Clinical trials: Refractive Error Correction, open to volunteers
Presbyopia Correction, Presbyopia
Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match
The purpose of the study is to evaluate the binocular clinical endpoints of distance, intermediate, and near vision and patient reported outcomes utilizing mini-monovision versus mix-match approaches for the correction of…
- Conditions
- Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
- Trial name
- NCT07860567
- Testing
- TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Dr. Daniel H. Chang, MD
Myopia
Pilot Study on the Adaptation and Tolerance of Essilor® Myopia-control Spectacle Lenses
This observational pilot study aims to evaluate the adaptation and tolerance of Essilor® Stellest® myopia-control spectacle lenses in children with progressive myopia.
- Trial name
- STELLAR (NCT07340931)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Myopia, High Myopia
Clinical Results of Small Incision Lenticule Extraction (SMILE) for the Correction of High Myopia
Small Incision Lenticule Extraction (SMILE) was introduced in 2011 using the VISUMAX femtosecond laser (Carl Zeiss Meditec, Jena, Germany). It is designed for correction of myopia and myopic astigmatism.
- Trial name
- NCT04110067
- Testing
- Small Incision Lenticule Extraction (SMILE) with Visumax (Carl Zeiss Meditec, Jena)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Suphi Taneri
Myopia
Comparison of Femto LDV Z8 Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) and Visumax Small Incision Lenticule Extraction (SMILE)
This observational study aims to compare two laser corrective procedures for treating myopia and myopic astigmatism: a novel refractive technique, the CLEAR procedure, and the established SMILE procedure.
- Trial name
- NCT06774651
- Testing
- Procedure: Corneal lenticule extraction for advanced refractive correction (CLEAR), Procedure: Small Incision Lenticule Extraction (SMILE)
- Where
- Singapore
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Singapore Eye Research Institute
Astigmatism
Nomogram for Astigmatism Correction of KLEx
The goal of this clinical trial is to learn if nomogram could promote treatment outcomes in astigmatism correction. The main question it aims to answer is: does the nomogram could promote treatment outcomes in astigmatism…
- Trial name
- NCT07605221
- Testing
- nomogram
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tianjin Eye Hospital
Myopia
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
- Trial name
- NCT06305663
- Testing
- Bausch + Lomb (kalifilcon A) Myopia Control Soft (Hydrophilic), CooperVision MiSight (omafilcon A/60%) Myopia Control one day Soft Contact Lens
- Where
- 11 sites in China
- Volunteers
- 418 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Comparative Study of SMILE, ICL, and Wavelight Plus Alcon Technologies in Myopia Correction
Myopia is a prevalent refractive error with significant lifestyle impact. While traditional SMILE (Small Incision Lenticule Extraction) and ICL (Implantable Collamer Lens) surgeries are standard options, the advent of the…
- Trial name
- NCT06788418
- Testing
- Wavelight Plus Alcon system, SMILE, ICL
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Visionly Plus Eye Hospital
Presbyopia Correction, Astigmatism
A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery
To evaluate the clinical outcomes and patient satisfaction of two commercially available trifocal toric intraocular lenses Primary Objective: To compare the distance-corrected intermediate visual acuity between the two trifocal…
- Conditions
- Presbyopia Correction, Astigmatism, Cataract
- Trial name
- NCT07232615
- Testing
- Optiflex TRIO Intraocular Lens, AcrySof® IQ PanOptix®
- Where
- 6 sites in Germany, India and 1 more
- Volunteers
- 138 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Myopia
Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia
This study aims to perform biomechanical tests on extracted CLEAR lenticles that are routinely discarded after surgery. The investigators also aim to perform Brillouin microscopy to get an in-vivo assessment of the patient's…
- Trial name
- CLEAR Biomech (NCT04817592)
- Testing
- Corneal lenticule extraction for advanced refractive correction (CLEAR)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bern
Presbyopia
Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs
Primary objective of this study is to introduce a modified luminous efficiency function that addresses the distinct total eye light transmittance of patients who underwent pseudophakic presbyopic correction with extended-depth of…
- Trial name
- V(λ)'_EDOF (NCT07077967)
- Testing
- Phacoemulsification with EDOF IOLs
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Pterygium, Corneal Astigmatism
Comparison Of Keratometric Readings Pre and Post Pterygium Excision With Conjunctival Autograft Transplantation
Pterygium, often called "surfer's eye," is a common eye condition in which a raised, fleshy growth of tissue extends from the white part of the eye onto the clear cornea.
