Clinical trials: Regional Pain Syndrome
Complex Regional Pain Syndrome Type I
Pain in Complex Regional Pain Syndrome
CRPS is a complex pain condition that usually develops in response to trauma and immobilization which is very painful and debilitating.
- Trial name
- NCT04667364
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Complex Regional Pain Syndrome (CRPS) TYPE I
Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
Vitamin C with its antioxidant role has many indications. The objective of this study is to demonstrate that taking vitamin C as a preventive significantly reduces the occurrence of complex regional pain syndrome (CRPS) type 1 in…
- Trial name
- SDRC (NCT02390505)
- Testing
- Vitamin C
- Where
- 3 sites in France
- Volunteers
- 995 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Complex Regional Pain Syndrome (CRPS)
Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients
Pain avoidance helps with survival. However, chronic pain patients often avoid valued life activities fearing onset or exacerbation of pain. Hence, pain avoidance no longer protects, but reduces quality of life.
- Trial name
- NCT07791966
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
CRPS I, Causalgia
Trialing of ISS in Patients With CRPS
This is a multi-center, prospective, open-label, single-arm, observational, feasibility study. The goal of this study is to determine the feasibility of intra-spinal stimulation with optimal paresthesia coverage therapy for…
- Trial name
- NCT03954080
- Testing
- Intraspinal-optimal stim therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Millennium Pain Center
Complex Regional Pain Syndrome Type I of the Upper Limb
Effects of Repetitive Electric Sensory Stimulation (RSS) as Intervention in Complex-regional-pain-syndrome Type I (CRPS)
The purpose of this study is to test a specific nerve stimulation protocol as therapeutic option in patients diagnosed with CRPS (complex regional pain syndrome) of the upper extremity.
- Trial name
- NCT01915329
- Testing
- RSS (repetitive sensory stimulation)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Complex Regional Pain Syndrome I of Upper Limb
RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb
This is a double-blind randomized controlled trial to evaluate the efficacy of the sympathetic block via thoracic vertebra T3 for the treatment of CRPS I upper limb.
- Trial name
- NCT01612364
- Testing
- thoracic sympathetic block
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Chronic Pain
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
This observational study will collect prospectively specified data on patient characteristics and clinically relevant outcomes in patients who receive a ketamine infusion at Stanford Pain Management Center for the treatment of…
- Trial name
- NCT05477004
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Theresa Lii
Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS)
Two Point Discrimination
SPECIFIC AIMS Pain in both youth and adults is a complex, subjective and personal experience, and remains poorly understood. One particularly perplexing dimension of some forms of pain is the tendency of pain to spread outside of…
- Conditions
- Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS), Amplified Musculoskeletal Pain Syndrome (AMPS), Low Back Pain
- Trial name
- TPD (NCT03686748)
- Testing
- Two-point discrimination training, One-point discrimination training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stroke, Complex Regional Pain Syndrome I (CRPS I)
Mirror Therapy for Complex Regional Pain Syndrome in Stroke Patients
The goal of this clinical study is to evaluate the effectiveness of mirror therapy in treating complex regional pain syndrome (CRPS) in patients after stroke using clinical assessments, electrophysiological evaluations, and…
- Conditions
- Stroke, Complex Regional Pain Syndrome I (CRPS I), Mirror Therapy
- Trial name
- MT-CRPS-ST (NCT07537465)
- Testing
- Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Complex Regional Pain Syndrome Type I
Clinical Evaluation of the Effects of Mirror Therapy in Patients With Complex Regional Pain Syndrome (CRPS) Type 1
CRPS Type 1 can occur after traumas, surgical applications or central nervous system disorders. The triggering factor in CRPS type 1 is fracture in about half of the cases.
- Trial name
- NCT03377504
- Testing
- mirror therapy, Routine physical therapy and exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ankara University
Complex Regional Pain Syndromes
Role of the Gut Microbiome in Complex Regional Pain Syndrome
The objective of this prospective, observational study is to determine the association between the composition of the gut microbiota and the severity and persistence of Complex Regional Pain Syndrome symptoms (Study A).
- Trial name
- NCT03612193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Complex Regional Pain Syndromes
Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation
The goal of this clinical trial is to learn about cognitive changes during rehabilitation in CRPS patients. The main questions it aims to answer are: What are the cognitive changes in CRPS? Do cognitive functions change during…
- Trial name
- NCT05696587
- Testing
- Multimodal rehabilitation
- Where
- Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Acute Pain, Atrophic
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy.
- Conditions
- Acute Pain, Atrophic, Goals, Impairment
- Trial name
- NCT02971072
- Testing
- Subacromial injection, Physical Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oregon
CRPS Type I of the Upper Extremity, Neuropathy of the Median Nerve
Two Measures of Tactile Acuity in CRPS Type I Patients
This study aims to investigate whether two different measures of tactile acuity lead to comparable results in patients diagnosed with CRPS Type I of the upper extremity.
- Conditions
- CRPS Type I of the Upper Extremity, Neuropathy of the Median Nerve, Healthy Controls
- Trial name
- NCT01888783
- Testing
- Tactile acuity measured by 2PD and the GOT
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Carpal Tunnel Syndrome
Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery
This study is focused on comparing patients' pain scores on a visual analogue scale (VAS) and the difference in analgesics use post-operatively (with the same prescription defining only the maximum frequency) between lidocaine…
- Trial name
- NCT02315573
- Testing
- Wrist block anesthesia
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Pain Syndrome, Fibromyalgia
Neuro-modulation of Central Pain Pathways in Non Inflammatory Musculoskeletal Pain Syndrome
The aim of this clinical trial is to see if transcranial electrical stimulation (tES) can help reduce pain and improve quality of life in children and adolescents (ages 10-21, both sexes) with juvenile fibromyalgia or other…
- Conditions
- Pain Syndrome, Fibromyalgia, CRPS (Complex Regional Pain Syndromes), Neuromodulation
- Trial name
- NMJFP protocol (NCT07785362)
- Testing
- Neuro-modulation of central pain pathways in non inflammatory musculoskeletal pain syndrome (NMJFP)
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Istituto Giannina Gaslini
Chronic Pain Syndrome, Peripheral Neuropathic Pain
Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning
Background: Chronic neuropathic pain associated with peripheral neuropathies cannot be attributed solely to lesions of peripheral sensory axons and likely involves alteration in the processing of nociceptive information in the…
- Trial name
- SMR-Pain (NCT06234917)
- Testing
- EEG-based neurofeedback for brain activity modulation
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy)
Complex Regional Pain Syndromes
Thoracic Paraspinal Soft Tissue Mobilizations in Treatment of Patients With Upper Limb Complex Regional Pain Syndrome
This study examines the prevalence of trigger points in muscles in the thorax in upper limb Complex Regional Pain Syndrome (CRPS) patients, compared to healthy subjects.
- Trial name
- NCT03111225
- Testing
- massage
- Where
- Israel
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Reuth Rehabilitation Hospital
Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture
Prism Adaptation Therapy for CRPS Type 1
Complex Regional Pain Syndrome (CRPS) is a clinical condition characterized by pain that arises either without an identifiable triggering factor or with a severity disproportionate to the initiating event.
- Conditions
- Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture, CRPS (Complex Regional Pain Syndromes), Neuropathic Pain
- Trial name
- NCT07370012
- Testing
- The Prism Adaptation Therapy Group, The Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara Etlik City Hospital