Clinical trials: Refractive Error - Myopia
Refractive Errors
Bifocal Lenses In Nearsighted Kids
This study will evaluate the use of two different bifocal contact lens add powers to prevent further nearsighted progression in children ages 7 to 11 years old.
- Trial name
- BLINK (NCT02255474)
- Testing
- Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Ohio State University
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
- Trial name
- NCT00708643
- Testing
- Habitual Silicone Hydrogel Contact Lens, narafilcon A
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
Clinical Investigation of the Vision-R800 Device.
Randomized, bilateral, cross-over dispensing study of a standard and VR800 refraction and associated spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT04208750
- Testing
- Vision R-800 Phoropter, Standard Phoropter
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Pete Kollbaum, OD, PhD
Presbyopia
A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients
This study will be a prospective, multicenter clinical trial in which a total of 400 subjects will be enrolled. All subjects will be followed over a 36 month time frame with a maximum of 15 clinical sites participating.
- Trial name
- NCT01373580
- Testing
- The Raindrop Near Vision Inlay
- Where
- 11 sites in United States
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- ReVision Optics, Inc.
Presbyopia, Near Vision
Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia
Phase 3 Efficacy Study to evaluate the Safety and Efficacy of LNZ100 \& LNZ101 for the Treatment of Presbyopia
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- CLARITY 2 (NCT05728944)
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 17 sites in United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia
Daytime Corneal Swelling During Wear of Narafilcon B Lenses
The purpose of this research is to measure daytime open-eye response to wearing of narafilcon B lenses.
- Trial name
- NCT01444287
- Testing
- narafilcon B, Polymacon, Lotrafilcon A
- Where
- Australia
- Volunteers
- 22 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Evaluation of Deposits on Contact Lenses Worn Extended Wear
The purpose of this study was to measure lipid deposits on commercially marketed contact lenses when worn on an extended wear (overnight) basis for 7 days.
- Trial name
- NCT00725530
- Testing
- balafilcon A contact lens (PureVision), etafilcon A contact lens (Acuvue2)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Myopia
Pilot Evaluation of a New Galyfilcon A Contact Lens Compared to a Marketed Galyfilcon A Contact Lens
The purpose of this study is to compare lens surface characteristics and comfort between an experimental contact lens and a marketed contact lens.
- Trial name
- NCT01094730
- Testing
- galyfilcon A prototype lens, marketed galyfilcon A lens
- Where
- 9 sites in United States
- Volunteers
- 185 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses
Bilateral dispensing clinical trial of fanfilcon A toric lens verses enfilcon A toric lens over two weeks.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT02423109
- Testing
- fanfilcon A, enfilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision, Inc.
Myopia
Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia (nearsightedness) is increasing in prevalence throughout the world. It is associated with a risk of potentially blinding complications such as retinal detachment and myopic maculopathy.
- Trial name
- APP (NCT03911271)
- Testing
- 0.1% atropine and 0.01% atropine, 0.01% atropine, 0.9% Sodium-chloride
- Where
- 3 sites in Denmark
- Volunteers
- 97 people
- Sponsor
- Line Kessel
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Refractive Errors
Bifocal & Atropine in Myopia (BAM) Study
This study will test whether the combined treatment of 0.01% atropine and soft bifocal contact lens wear produces slower myopia progression and axial elongation compared to soft bifocal contact lenses alone in children ages 7 to…
- Trial name
- BAM (NCT03312257)
- Testing
- Multifocal D +2.50 add & 0.01% atropine
- Volunteers
- 49 people
- Sponsor
- Jenny Jones
Myopia
A Comparison of Silicone Hydrogel Contact Lenses: AIR OPTIX® COLORS Versus AIR OPTIX® AQUA
The purpose of this study was to compare the overall fit of AIR OPTIX® COLORS to AIR OPTIX® AQUA contact lenses.
- Trial name
- NCT01635920
- Testing
- Lotrafilcon B contact lens with color, Lotrafilcon B contact lens
- Volunteers
- 258 people
- Sponsor
- Alcon Research
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Myopia
Multi-Centre Clinical Evaluation Of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance for handling of two daily disposable contact lenses, stenfilcon A and etafilcon A.
- Trial name
- NCT01707238
- Testing
- etafilcon A, stenfilcon A
- Where
- 7 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Myopia
Silicone Hydrogel Soft Contact Lens 7-Day Extended Wear Basis
The objective of this study is to evaluate the safety and effectiveness of the Bausch + Lomb samfilcon A soft (hydrophilic) contact lens, a new silicone hydrogel contact lens, compared to the Bausch + Lomb PureVision® soft…
- Trial name
- NCT02939950
- Testing
- Bausch + Lomb Samfilcon A Soft Contact Lens, Bausch + Lomb Pure Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Myopia
Clinical Evaluation Of Two Daily Disposable Contact Lenses And A Monthly Replacement Lens
The objective of the study is to compare the clinical performance of silicone hydrogel daily disposable contact lenses, conventional hydrogel daily disposable contact lenses and silicone hydrogel monthly replacement contact…
- Trial name
- NCT01151371
- Testing
- narafilcon B contact lens, nelfilcon A contact lens, lotrafilcon B contact lens
- Where
- 28 sites in United States
- Volunteers
- 452 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Evaluation of Stenfilcon A Contact Lenses
This study is to evaluate the fitting performance of stenfilcon A contact lens (test) compared to narafilcon A contact lens (control).
- Trial name
- NCT03471832
- Testing
- stenfilcon A lens, narafilcon A lens
- Where
- 4 sites in Japan
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Performance of Existing Wearers of Avaira Sphere Following a Refit With Clariti Elite Sphere
The aim of this dispensing study is to evaluate the clinical performance of existing wearers of Avaira sphere lenses following a refit with Clariti Elite sphere over 4 weeks of daily wear.
- Trial name
- NCT02248727
- Testing
- somofilcon A
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.