Clinical trials: Reinfection
Primary Immune Deficiencies, Autoimmune Diseases
Investigation of Immune Disorders and Deficiencies
The immune system is an intricate system comprised of specialized cells, proteins, tissues and organs. Proper functioning is critical to the body's ability to defend itself against harmful pathogens.
- Conditions
- Primary Immune Deficiencies, Autoimmune Diseases, Inflammatory Diseases, Common Variable Immune Deficiencies
- Trial name
- NCT01981785
- Where
- United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- O & O Alpan LLC
COVID-19 (Coronavirus Disease 2019)
Levels of Physical Activity After SARS-CoV-2 Infection in Pre-illness Vaccinated and Unvaccinated Greek Adults.
Coronavirus infection has an impact on several aspects of everyday life including the levels of Physical Activity (PA). Investigators wish to (1) detect changes on PA levels in recovered SARS-CoV-2 (COVID-19) adults compared to…
- Trial name
- NCT05787431
- Where
- Greece
- Volunteers
- 2,000 people
- Sponsor
- Emmanouil D. Zacharakis
Tuberculosis
Exogenous Reinfection of Tuberculosis in Taiwan
we hypothesize that exogenous reinfection is very important in the Taiwan endemic. Therefore, we design a series of studies to evaluate the individual contribution of exogenous reinfection and endogenous reactivation in the…
- Trial name
- NCT00173433
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Clostridium Difficile Infection
MET-2 Clinical Study for Recurrent Clostridium Difficile Infection (CDI)
MET-2 clinical study is an Open label, single center, multiple dose pilot study of 19 patients. The study is designed to measure the resolution of diarrhea as well as the feasibility of administration and safety of MET-2 for the…
- Trial name
- NCT02865616
- Testing
- MET-2, Vancomycin
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- NuBiyota
Hip Prosthesis Infection
Prosthetic Hip Infections: Prospective Study
Data from large prospective cohort studies of prosthetic joint infections are lacking. Aim of this study: analyzing prospectively the incidence of reinfection in patients with prosthetic hip infections who underwent surgery and…
- Trial name
- PHIPS (NCT01963520)
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Prosthetic-joint Infection, Dysbiosis
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
Prosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty (TJA) of the hip and knee. Standard of care (SOC) treatment includes surgery and antimicrobials.
- Trial name
- NCT06636669
- Testing
- Probiotic, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Boston Medical Center
Malaria
Chlorproguanil-Dapsone in Pregnant Women
Controlling malaria during pregnancy is a vital strategy in decreasing maternal and child mortality in Africa. There are data from clinical trials and program evaluations in stable transmission areas that show that intermittent…
- Trial name
- NCT00126971
- Testing
- chlorproguanil-dapsone
- Where
- Mali
- Volunteers
- 132 people
- Sponsor
- Centers for Disease Control and Prevention
Enterobacteriaceae Infections, Bloodstream Infection
Antibiotic Treatment Duration (7 vs 14 Days) Comparison in Blood Stream Infection Causes by Enterobacteriaceae
The antimicrobial crisis is a real problem. Infections produced by multiresistant bacteria are becoming more and more frequent, and available antimicrobial agents are usually scarce.
- Trial name
- SHORTEN (NCT02400268)
- Testing
- 7 days course of antibiotic treatment, 14 days course of antibiotic treatment
- Where
- 4 sites in Spain
- Volunteers
- 238 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection
The frequency of Chlamydia trachomatis and Neisseria gonorrhoeae coinfection can vary depending on their individual incidence and prevalence rates.Single-agent therapy with ceftriaxone is the preferred regimen for treatment of…
- Trial name
- NCT05216744
- Testing
- Ceftriaxone 1000mg + doxycycline 100 mg, Cefixime 800mg + doxycycline 100 mg
- Where
- Vietnam
- Volunteers
- 125 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Clostridium Difficile Infection, Recurrent Clostridium Difficile Infection
Fecal Filtrate as a Treatment Option of Multiple Recurrent Clostridioides Difficile Infection
Clostridioides difficile infection (CDI) is one of the most common hospital-acquired infectious diseases with a high mortality rate (6-30%).
- Trial name
- FILTRATE (NCT04960306)
- Testing
- Fecal filtrate transplantation, Conventional fecal microbiota transplantation
- Where
- Hungary
- Volunteers
- 238 people
- Sponsor
- University of Pecs
Hepatitis C, Chronic
Direct-acting Antiviral Therapy and Reinfection Among People With Chronic Hepatitis C Virus Infection and Recent Injecting Drug Use in the Prison Setting
SHARP-P is an observational cohort study investigating the effect of direct-acting antiviral (DAA) therapy and reinfection in people with chronic hepatitis C virus (HCV) and recent injecting drug use.
- Trial name
- SHARP-P (NCT03740906)
- Where
- Australia
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Kirby Institute