Clinical trials: Refractive Error - Myopia
Myopia
Myopia Control Using Optimized Optical Defocus RCTs
The aims of the study is to evaluate whether the DISC3.5 Plus contact lens will slow myopia progression and axial length growth in myopic children as compared with single vision soft contact lenses.
- Trial name
- NCT03681366
- Testing
- DISC3.5 plus
- Where
- China
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Investigating the Safety and Effect of Overnight Orthokeratology and Its Influencing Factors
To investigate the Safety and Effect of Overnight Orthokeratology and Its Influencing Factors in China
- Trial name
- NCT04910451
- Testing
- No Intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Myopia, Astigmatism
Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax
The purpose of this study is to compare Topography Guided Laser In Situ Keratomileusis (LASIK) corneal surgery to Small Incision Lenticule Extraction (SMILE) corneal surgery for the treatment of myopia with astigmatism.
- Trial name
- NCT02987660
- Testing
- Topography Guided LASIK, Small Incision Lenticular Extraction, WaveLight EX500 Excimer Laser System
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Alcon, a Novartis Company
Myopia
A Prospective, Randomized, Double-blind, Parallel, Active-controlled Clinical Study of Silicone Hydrogel Monthly Soft Contact Lens for the Safety and Effectiveness in Visual Correction.
This was a prospective, randomized, double-blind, parallel, active-controlled clinical study to assess the safety and efficacy of Silicone Hydrogel Contact Lens for vision correction.
- Trial name
- NCT06121531
- Testing
- Soft Contact Lens
- Where
- 2 sites in Taiwan
- Volunteers
- 144 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.
- Trial name
- NCT03888469
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Visual Outcomes for Toric Efficacy Study
This is a crossover study of two types of contact lenses (toric orthokeratology and soft multifocals). Primary aims are to quantify correction of astigmatism, subjective and objective visual performance, aberrometry, peripheral…
- Trial name
- VOTE (NCT03728218)
- Testing
- Contact lenses (Orthokeratology), Contact lenses (Soft Multifocal)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Houston
Myopia
Effects of Autostereoscopic 3D Visual Training on Binocular Vision Function of Myopes
This study intends to conduct a relatively comprehensive binocular visual function examination and follow-up on two groups of myopic subjects, one receiving autostereoscopic 3D vision training and the other receiving 2D vision…
- Trial name
- NCT06266910
- Testing
- Visual training video
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops
Myopia is the most common refractive disorder in the world. Many strategies have been developed to control myopia in children. Among them, the instillation of low-concentration atropine eyedrops has been proven to be effective in…
- Trial name
- ATROSMART (NCT05062031)
- Testing
- Defocus Incorporated Multiple Segments® (DIMS®) lenses, Atropine 0.05% eyedrops, Monofocal lenses
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Myopia
The Clinical Comparison of Narafilcon A and Stenfilcon A Contact Lenses
This study aims to compare the clinical performance and subjective acceptance of the narafilcon A lens with the stenfilcon A lens when used on a daily wear, daily disposable basis.
- Trial name
- NCT02920970
- Testing
- narafilcon A, stenfilcon A
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
Myopia, or shortsightedness, is a multifactorial disorder, governed by environmental and genetic factors. Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades and affecting…
- Trial name
- MODERATO (NCT07028827)
- Testing
- 0.05% atropine eye drops, 0.025% atropine eye drops
- Where
- 11 sites in Albania, Italy and 3 more
- Volunteers
- 234 people
- Sponsor
- Ocus Innovation Ireland Limited
Glaucoma, Myopia
Morphological Changes of Ciliary Body and Trabecular Meshwork
Glaucoma is the leading cause of irreversible blindness worldwide. Although the pathogenesis remains unclear, pathologic increase in intraocular pressure (IOP) due to blocked aqueous outflow through the trabecular-Schlemm canal…
- Trial name
- NCT05352854
- Testing
- 0.5% pilocarpine eye drops
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yune Zhao
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
The purpose of this study is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of two different daily disposable contact lenses.
- Trial name
- NCT01035905
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens
- Volunteers
- 63 people
- Sponsor
- CIBA VISION
Myopia
Corneal Biomechanics Study
The goal of the study is to investigate relationship between the corneal response to a temporary increase in intraocular pressure and corneal mechanical properties.
- Trial name
- NCT03658239
- Testing
- Inversion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Myopia
Effect of Preoperative Pupil Size on Quality of Vision After Wavefront-Guided LASIK
The purpose of this study is to evaluate whether the size of the pupil has an effect on quality of vision in patients undergoing LASIK surgery.
- Trial name
- NCT00889941
- Testing
- LASIK
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Myopia
Comparison of Lens Care Regimens With a Silicone Hydrogel Lens (Emerald)
The purpose of the study is to evaluate and compare, on a daily wear basis, the performance of two contact lens care solutions when used with silicone hydrogel soft contact lenses with regards to comfort and dryness symptoms.
- Trial name
- NCT00520351
- Testing
- ClearCare, Optifree Replenish
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopic Traction Maculopathy
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
This prospective pilot study evaluates factors that predict outcomes after vitrectomy for myopic foveoschisis (MFS), a sight-threatening complication of high myopia that can lead to progressive visual loss, foveal detachment…
- Trial name
- NCT07774637
- Testing
- pars plana vitrectomy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Nearsightedness, Farsightedness
Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)
The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation…
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT00778570
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Ottawa Hospital Research Institute
Myopia
Effects of Contact Lens Wear on Children's Self-Perceptions
The purpose of the study is to determine whether contact lens wear will improve children's self-perceptions more than spectacle wear.
- Trial name
- ACHIEVE (NCT00522288)
- Testing
- Soft contact lenses, Spectacle
- Where
- 5 sites in United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE
This prospective observational cohort study will investigate corneal biomechanical characteristics and their relationships with corneal stromal tissue features in adult patients undergoing clinically indicated small-incision…
- Trial name
- SMILE (NCT07906327)
- Testing
- SMILE
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji University
Refractive Error
Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia
This study will be a 12-month, prospective, multicenter, open-label, non-comparative, non-randomized clinical investigation conducted at 8 to 14 sites.
- Trial name
- NCT04075591
- Testing
- iDesign Refractive Studio with STAR S4 IR® Excimer laser System
- Where
- 10 sites in United States
- Volunteers
- 219 people
- Sponsor
- AMO Development, LLC
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