- Trial name
- NCT07198126
- Testing
- Pterygium Excision with Conjunctival Autograft
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Mughal Eye Trust Hospital
Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness)
Effect of Presbyopia Correction on Livelihood and Repayment Among Solar Customers in Western Region, Kenya
With age, people lose the ability to see things that are near them clearly. This is known as presbyopia. Although this is a normal ageing process, it can be corrected with near vision eyeglasses - colloquially known as reading…
- Conditions
- Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness), Repayment Behaviour, Livelihoods
- Trial name
- NCT06774183
- Testing
- Near vision glasses for presbyopia correction
- Volunteers
- 1,085 people
- Sponsor
- Dot Glasses Kenya
Presbyopia
Phase III Presbyopia Correction Using the VIS Opti-K™ System
The goal of this clinical trial is to evaluate the safety and efficacy of using the VIS Opti-K System to enable monovision by providing temporary improvement in near vision through the treatment of the non-dominant eye of low…
- Trial name
- Opti-K™ (NCT06487897)
- Testing
- Optimal laser keratoplasty
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- VIS, Inc.
Presbyopia
Quantitative Refractive Crosslinking in Presbyopia Aged Patients
An 'on-eye' UV delivery system for corneal crosslinking can be used safely and effectively to help free presbyopic patients from the need for reading glasses.
- Trial name
- NCT07137767
- Testing
- Quantitative refractive crosslinking
- Where
- 2 sites in Brazil, Dominican Republic
- Volunteers
- 25 people
- Sponsor
- TECLens, Inc.
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Hyperopia and Myopia
Evaluation of a New Laser Refractive Vision Correction Using the TENEO™ 317 Model 2
Prospective, post market clinical follow up study with a three months postoperative follow up to evaluate the visual and refractive outcomes of OCTAVIUS treatment when used as intended.
- Trial name
- NCT06997003
- Testing
- Anterior treatment mode, Total treatment mode
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- Bausch & Lomb GmbH
Astigmatism
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
This study aims to evaluate the safety and effectiveness of femtosecond laser arcuate corneal relaxing incisions (AK) combined with Light Adjustable Lens (LAL) implantation for correcting pre-existing corneal astigmatism in…
- Trial name
- NCT07140653
- Testing
- Femto arcs, Light Adjustable Lens (LAL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Center For Sight
Myopia, Refractive Ametropia
Comparison of Two Rotational Alignment Methods for Astigmatism Correction in SMILE Surgery
Small incision lenticule extraction (SMILE) is a commonly used corneal refractive procedure for correcting myopia and myopic astigmatism.
- Trial name
- NCT07696468
- Testing
- Device-assisted cyclotorsion control during SMILE, Manual limbal marking-guided cyclotorsion adjustment during SMILE
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Presbyopia
Open Label, Multi-center, Phase I Study of TECLens Quantitative Refractive Crosslinking in Presbyopia-Aged Patients.
An 'on-eye' UV delivery system for corneal crosslinking can be used safely and effectively to help free presbyopic patients from the need for reading glasses.
- Trial name
- NCT07208604
- Testing
- Quantitative refractive crosslinking
- Where
- Philippines
- Volunteers
- 25 people
- Sponsor
- TECLens, Inc.
Refractive Error Correction, Visual Acuity
Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome
This study seeks to determine whether glasses prescriptions determined from computer analysis of detailed images of the eyes provide better vision outcomes for children with Down syndrome than prescriptions determined using…
- Trial name
- NCT07490444
- Testing
- Metric-optimized spectacles, Routine Clinical Spectacles
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University