Clinical trials: Refractive Error - Myopia
Myopia
Evaluating the Initial Lens Handling Experience of Neophyte Contact Lens Wearers Fitted With Precision1 and 1-Day Acuvue Moist Contact Lenses
The initial subjecting handling experience of neophyte contact lens wearers with Precision1 will be compared to that with a daily disposable lens which mas been on the market for numerous years (1-Day ACUVUE Moist).
- Trial name
- SALUKI (NCT04205162)
- Testing
- Verafilcon A, Etafilcon A
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Product Performance of a New Silicone Hydrogel Contact Lens
The objective of this study is to evaluate the product performance of kalifilcon A, compared to the Johnson \& Johnson Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens and Alcon DAILIES TOTAL1®…
- Trial name
- NCT04901897
- Testing
- kalifilcon A, delefilcon A, senofilcon A
- Where
- 35 sites in United States
- Volunteers
- 805 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK
The purpose of this study is to compare LASIK outcomes using the WaveLight ALLEGRETTO WAVE™ wavefront guided or optimized excimer laser treatment with the AMO/VISX CustomVue™ and the LADARVision 4000 excimer laser treatment.
- Trial name
- WLCVLV-001 (NCT00821236)
- Testing
- Excimer Laser, AMO/VISX CustomVue™, LADARVision 4000 excimer laser
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Myopia
Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens
The purpose of this study was to compare subjective ratings of lens handling at insertion for a monthly replacement lens versus a daily disposable lens in habitual soft lens wearers.
- Trial name
- NCT06046209
- Testing
- Control Lens, Test Lens
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Astigmatism, Myopia
Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses
The principal hypothesis is to be tested in this work is that vision stability (the primary outcome measure) with a spherical contact lens correction vs. a toric contact lens correction will be the same.
- Trial name
- NCT04536571
- Testing
- Test Contact lens, Control Contact lens
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Pathological
VEGF Trap-Eye in Choroidal Neovascularization Secondary to Pathologic Myopia (mCNV)
VEGF Trap-Eye will be tested for safety and efficacy in patients with vision loss due to choroidal neovascularization secondary to pathologic myopia. This will be a placebo-controlled trial.
- Trial name
- Myrror (NCT01249664)
- Testing
- VEGF Trap-Eye (BAY86-5321), No Drug
- Where
- 20 sites in Hong Kong, Japan and 3 more
- Volunteers
- 122 people
- Sponsor
- Bayer
Lid Wiper Epitheliopathy
Lid Wiper Epitheliopathy Trial
The purpose of this study is to evaluate the effect of contact lens lubricity on lid wiper epitheliopathy (LWE) in symptomatic contact lens wearers.
- Trial name
- NCT01870856
- Testing
- Spectacles, Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 187 people
- Sponsor
- Alcon Research
Myopia
Investigation of Wearing Compliance of Spectacles for Myopia Control
The goal of this observational study was to compare the wearing patterns of spectacles prescribed for myopia control in juvenile wearers.
- Trial name
- NCT06590441
- Testing
- Myopia control spectacles
- Where
- 4 sites in United Kingdom
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Myopia
Performance of Somofilcon A Over One Week in Wearers Adapted to Omafilcon A
The objective of the study is to determine if habitual or adapted contact lens wearers of Omafilcon A can be confidently refit into Somofilcon A lenses and be successful after one week of daily wear.
- Trial name
- NCT03226353
- Testing
- somofilcon A, omafilcon A
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects
The objective of this study is to evaluate the safety and effectiveness of the Raindrop Near Vision Inlay implanted in bilateral pseudophakes with presbyopia for improvement of near and intermediate vision.
- Trial name
- NCT03017612
- Testing
- Raindrop Near Vision Inlay
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- ReVision Optics, Inc.
Myopia
Lens Fitting Evaluation of CooperVision MyDay™ Compared With 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
Lens Fitting Evaluation of CooperVision MyDay™ Compared with 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
- Trial name
- NCT02341859
- Testing
- stenfilcon A, delefilcon A, narafilcon A
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01309880
- Testing
- Test lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens
Evaluation of the clinical performance of an investigational silicone-hydrogel contact lens (test) compared to a marketed lens (control), when worn on a daily basis for 1 month.
- Trial name
- NCT03499067
- Testing
- Test lens, Control lens
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of Two Daily Disposable Contact Lenses.
The objective of this clinical study is to evaluate the product performance of SofLens daily disposable contact lenses packaged in the investigational Test solution versus SofLens daily disposable contact lenses packaged in…
- Trial name
- NCT01300065
- Testing
- Experimental- Soflens, Marketed - Soflens
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopes implanted in corneal pockets with a delayed or a non-delayed approach.
- Trial name
- NCT03326869
- Testing
- Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Eye Center of North Florida
Myopia, Hyperopia
Accuracy of LASIK Flaps Created With the LenSx® Femtosecond Laser - A Pilot Study
The purpose of this study is to evaluate the thickness accuracy of Laser-assisted in situ keratomileusis (LASIK) flaps created with the LenSx® Laser.
- Trial name
- NCT02575911
- Testing
- Femtosecond Laser System, LASIK surgery
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Alcon Research
Myopia
Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of three silicone hydrogel contact lenses over a 2 week period.
- Trial name
- NCT01244516
- Testing
- galyfilcon A, BC 8.30, lotrafilcon B, BC 8.60, comfilcon A, BC 8.60
- Where
- 35 sites in United States
- Volunteers
- 540 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Refractive Errors, Myopia
Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
The goal of this observational study is to test whether surgeries for lenses designed to be implanted in the eye to correct refractive error can be done without the need for using viscoelastic substances that are used routinely…
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism, Hypermetropia
- Trial name
- NCT06371079
- Testing
- phakic intraocular lens implantation traditional, phakic intraocular lens implantation reduced OVD
- Where
- Iraq
- Volunteers
- 448 people
- Sponsor
- Loay Abdulmutalib Almusawi
Myopia
Comparison of Clinical Performance and Subjective Preference of Three Contact Lenses
The purpose of this study is to evaluate the clinical performance and subject's preference out of three LRE (Limbal Ring Enhancing) lens types: etafilcon A (Johnson\&Johnson), methafilcon A (Interozzo), and methafilcon A…
- Trial name
- NCT03134599
- Testing
- etafilcon A, methafilcon A - Interozzo, methafilcon A - CVI (CooperVision)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.