Clinical trials: Regulation, Self
ADHD
Amiloride Hydrochloride as an Effective Treatment for ADHD
The investigators are proposing to test a medication derived from our prior studies of the gene SLC9A9. This one gene makes NHE proteins that control how we learn and remember items, which is impaired in ADHD and may cause an…
- Trial name
- NCT01733680
- Testing
- amiloride, Behavioral
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- State University of New York - Upstate Medical University
Depression, Obesity
Research Aimed at Improving Both Mood and Weight
The RAINBOW study is an NIH R01-funded randomized controlled trial to evaluate the clinical and cost effectiveness and implementation potential of a primary care integrated multicondition intervention program to help improve mood…
- Trial name
- RAINBOW-ENGAGE (NCT02246413)
- Testing
- RAINBOW Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 409 people
- Sponsor
- Palo Alto Medical Foundation
Obesity
Enhancing Self Regulation as a Strategy for Obesity Prevention in Head Start Preschoolers
The goal of this integrated project targeting the Childhood Obesity Prevention Challenge Area is to reduce the prevalence of obesity among children attending Head Start in Michigan.
- Trial name
- NCT01398358
- Testing
- Parents of Preschoolers Series, Incredible Years Series
- Where
- United States
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking, Binge Eating
Applying Novel Technologies and Methods to Self-Regulation: Behavior Change Tools for Smoking and Binge Eating
This study will evaluate the extent to which we can engage and manipulate putative targets within the self-regulation domain within and outside of laboratory settings in samples of smokers and overweight/obese individuals with…
- Conditions
- Smoking, Binge Eating, Behavior
- Trial name
- NCT03687658
- Testing
- Laddr
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetes Mellitus, Type 2, Overweight and Obesity
Adaptation of a Digital Weight Loss Intervention Promoting Self-regulation for Use in Type 2 Diabetes
The purpose of this study is to 1) adapt a weight loss app that the Tate team has previously developed to promote PA and diet and adapt them to the needs and perspectives of those with Type 2 Diabetes (T2DM), integrate daily…
- Trial name
- NCT03650088
- Testing
- Behavioral weight loss with digital tools
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Reducing Challenging Behaviors in Children With Autism Through Digital Health
School-based behavioral approaches to managing challenging behaviors in children with ASD are limited by three key factors: 1) children with ASD often have difficulties communicating their emotions; 2) it is challenging to…
- Trial name
- NCT05277194
- Testing
- KeepCalm app
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Chronic Low Back Pain
Physical Activity Interventions To Heal Chronic Low Back Pain
This study will advance understanding on the mechanisms that mediate improved outcomes for chronic low back pain and provide specific directions for optimizing physical activity interventions for this population.
- Trial name
- PATH (NCT04678297)
- Testing
- Physical activity + emotion regulation intervention, Physical activity control intervention
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of Connecticut
Mental Health Issue, Emotional Stress
DISCOVER Workshop Programme for Care Experienced Young People
The NHS DISCOVER team has secured 2-year funding from the Maudsley Charity to tailor the workshop programme the investigators deliver in school Sixth Forms to meet the specific needs of Care Experienced young people.
- Conditions
- Mental Health Issue, Emotional Stress, Emotional Regulation
- Trial name
- NCT05220436
- Testing
- DISCOVER workshop programme
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- South London and Maudsley NHS Foundation Trust
Self-regulation, Binge Eating
Using Mobile Technology to Improve Self-Regulation
This study will evaluate the degree to which engaging targets produces a desired change in medical regimen adherence (across 4-week interventions) and health behavior among smokers (n=50) and overweight/obese persons with binge…
- Conditions
- Self-regulation, Binge Eating, Smoking
- Trial name
- NCT03774433
- Testing
- Laddr
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Type 1 Diabetes
Technology-delivered Physical Activity Program for Adolescents With Type 1 Diabetes
This project is comprised of a two-arm randomized control trial (RCT) testing the feasibility, acceptability, and preliminary efficacy of a nationally scalable program, Activate, a 12-week, technology-delivered diabetes…
- Trial name
- Activate (NCT05319600)
- Testing
- Diabetes behavior change skills training, Physical activity promotion program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
Major Depressive Disorder, Suicidal Ideation
Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation
The study aims to use a combined clinical and translational approach to identify an efficient pharmacotherapy for the acute management of suicidality and the epigenetic regulation associated with the treatment.The primary…
- Trial name
- AFSP (NCT01134731)
- Testing
- paliperidone, lithium
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Alabama at Birmingham
Myocardial Ischemia
Pressure Guidewire System Multi-center, Prospective, Self-Control, Clinical Trial
Patients with intermediate-grade coronary stenosis undergo measurement of fractional flow reserve using the test article (Zurich Pressure Guidewire System) and predicate article (Abbott PressureWire System).
