Clinical trials: Regional Pain Syndrome
Pain, Joint, Complex Regional Pain Syndromes
Pulsed Electromagnetic Fields (PEMFS) in Complex Regional Pain Syndrome Type i (CRPS-I) of the Foot (PeCFoA)
The investigators hypothesize that the association of I-ONE® therapy with standard rehabilitation treatment can optimize the clinical and functional recovery of patients with pulsed electromagnetic fields (PEMFs) (I-ONE® therapy)…
- Conditions
- Pain, Joint, Complex Regional Pain Syndromes, Ankle Disease, Foot Diseases
- Trial name
- (PeCFoA) (NCT05922618)
- Testing
- I-One
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Complex Regional Pain Syndrome
Evaluation of the Physiodoloris Pain Monitor in Patients With Complex Regional Pain Syndrome
A French University team (M. Jeanne, MD, and M. LOGIER, Ph D) have developed a pain assessment tool based on the analysis of the variability heart rate which evaluates the Analgesia Nociception Index (ANI).
- Trial name
- ANI-ALGO (NCT02663284)
- Testing
- Ropivacaine 0.5%
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hopital Foch
Failed Back Surgery Syndrome, Limb Ischemia
Evaluation of Online Tool (E-TOOL SCS) in Spinal Cord Stimulaion
This observational multicenter study aims to evaluate the reliability and validity of the e-tool for selecting patients eligible for SCS for chronic pain caused by one of the four etiologies listed above in the experience of…
- Conditions
- Failed Back Surgery Syndrome, Limb Ischemia, Neuropathic Pain, Complex Regional Pain Syndromes
- Trial name
- E-TOOLSCS (NCT06229015)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
CRPS (Complex Regional Pain Syndrome) Type I
Ultrasound and Somatosensory Median Nerve Evaluation in CRPS I
Complex regional pain syndrome (CRPS) is a disorder falling within the sphere of neuropathic pain, characterised by a plethora of symptoms.
- Trial name
- MEDICUS (NCT06978608)
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb
Embodied Virtual Reality for Chronic Pain
Virtual reality creates interactive, multimodal sensory stimuli that have demonstrated considerable success in reducing pain. Much research so far has focused on VR's ability to shift patients' attention away from pain; however…
- Conditions
- Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb, Complex Regional Pain Syndrome I (CRPS I), Complex Regional Pain Syndrome I of Upper Limb
- Trial name
- NCT05160038
- Testing
- Embodied virtual reality
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University of Zurich
Complex Regional Pain Syndrome Type I
Phase 3, Open-Label Extension Study of AMBTX-01 (Neridronate) for Complex Regional Pain Syndrome Type 1
A Phase 3 open-label extension study of AMBTX-01 (neridronate) for Complex Regional Pain Syndrome Type 1
- Trial name
- NCT07857733
- Testing
- Neridronate
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Ambros Therapeutics, Inc.
Pain Syndrome, Analgesia
Erector Spinae Plane Block Versus Paravertebral Block for Analgesia After Cardiac Surgery (PEPS)
The purpose of this randomized double-blind study is to compare the analgesic efficacy of the bilateral Erector Spinae Plane (ESP) block versus the bilateral Thoracic Paravertebral block (TPVB), by ultrasound-guided single…
- Conditions
- Pain Syndrome, Analgesia, Anesthesia, Local
- Trial name
- PEPS (NCT04546113)
- Testing
- Ultrasound-guided Bilateral Paravertebral Block performed with a 20 ml injection of Ropivacaine 3,75 mg/ml/side, Ultrasound-guided Bilateral Erector Spinae plane Block performed with a 20 ml injection ropivacaine 3,75 mg/ml/side
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Institut Mutualiste Montsouris
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle: Phase II
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05459324
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Albany Medical College
Myofascial Pain of Upper Trapezius Muscle
Comparison of the Effectiveness of Dry Needling Versus the Combination of Dry Needling and Local Anesthetic Injection in Myofascial Pain Syndrome of the Upper Trapezius Muscle: A Sham-Controlled, Randomized Clinical Trial
This study was designed to compare the effectiveness of three different treatment protocols in patients diagnosed with myofascial pain syndrome of the upper trapezius muscle.
- Trial name
- NCT07456735
- Testing
- Dry Needling, Local Anesthehetic Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Emre Ata, Assoc Prof
Complex Regional Pain Syndrome
Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS
Complex Regional Pain Syndrome is a debilitating and extremely difficult to treat condition. There is a large body of evidence demonstrating the therapeutic value of N-methyl-D-aspartate (NMDA)-receptor antagonists in CRPS.
- Trial name
- NCT00579085
- Testing
- Ketamine, IV NSS, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Drexel University College of Medicine
Complex Regional Pain Syndrome, Type I
Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I
This clinical trial is being conducted to demonstrate the efficacy of neridronic acid in the treatment of pain associated with complex regional pain syndrome type I (CRPS-I).
- Trial name
- NCT02402530
- Testing
- Neridronic acid 62.5 mg
- Where
- 59 sites in United States, Germany and 1 more
- Volunteers
- 459 people
- Sponsor
- Grünenthal GmbH
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Complex Regional Pain Syndromes
TMS for Complex Regional Pain Syndrome
The aim of the current study is to assess the efficacy of TMS in the treatment of Complex Regional Pain Syndrome (CRPS). It is hypothesized that participants who receive TMS (Group 1) relative to sham treatment (Group 2) once…
- Trial name
- NCT03137472
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Reflex Sympathetic Dystrophy, Causalgia
Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror Therapy
AlgoMIR project born thanks to a meeting between pain professionals and re-education staff. The goal of this project is to develop and evaluate a program of learning with exercises by mirror therapy, that could be easily shared…
- Trial name
- AlgoMIR (NCT02667717)
- Testing
- Mirror therapy, Usual care
- Where
- 5 sites in France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Complex Regional Pain Syndrome Type I
Complex Regional Pain Syndrome in Children: Impact of Bergès Relaxation on the Autonomic Balance
Complex regional pain syndrome (CRPS) is a disease provoking chronic pain in the limbs, following a trauma. Patient care is complicated by the variable clinical picture and response to treatment.
- Trial name
- NCT03309774
- Testing
- questionnaires, holter electrocardiogram, blood pressure
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Arthritis, Arthritis, Degenerative
Clinical Evaluation of the TITAN™ Total Shoulder System
A post market, non-randomized, multi-center, open-label,clinical study using survivorship to study the safety and efficacy of the Integra® TITAN™ Total Shoulder System 1.0 (TAS) when used for total shoulder arthroplasty.
- Conditions
- Arthritis, Arthritis, Degenerative, Rheumatoid Arthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region
- Trial name
- NCT03245320
- Testing
- Integra TITAN™ Total Shoulder Generation 1.0
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Smith & Nephew, Inc.
Complex Regional Pain Syndromes
The Use of Zoledronic Acid to Complex Regional Pain Syndrome
To evaluate the efficacy and the safety of using a single, intravenous 5mg dose of zoledronic acid in managing pain in Complex Regional Pain Syndrome patients.
- Trial name
- Aclasta (NCT01788176)
- Testing
- Zoledronic acid
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital