Clinical trials: Refractive Error Correction
Presbyopia
Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for Correction of Presbyopia.
This clinical investigation is a prospective, multicentre, non-comparative case series to assess safety and efficacy of CorVision® bioengineered corneal inlay for improving uncorrected near vision in presbyopic subjects.
- Trial name
- CorVision (NCT04465409)
- Testing
- Intrastromal implantation of CorVision bioengineered corneal inlay for correction of presbyopia.
- Where
- Czechia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- LinkoCare Life Sciences AB
Astigmatism
Nomogram for Astigmatism Correction of KLEx
The goal of this clinical trial is to learn if nomogram could promote treatment outcomes in astigmatism correction. The main question it aims to answer is: does the nomogram could promote treatment outcomes in astigmatism…
- Trial name
- NCT07605221
- Testing
- nomogram
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tianjin Eye Hospital
Error, Refractive
Errors of Refraction Among Primary School Children
This study will include primary school children to evalute their refraction and follow those who will wear glasses to detect their compliance.
- Trial name
- NCT05366543
- Testing
- Visual acuity measurement
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of MSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "MSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716385
- Testing
- MSiHy Silicone Hydrogel Soft Contact Lens, Monthly Silicone Hydrogel Contact Lenses (oA)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Myopia
Aberration-Free Refraction Correction
In the interest of improving visual quality after LASIK we have designed a multifaceted study to test the theoretical, physical, biomechanical and functional effects of commercial and independently designed aspherical ablation…
- Trial name
- NCT00172913
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hyperopia and Myopia
Evaluation of a New Laser Refractive Vision Correction Using the TENEO™ 317 Model 2
Prospective, post market clinical follow up study with a three months postoperative follow up to evaluate the visual and refractive outcomes of OCTAVIUS treatment when used as intended.
- Trial name
- NCT06997003
- Testing
- Anterior treatment mode, Total treatment mode
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- Bausch & Lomb GmbH
Glaucoma, Cataract Senile
Effect of Presbyopic Correction Lens on Humphrey Visual Field Testing in Patients With Multifocal Intraocular Lens
Purpose of this study was to evaluate the effect of presbyopic correction lens on Humphrey visual field (HVF) testing in patients with 2 models of multifocal intraocular lens (MIOL) both with and without glaucoma.
- Trial name
- NCT05220007
- Testing
- Humphrey visual field testing
- Where
- Thailand
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser on an Implanted Intraocular Lens
This is a prospective non-randomized patient controlled single center study which is designed to evaluate the clinical outcomes of the treatment of an implanted intraocular lens using a low-energy femtosecond laser for refractive…
- Trial name
- NCT07473557
- Testing
- Device
- Where
- Panama
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Myopia
Comparative Study of SMILE, ICL, and Wavelight Plus Alcon Technologies in Myopia Correction
Myopia is a prevalent refractive error with significant lifestyle impact. While traditional SMILE (Small Incision Lenticule Extraction) and ICL (Implantable Collamer Lens) surgeries are standard options, the advent of the…
- Trial name
- NCT06788418
- Testing
- Wavelight Plus Alcon system, SMILE, ICL
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Visionly Plus Eye Hospital
Hyperopia, Long Sight
Zimbabwe Eyecare And Learning(ZEAL):Formative Research on Hyperopia and Educational Outcomes in Primary School Children
The purpose of this study is to determine whether uncorrected or corrected long-sightedness (hyperopia) has an impact on reading skills, in Grade 2 or Grade 4 school-aged children from Mashonaland Central province of Zimbabwe…
- Trial name
- ZEAL (NCT05538182)
- Testing
- Spectacles
- Where
- Zimbabwe
- Volunteers
- 1,883 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Presbyopia
PROductivity Study of Presbyopia Elimination in Rural-dwellers II
The investigators will conduct a randomized-controlled trial. The participants will be textile workers aged 35 years and above with uncorrected presbyopia who are employed by a single Indian garment manufacturer - employed by…
- Trial name
- PROSPERII (NCT04629820)
- Testing
- Spectacles
- Where
- India
- Volunteers
- 682 people
- Sponsor
- Queen's University, Belfast
Hyperopia, Farsightedness
Correction of Farsightedness in Children Study
The Correction of Hyperopia In Children Study (CHICS) is a placebo-controlled, randomized, masked investigation of the effect of spectacle correction for moderate amounts of hyperopia on visual function, attention, and reading…
- Trial name
- CHICS (NCT00472212)
- Testing
- Spectacles, Control
- Where
- 4 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Presbyopia
Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs
Primary objective of this study is to introduce a modified luminous efficiency function that addresses the distinct total eye light transmittance of patients who underwent pseudophakic presbyopic correction with extended-depth of…
- Trial name
- V(λ)'_EDOF (NCT07077967)
- Testing
- Phacoemulsification with EDOF IOLs
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia
Efficacy and Safety of ReLEx Smile for Laser Correction of Myopia
Evaluation of the safety and efficacy of the Carl Zeiss Meditec VisuMax femtosecond laser for lamellar resection (ReLEx smile) in the reduction of myopia.
- Trial name
- NCT01481792
- Where
- Denmark
- Volunteers
- 125 people
- Sponsor
- University of Aarhus
Astigmatism
Evaluation Study on Corneal Lens for Vision Correction
The objective of this study is to evaluate the fitting and visual outcomes of Nexis Lens, made of silicone commonly used in the contact lens industry, on healthy eye with or without astigmatism.
- Trial name
- NCT02053688
- Testing
- Astigmatic Correction Lens (Nexis ACCL lenses), Toric Soft Contact Lenses
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Presbyopia
PROductivity Study of Presbyopia Elimination in Rural-dwellers III
The investigators will conduct an embedded mixed methods study in which the primary approach is a randomized controlled trial (RCT), and the secondary or embedded approach is a descriptive qualitative study.
- Trial name
- PROSPERIII (NCT04654013)
- Testing
- Spectacles
- Where
- India
- Volunteers
- 1,291 people
- Sponsor
- Queen's University, Belfast
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of DSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "DSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716372
- Testing
- DSiHy Silicone Hydrogel Soft Contact Lens, Daily Silicone Hydrogel Contact Lenses (oB)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Myopia
Comparison of Next Generation Laser Techniques of Myopia Correction: iDesign vs. SMILE
The proposed study seeks to compare visual acuity, tomographic outcomes, biomechanical changes and inflammatory profile of normal eyes (matched for age, refraction and corneal thickness) undergoing iDesign and SMILE procedure.
- Trial name
- NCT03001401
- Testing
- iDesign, SMILE
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Narayana Nethralaya
Hyperopia
Safety and Effectiveness Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Hyperopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of hyperopia, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762281
- Testing
- MEL 80 Hyperopic LASIK Treatment
- Where
- 6 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Presbyopia, Myopia
Presbyopic Phakic Intraocular Lens for Myopia Correction
This is a prospective single-center study of implantations of the presbyopic version of phakic intraocular lens IPCL (EyeolUK, United Kingdom).
- Trial name
- NCT03836898
- Testing
- Presbyopic posterior chamber phakic intraocular lens IPCL
- Where
- Czechia
- Volunteers
- 10 people
- Sponsor
- Gemini Eye Clinic