Clinical trials: Refractive Error - Myopia
Myopia, Degenerative
Reduced-fluence Verteporfin Photodynamic Therapy Plus Ranibizumab for Choroidal Neovascularization in Pathologic Myopia
To demonstrate the efficacy of ranibizumab in combination with reduced-fluence verteporfin photodynamic therapy (RF-PDT) in patients with subfoveal choroidal neovascularization secondary to pathologic myopia (PM).
- Trial name
- NCT01968486
- Testing
- PDT standard fluence, ranibizumab, PDT reduced fluence, ranibizumab, ranibizumab
- Volunteers
- 60 people
- Sponsor
- University of Campania Luigi Vanvitelli
Myopia
Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain
The objective of this study was to investigate the impact of employing bandage contact lenses with a base curve of 8.4 mm versus 8.8 mm on visual recovery following Trans-PRK in patients characterized by steep corneas and high…
- Trial name
- NCT06393855
- Testing
- single-step Trans-PRK, Placing a bandage contact lens on the cornea, with an 8.4-mm base curve in right eye and one with an 8.8-mm base curve in the left eye., Placing a bandage contact lens on the cornea,A contact lens placed on the cornea, with an 8.8-mm base curve in right eye and one with an 8.4-mm base curve in the left eye.
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Dongyang People's Hospital
Myopia, Progressive
Double Helix Design Defocus Lens Spectacle (RACE) for Myopia Control
This study uses 1.585 double helix defocus lens PC lenses with a unique optical design that includes a globally coherent visible area and complementary left and right helices that can form clear images.
- Trial name
- NCT05894382
- Testing
- Double Helix Design Defocus Lens Spectacle (RACE), single-vision spetacle lens
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, High-Grade, Myopia; Refractive Error
AOSLO-Based Precise Measurement of Retinal Hemodynamics: Development and Application Assessment
Changes in retinal hemodynamics play a key role in the development of various eye diseases. Currently, mainstream hemodynamic evaluation techniques have low resolution and poor measurement accuracy, limiting their widespread…
- Trial name
- NCT07051317
- Volunteers
- 120 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Lacritin and Heparanase Levels in Human Tears After Laser Refractive Surgery
The purpose of this study is to measure tear lacritin and heparanase levels before and following surgery using a minimal risk procedure to collect tears from patients undergoing PRK or LASIK.
- Trial name
- NCT01049724
- Testing
- Tear collection
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Fort Belvoir Community Hospital
Myopia
A Study to Evaluate the Safety and Efficacy of DSFNC1 Soft Hydrophilic Contact Lenses and SiHy Color Soft Hydrophilic Contact Lenses
This project is an open, parallel, randomly controlled, and non-inferiority clinical trial of DSFNC1 soft hydrophilic contact lenses with SiHy color soft hydrophilic contact lenses.
- Trial name
- NCT06616480
- Testing
- BenQ Materials DSFNC1 soft hydrophilic contact lenses, Visco SiHy Color soft hydrophilic contact lenses
- Where
- China
- Volunteers
- 192 people
- Sponsor
- BenQ Materials Corporation
Myopia, Refractive Errors
DD T2 Daily Disposable Registration Trial
The purpose of this study is to evaluate the performance of the investigational verofilcon A contact lens compared to the commercially available delefilcon A contact lens, by assessing visual acuity as the primary variable.
- Trial name
- NCT03305770
- Testing
- verofilcon A contact lenses, delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 107 people
- Sponsor
- Alcon Research
Refraction Error, Myopia
Age and Refraction in Predicting Myopia Progression in COVID-19
To determine the longitudinal changes of age and refraction in predicting myopia progression with risk under the coronavirus disease 2019 (COVID-19) pandemic in a 3-year follow-up of a Chinese cohort.
- Trial name
- NCT05305274
- Testing
- screening
- Where
- China
- Volunteers
- 34,400 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Myopia
Pilot Study to Assess the Efficacy of Short Exposure to Defocus to Slow the Progression of Myopia in Children
The objective of this pilot study is to establish whether brief periods of high levels of acutely imposed myopic defocus can be used to slow the progression of myopia in children, as measured by changes in spherical equivalent…
- Trial name
- NCT00400140
- Testing
- Hyperopic lens
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Refractive Error
A PHASED, PROSPECTIVE, MULTI-CENTER STUDY OF THE ELITA SYSTEM
This study will be a 2-phase, prospective, multicenter, open-label, non-comparative, non-randomized clinical investigation to confirm the safety and effectiveness of the ELITA system.
- Trial name
- NCT05713253
- Testing
- ELITA System
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Error - Myopia Simple
Evaluation of the Safety and Efficacy of PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3)
The goal of this clinical trial is to learn if PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3) are safe and effective for vision correction in adults.
- Trial name
- NCT06995781
- Testing
- Experimental Intervention, Active Comparator Intervention
- Volunteers
- 69 people
- Sponsor
- Pegavision Corporation
Myopia
Two Daily Disposable Contact Lenses in Symptomatic Patients
The purpose of this study is to evaluate the performance of DAILIES TOTAL1® and ACUVUE OASYS® 1-DAY and with respect to visual acuity in a symptomatic study population of monthly or bi-weekly replacement lens wearers.
- Trial name
- NCT03628599
- Testing
- Delefilcon A contact lenses, Senofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 39 people
- Sponsor
- Alcon Research
Myopia
Patient Reported Outcomes With WaveLight LASIK
This study is a multi-site, single-arm, ambispective, observational study of subject satisfaction, after successful bilateral LASIK surgery. Subjects will be assessed 12+ months post-operatively.
- Trial name
- NCT06668909
- Testing
- WaveLight® EX500
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- OVO LASIK + Lens
Myopia
Evaluation of Etafilcon A Daily Disposable Lenses
To evaluate the clinical performance of daily disposable etafilcon A lenses.
- Trial name
- NCT02061592
- Testing
- etafilcon A
- Where
- 7 sites in United States
- Volunteers
- 136 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Myopia, Astigmatism
LASIK iDesign vs SMILE
The study will compare the 6-month visual outcomes (i.e., visual acuity, contract sensitivity, higher order aberrations), quality of vision (i.e., double vision, glare, starburst, halos, etc.) and dry eye symptoms of patients…
- Trial name
- TG-LASIK vs SM (NCT07126756)
- Testing
- STAR S4 IR Excimer Laser System, VisuMax 400 Surgical Laser
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- 59th Medical Wing
Myopia, Large Language Model
Development and Validation of a Large Language Model-based Myopia Assistant System
Myopia is a rapidly growing global health concern, and there is an urgent need for advanced tools that can facilitate personalized healthcare strategies.
- Trial name
- NCT06607822
- Testing
- A patient-centered assistant system based on Large-Language Model (LLM)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Accomodation, Biofeedback Training
Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)
This study will examine the accommodative behavior in children undergoing myopia control treatments. A subset of children showing reduced accommodation, known to occur in while wearing multifocal soft contact lenses (MFCL) from…
- Conditions
- Accomodation, Biofeedback Training, Myopia
- Trial name
- NCT04807361
- Testing
- Auditory biofeedback traing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
650nm Low-level Red-light for Myopia Control and Prevention in Children
A multicenter randomized controlled trial, evaluating the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children.
- Trial name
- NCT05786586
- Testing
- 650 nm low-level red-light
- Where
- China
- Volunteers
- 572 people
- Sponsor
- Beijing Tongren Hospital
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