Clinical trials: Refractive Error - Myopia
Refractive Errors
Academic Performance and Refractive Error
Refractive errors constitute the leading cause of visual disability worldwide and that myopia progresses dramatically when students reach school age.
- Trial name
- NCT04338880
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Myopia
Comparison of Next Generation Laser Techniques of Myopia Correction: iDesign vs. SMILE
The proposed study seeks to compare visual acuity, tomographic outcomes, biomechanical changes and inflammatory profile of normal eyes (matched for age, refraction and corneal thickness) undergoing iDesign and SMILE procedure.
- Trial name
- NCT03001401
- Testing
- iDesign, SMILE
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Narayana Nethralaya
Myopia
Clinical Evaluation of Daily Disposable Contact Lenses
The objective of the study is to compare the overall subjective preference of filcon II 3 daily disposable silicone hyrogel contact lenses compared to etafilcon A and nelfilcon A daily disposable conventional hydrogel contact…
- Trial name
- NCT02097030
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision, Inc.
Myopia
Effectiveness of Myopia Control Interventions : A Comparison of Myopia Control in European Children, Adolescents and Young Adults With Defocus Incorporated Multiple Segments (DIMS) and Highly Aspherical Lenslets (HAL) Spectacles, Atropine, Lenses and Combined Treatments
The prevalence of myopia and its complications has risen considerably in recent decades, particularly among children and teenagers.
- Trial name
- NCT07120165
- Testing
- Demographic data collection, Ophthalmological history, Ophthalmological data at each examination
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Myopia, Astigmatism
Clinical Study to Evaluate Effectiveness of Digital Refraction
Prospective, comparative, randomized, non-masked clinical study to compare the a digital refraction with LogMAR VA testing utilizing trial lenses, to standard manual refraction using a Phoropter, and LogMAR VA testing, in…
- Trial name
- NCT03502863
- Testing
- Digital refraction, Manual Refraction
- Where
- 3 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Visibly
Myopia, Dental Caries
Bedtime Routines and Children's Health
In Taiwan, the prevalence of sleep problems, myopia, and dental caries in school-age children is high. Little is known regarding the implementation of oral and vision health outcomes around bedtime.
- Conditions
- Myopia, Dental Caries, Sleep, Asthenopia
- Trial name
- NCT05201924
- Testing
- Bedtime routine, Control
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Myopia, Hyperopia
Daily Wear Corneal Infiltrative Event Study
This DWCIE Study is a prospective cohort study of patients fit to the FDA approved and marketed lotrafilcon A (Ciba Vision, Air Optix Night \& Day Aqua) soft contact lenses for daily wear (DW) with monthly disposal.
- Conditions
- Myopia, Hyperopia, Corneal Infiltrative Events
- Trial name
- DWCIE (NCT00937105)
- Testing
- lotrafilcon A contact lenses, Renu Multiplus, Clear Care
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Myopia, Astigmatism
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
This study evaluates differences in postoperative visual outcomes between patients receiving Topography-Guided LASIK in one eye and Small Incision Lenticule Extraction in the other eye.
- Trial name
- NCT05611294
- Testing
- Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Daily Wear Comparison of Enhanced and Non-Enhanced Silicone Hydrogel Lenses
The purpose of this study is to compare an experimental contact lens with a currently marketed contact lens.
- Trial name
- NCT00813982
- Testing
- Lotrafilcon A Experimental Contact Lens, Lotrafilcon A Commercial Contact Lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Myopia
Comparing Myopia Control Efficacy in Children With 4 Methods: Orthokeratology, DIMS, DISK, and SVS.
The goal of this clinical trial is to learn if 3 optical interventions（DIMS, DISC and orthokeratology) to control myopia have different efficacy to slow myopia progression in children when the control is single focus…
- Trial name
- NCT06654180
- Testing
- Orthokeratology, defocus-incorporated multiple segment lenses (DIMS) spectacles, DISK
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Kaikai QIU
Myopia
Clinical Evaluation of Reusable Soft Contact Lenses
The purpose of this study was to confirm the clinical performance of a novel manufacturing process for comfilcon A contact lenses in habitual wearers over a one-month period of lens wear.
- Trial name
- NCT06119191
- Testing
- Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
- Where
- 5 sites in United States
- Volunteers
- 77 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Orthokeratology
The Effect of Treatment Zone Decentration on Axial Length Elongation After Orthokeratology
Orthokeratology lens is an effective method for myopia control. This study analyzed the effects of treatment zone decentration on axial length elongation in adolescents with orthokeratology lens.
- Trial name
- NCT05365373
- Where
- China
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Visual Fatigue
Discussion on the Effectiveness of Tea on Blood Pressure, Body Composition and Vision Problems in College Students
Background: Tea is a universal beverage and one of the most popular drinks around the world. Some cell and animal experiments have pointed out that drinking tea may be related to hypotension, body composition and vision problems…
- Conditions
- Myopia, Visual Fatigue, Blood Pressure, Body Composition
- Trial name
- NCT06570226
- Testing
- hibiscus tea
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Myopia
Performance Evaluation of Daily Disposable Contact Lenses in Habitual Lens Wearers Who Use Digital Devices Frequently
The goal of this study is to compare the performance of two daily disposable silicone hydrogel lenses.
- Trial name
- NCT05805150
- Testing
- Control Lens (stenfilcon A), Test Lens (senofilcon A)
- Where
- 4 sites in United States
- Volunteers
- 69 people
- Sponsor
- CooperVision, Inc.
Myopia
Myopia Control by Combining Auricular Acupoint and Atropine Eyedrops
This study was designed to compare the difference of using atropine eyedrops alone from atropine combined with the stimulation of auricular acupoints therapy in reducing myopia progression.
- Trial name
- NCT00457717
- Testing
- 0.25 % atropine, 0.5 % atropine, 0.25 % atropine+auricular acupoints
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University, China
Myopia
Preservative-free Topical Anesthetics for Post-PRK Pain
The goal of this interventional comparative study is to assess the efficacy and safety of a novel regimen of preservative-free unit-dose topical anesthetics for controlling early postoperative pain following single-step…
- Trial name
- NCT05733741
- Testing
- Preservative-free Benoxinate hydrochloride 0.4% (Benoxidia unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt), Preservative-free Sodium hyaluronate 0.2% (Polyfresh unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt).
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myopia
The Effects of Low-dose Atropine and Orthokeratology in Pediatric Myopia Control
Both orthokeratology and atropine eye drops are effective methods for myopia control, but few studies have compared them all together simultaneously.
- Trial name
- AVO (NCT05478356)
- Testing
- low-dose atropine eye drops, orthokeratology
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Evidence Based Cataract Study Group
Hyperopia and Myopia
Eye Imaging for the Study of Childhood Myopia
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic.
- Trial name
- SELENA (NCT07335146)
- Testing
- Ophtalmic measurements to estimate geometrical distances, MRI, Ophtalmic measurements to measure wavefront aberrations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Pre-myopia
A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control Spectacles
This study aims to find out whether ZEISS MyoActive lenses can help prevent short-sightedness from developing in children. We aim to recruit at least 50 children in total for this study.
- Trial name
- NCT07779941
- Testing
- Zeiss MyoActive lenses, Single Vision Lenses
- Where
- Singapore
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
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