- Trial name
- NCT04582877
- Testing
- FFR measurement
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zurich Medical Inc.
Parenting, Substance Abuse Relapse
Integration of DBT Skills and Parent Training for Parents With a History of Substance Use
This treatment development study is aimed at developing and pilot testing a 20-week remotely delivered group intervention that integrates two evidence-based treatments: 1) Dialectical Behavior Therapy (DBT) Skills - targeting…
- Conditions
- Parenting, Substance Abuse Relapse, Emotional Regulation
- Trial name
- NCT05287178
- Testing
- DBT Skills + Parent Training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Obesity
Promoting The Self-Regulation Of Energy Intake
The goal of this study is to develop and test the efficacy of a scientifically-based, culturally competent seven-session parent directed, obesity prevention program focused on parental feeding strategies that support young…
- Trial name
- SEEDs (NCT01513343)
- Testing
- Parent and child groups focused on self-regulation of eating
- Where
- 2 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Parenting, Parent-Child Relations
Middle School Success Over Stress
It is clear that the COVID-19 pandemic has impacted families adversely in multiple ways, including economic stressors, mental health-related functioning, social/familial functioning, as well as responses to mandated safety…
- Conditions
- Parenting, Parent-Child Relations, Depression, Self-regulation
- Trial name
- MSSOS (NCT05117099)
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Aggression, Anger
Hostile Bias Modification Training Online Study II
The purpose of this study is to see how people respond on a word completion task relates to how they behave and respond to situations in the real world. This is a two part research study.
- Conditions
- Aggression, Anger, Emotion Regulation, Self-Control
- Trial name
- HBMT II (NCT04015440)
- Testing
- HBMT, Other Training
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Suicidal Ideation, Suicide, Attempted
Establishing Efficacy of an Inpatient Intervention and Phone App to Reduce Suicidal Risk
In this 2-site study, University of Texas Southwestern Medical Center (UTSW) and Western Psychiatric Institute and Clinic (WPIC), the investigators will conduct a randomized clinical trial (RCT) in 240 psychiatrically…
- Trial name
- ASAP+BRITE (NCT03825588)
- Testing
- ASAP (As Safe As Possible), BRITE smart phone app, TAU (treatment as usual)
- Where
- 2 sites in United States
- Volunteers
- 241 people
- Sponsor
- University of Texas Southwestern Medical Center
ADHD Specifically With Executive Function Impairment
Safety and Efficacy of SPD489 on Executive Function Behaviors in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
The primary objective of the study is to evaluate the efficacy of SPD489 compared to placebo on executive function (self-regulation) behaviors in adults with ADHD who report clinically significant impairment of executive function…
- Trial name
- NCT01101022
- Testing
- SPD489
- Where
- 39 sites in United States
- Volunteers
- 161 people
- Sponsor
- Shire
Adolescent Behavior
Curriculum Evaluation of a Novel Health and Wellness Program Within New York City Schools
The purpose of this study is to compare the academic and psycho-social benefits of a yoga-informed health and wellness program (HWP) to a standard physical education program for middle and high school students within New York…
- Trial name
- NCT02329015
- Testing
- Yoga-informed Health and Wellness Program, Physical Education Class
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Long Island University
PreDiabetes
MINDD 3: Prediabetes and Delay Discounting
The proposed research will translate research on delay discounting to the prevention of Type 2 diabetes (T2D) in persons with prediabetes.
- Trial name
- MINDD (NCT03664726)
- Testing
- Episodic Future Thinking, Episodic Recent Thinking, Scarcity Narrative
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Leonard Epstein