Clinical trials: Regulation of Inflammatory Response
Severe Sepsis, Pancreatitis
A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis
The role of complement system in bridging innate and adaptive immunity has been confirmed in various invasive pathogens. The aim of this study is to investigate the alteration of complement C3 in patients with severe abdominal…
- Conditions
- Severe Sepsis, Pancreatitis, Abdominal Abscess, Appendicitis
- Trial name
- NCT01568853
- Testing
- Norepinephrine, Open abdomen, enteral nutrition
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Jinling Hospital, China
Sepsis
Xuanbai Yiqi Decoction for Sepsis: A Randomized Controlled Trial
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Multiple organ dysfunction syndrome (MODS) is the leading cause of sepsis-related death.
- Trial name
- TCM-CIM-SEPSIS (NCT07902024)
- Testing
- Xuanbai Chengqi Decoction, Xuanbai Chengqi Decoction; Forest-Cultivated Ginseng, Xuanbai Yiqi Decoction
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Crohn's Disease
Immune Response Regulation and Nutritional Status of the Crohn's Disease Patients.
The objective of this study was to evaluate the effect of Whey Protein (WP) and Soy Protein (SP) nutritional supplements on nutritional status and disease activity in Crohn's disease patients.
- Trial name
- NCT01957423
- Testing
- Whey protein, Soy protein
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Campinas, Brazil
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Colon Cancer
Physiological Effects of Altering Cancer-related Inflammation
This prospective pilot study will examine whether the previously reported effects of NSAIDs on colorectal cancer may be modulated through alterations in tissue gene expression, up regulation of local immune cell infiltrates or…
- Trial name
- NCT01786200
- Testing
- Aspirin, Ibuprofen
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS Greater Glasgow and Clyde