfilcon A contact lens
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate the Safety and Efficacy of Eye Secret UV Aspheric Silicone Soft (Hydrophilic) 1Day Color Contact Lens
This was a prospective, randomized, open label, parallel, active-controlled clinical study to assess the safety and efficacy of Silicone Color Contact Lens for vision correction.
- Trial name
- NCT06527586
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 131 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Myopia
Dispensing Overnight Study in Lenses
The purpose of the study is to evaluate the fit and performance of an investigational soft contact lens in comparison with a currently marketed lens.
- Trial name
- NCT00349856
- Testing
- Biofinity
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Myopia Control Using Bright Light Therapy, Myopic Defocus and Atropine
The purpose of the study is to investigate the effect of bright light therapy, myopic defocus, atropine and the combination in myopia control in schoolchildren.
- Trial name
- NCT04923841
- Testing
- High intensity light box for bright light therapy and single vision spectacle lenses, High intensity light box for bright light therapy and Defocus Incorporated Multiple Segments (DIMS) spectacle lenses, High intensity light box for bright light therapy and atropine 0.01% eye drop and and single vision spectacle lenses
- Where
- Hong Kong
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Refractive Errors
Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens
The objective of this clinical investigation is to collect valid scientific safety and effectiveness data on the Acuity 200 (fluoroxyfocon A) Rigid Gas Permeable Contact Lens, manufactured from a newly developed rigid gas…
- Trial name
- Acuity 200 (NCT03971227)
- Testing
- Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
- Where
- 3 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Acuity Polymers, Inc.
Myopia, Juvenile Myopia
Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens
This is a conventional efficacy trial to validate the results from previous clinical trials for younger children; the 12-month efficacy results will be used to predict the 3-year treatment efficacy.
- Conditions
- Myopia, Juvenile Myopia, Myopia Progression
- Trial name
- EUCALYPTUS (NCT06034327)
- Testing
- Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
- Where
- 14 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
1 Week Crossover Study Between Two Soft Contact Lenses
The objective of this investigation is to compare the visual clinical performance of two daily disposable soft contact lenses.
- Trial name
- NCT06611410
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Myopia
Eye Length Signal With Myopia Control
Myopia, considered as a global epidemic, is rapidly rising in prevalence especially in east Asian countries. Younger ages are associated with greater annual progression and thus early onset myopia is likely to result in higher…
- Trial name
- NCT04813640
- Testing
- Spectacles
- Where
- Vietnam
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision Institute
Myopia
Clinical Validation of the Apollo Daily Disposable Soft Contact Lenses
The purpose of this study was to confirm the design specifications of a Test lens and validate its clinical performance.
- Trial name
- NCT05035017
- Testing
- Test Lens, Control Lens
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess the comfort of OPTI-FREE RepleniSH in soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01211535
- Testing
- OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Quality of Vision and Quality of Life With LASIK
The investigators are administering a validated questionnaire looking at patient reported quality of life and quality of vision after LASIK surgery
- Conditions
- Myopia, Astigmatism, Quality of Lifte
- Trial name
- NCT02161263
- Testing
- Patient Quality of Life andVision after LASIK Surgery
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Edward E. Manche
Corneal Disease, Pterygium
Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell Transplantation
Corneal disease is a leading cause of blindness in the world. A shortage of corneal donor tissue has prevented many patients from regaining vision.
- Conditions
- Corneal Disease, Pterygium, Myopia, Hyperopia
- Trial name
- NCT02148016
- Testing
- LSCs and amniotic membrane (Modified Technique), Amniotic membrane only (Traditional Technique), PRK, LSCs, and amniotic membrane (Modified Technique)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Myopia
Correction of Myopia Evaluation Trial 2
The purpose of the study is to determine if progressive addition lenses (PALs) versus single vision lenses (SVLs) slow the progression of low myopia in children with poor accommodative responses (i.e., large accommodative lags)…
- Trial name
- COMET2 (NCT00320593)
- Testing
- Progressive Addition Lenses (PALs), Single Vision Lenses (SVLs)
- Where
- 8 sites in United States
- Volunteers
- 118 people
- Sponsor
- Jaeb Center for Health Research
Myopia
Evaluation of the Feasibility a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of an investigational contact lens.
- Trial name
- NCT01309906
- Testing
- Investigational lens, Air Optix Aqua lens
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
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