Clinical trials: Refractive Error - Myopia
Myopia, Astigmatism
Multi Laser Platform Comparison Study for LASIK
Comparison of LASIK outcomes using 3 different lasers and a total of 5 different treatment platforms.
- Trial name
- VBLWL-001 (NCT00770094)
- Testing
- Excimer Lasers, Excimer Laser for the LASIK procedure, Excimer Laser for LASIK
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Myopia, Mental Health
Intervention for Preventing Myopia and Multimorbidity in Children
This study aims to develop and evaluate a scalable, hybrid intervention model for the co-prevention of myopia, obesity, and mental health issues among children.
- Conditions
- Myopia, Mental Health, Cardiovascular Health Status
- Trial name
- NCT07294222
- Testing
- Standard School Health Education, Multi-component Health Promotion Package
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Myopia, Astigmatism
Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK
The purpose of this study is to compare LASIK outcomes using the WaveLight ALLEGRETTO WAVE™ wavefront guided or optimized excimer laser treatment with the AMO/VISX CustomVue™ and the LADARVision 4000 excimer laser treatment.
- Trial name
- WLCVLV-001 (NCT00821236)
- Testing
- Excimer Laser, AMO/VISX CustomVue™, LADARVision 4000 excimer laser
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Myopia, Refractive Errors
Prevalence and Environmental Factors for Myopia Among Chinese School-aged Children and Adolescent in Tianjin
The high prevalence of myopia has become a global public health problem. The study amied to investigate the prevalence and progression of myopia associated with social environmental factors in Tianjin, a Chinese megacity in north…
- Trial name
- NCT05336799
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia
To evaluate the efficacy of NeuroVision NVC vision correction technology to improve the vision of subjects with Low and Moderate Myopia in Asian eyes in Singapore
- Trial name
- NCT00348075
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Refractive Errors
Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities
Chinese children are some of the most short-sighted in the world, but only one in five children in poor areas who needs glasses has them.
- Trial name
- SWISH (NCT04077086)
- Testing
- Spectacles
- Where
- 3 sites in China, United Kingdom
- Volunteers
- 10,000 people
- Sponsor
- Queen's University, Belfast
Myopia
A One-Week Crossover Dispensing Evaluation of New Daily Wear Soft Contact Lenses
The purpose of this study is to validate the clinical performance of a new contact lens design when worn over a period 1 week compared to nelfilcon A (control).
- Trial name
- NCT03306641
- Testing
- Test Contact Lens, Nelfilcon A
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Progressive Myopia
MAD Trial: Myopia Atropine Dose
The goal of this interventional study is to compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment against progression of axial length in European children with progressive myopia, and to evaluate the safety…
- Trial name
- MAD (NCT05667454)
- Testing
- Atropine Ophthalmic 0.05%, Atropine Ophthalmic 0.5%
- Where
- 20 sites in Netherlands
- Volunteers
- 550 people
- Sponsor
- Erasmus Medical Center
Emmetropization, Myopia
Focus-out Glasses on Emmetropization in Chinese Children
The purpose of this study is to characterize the effects of peripheral focous-out glasses on emmetropization in non-myopic Chinese Children Aged 6-8 Years.This is a prospective, parallel-controlled randomized trial.
- Conditions
- Emmetropization, Myopia, Hyperopia
- Trial name
- NCT05689567
- Testing
- DEFOG glasses(peripheral focus-out glasses)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Myopia
WEAR (Wearability and Evaluation of Adjustable Refraction) III
Two-month randomized trial comparing three groups.
- Trial name
- WEARIII (NCT02529540)
- Testing
- Adjustable glasses, Custom standard glasses, Ready-made glasses
- Volunteers
- 324 people
- Sponsor
- Sun Yat-sen University
Myopia
Study on Safety and Efficacy of Focused LED-Based Red-Light Therapy in Myopic Adults
This research project is a prospective, single-arm, open-label pilot study designed to evaluate the efficacy and safety of focused LED-based repeated low-level red-light (fLED-RLRL) therapy in myopic adults.
- Trial name
- NCT07369804
- Testing
- fLED-based red-light therapy
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Effects of Blue of Glasses VS Standard Lenses on Contrast Sensitivity & Visual Fatigue in Myopic & Non-Myopic Adults
This study investigates the effects of blue light-blocking glasses compared to standard lenses on contrast sensitivity and visual fatigue in myopic and non-myopic adults.
- Trial name
- NCT06739525
- Testing
- Blue Light-Blocking Glasses (Intervention Group), Standard Lenses (Control Group)
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Superior University
Myopia
Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of three silicone hydrogel contact lenses over a 2 week period.
- Trial name
- NCT01244516
- Testing
- galyfilcon A, BC 8.30, lotrafilcon B, BC 8.60, comfilcon A, BC 8.60
- Where
- 35 sites in United States
- Volunteers
- 540 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors, Myopia
Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1
The primary objective of this study is to evaluate the overall performance of PRECISION1 contact lenses when compared to Biotrue ONEday contact lenses.
- Trial name
- NCT04527978
- Testing
- Verofilcon A contact lenses, Nesofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alcon Research
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Visual Outcomes And Contrast Sensitivity After Myopic Wavefront-Optimized Lasik With Nexisvision Shield Or Bandage Contact Lens
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK with a Nexisvision Shield or bandage contact lens placed postoperatively.
- Trial name
- NCT01706237
- Testing
- Nexisvision shield
- Volunteers
- healthy volunteers welcome
- Sponsor
- Durrie Vision
Myopia
Effect of Plum-blossom Needle vs. Tropicamide Eye Drops on Juvenile Myopia
The purpose of this study is to determine whether plum-blossom needle is effective in the treatment of juvenile myopia and compare the efficacy with Tropicamide Eye Drops.
- Trial name
- NCT03097198
- Testing
- Plum-blossom Needle, Tropicamide Eye Drops
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Wenzhou Medical University
Myopia, Cataract
Influence of Posterior Vitreous Detachment on Retinal Detachment After Lens Surgery in Myopic Eyes
Phacoemulsification with implantation of posterior chamber lenses represents the gold standard of care for patients needing lens surgery, but there is an increased risk of developing pseudophakic retinal detachment after surgery.
- Conditions
- Myopia, Cataract, Pseudophakic Retinal Detachment, Refractive Lens Exchange
- Trial name
- MYOPRED (NCT03152747)
- Where
- Austria
- Volunteers
- 609 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Presbyopia, Near Vision
Comparative Study and Validation of New Methodologies for Measuring Addition
The aim of this research is to collect comprehensive data on a presbyopic population that may require near vision correction, in order to identify the most useful tests to accurately determine the value of an addition.
- Conditions
- Presbyopia, Near Vision, Refraction Error
- Trial name
- NCT06963138
- Testing
- Visual Acuity, Objective refraction, Standard Subjective refraction
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Essilor International
Macular Hole, Myopia
Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent
Macular hole (MH) is a common condition that affects approximately 1.6/1000 elderly Chinese population. The prevalence is expected to be even higher in individuals with high myopia (HM), an established risk factor for MH.
- Trial name
- NCT07129798
- Testing
- ILM flap with no endotamponade technique
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
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