Clinical trials: Relationship Conflict
Healthy
Punicalagin and Hydroxytyrosol Mixture on Different Inflammatory Markers
A crossover trial was carried out in healthy volunteers aged 45-70 years and BMI <30 kg/m2. Subjects consumed a Antioxidant Supplement (AS) containing 65 mg of punicalagin mixed with 3.3 mg of hydroxytyrosol 3 times daily or a…
- Trial name
- PROBELTEII (NCT02042742)
- Testing
- punicalagin and hydroxytyrosol mixture, Control supplement (maltodextrin)
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Tricuspid Regurgitation, Pacemaker
Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes
Tricuspid regurgitation (TR) is a common complication following cardiac implantable electronic device (CIED) implantation, with severe TR being associated with increased rates of heart failure hospitalization and all-cause…
- Trial name
- NCT06922526
- Testing
- Pacemaker implantation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Haiyan Wang
Edentulous Jaw
Impact of Different Palatal Contour Designs on Patients' Satisfaction and Oral Health Related Quality of Life
The palatal rugae, refer to asymmetrical and irregular elevations of the mucosa located in the anterior third of the palate, on each side of the median palatal raphe and behind the incisive papilla.
- Trial name
- NCT04985747
- Testing
- Polished palatal surface, Roughened palatal surface, Opened palatal surface
- Where
- Jordan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Renal Injury
Different Vascular and Renal Parameters in Living Kidney Donors
Chronic kidney disease (CKD) has a high prevalence globally and is a global health concern. CKD is associated with increased risks of cardiovascular morbidity, mortality and therefore decreased quality of life in any stage of the…
- Trial name
- NCT06056466
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Wound Heal, Quality of Life
Clinical Wound Healing After Lower 3rd Molar Fully-impacted Surgery With 2 Types of Flap
The dehiscence distal to the second molar after lower third molar extraction is very common because the access flap for surgical extraction cannot be repositioned on a portion of healthy bone to guarantee suture support.
- Conditions
- Wound Heal, Quality of Life, Dehiscence
- Trial name
- NCT04314765
- Testing
- lower third molar extraction
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Mild Traumatic Brain Injury
Change in Connectivity After mTBI Depending on Cognitive Reserve
The purpose of this study is to investigate the role of cognitive reserve in change in connectivity in the brain (measured with functional magnetic resonance imaging, fMRI) and how this is related to symptoms and symptom…
- Trial name
- NCT05593172
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Danderyd Hospital
Diabetes Mellitus Type 1
A Double-blinded, Randomised, Four-period Crossover Euglycemic Clamp Trial Investigating the Dose-response and Dose-exposure Relationship of BioChaperone Insulin Lispro in Three Different Doses in Subjects With Type 1 Diabetes
The addition of BioChaperone to insulin lispro may accelerate the onset and shorten the duration of action of insulin lispro due to facilitation of the absorption of the insulin after subcutaneous injection.
- Trial name
- NCT02146651
- Testing
- BioChaperone insulin lispro 0.2U/Kg, BioChaperone insulin lispro 0.1U/Kg, BioChaperone insulin lispro 0.4U/Kg
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Adocia
Pelvic Floor Muscle Weakness
Relationship Between Trunk Muscles and Pelvic Floor Strength
In recent years, the pelvic floor has emerged as a focal point for both academic research and clinical practice. This dynamic, hammock-like structure, comprising the pubococcygeus, iliococcygeus, coccygeus, and puborectalis…
- Trial name
- PelvicFloor (NCT07212621)
- Where
- Cyprus
- Volunteers
- 25 people
- Sponsor
- Eastern Mediterranean University
Severe Preeclampsia
The Association Between Different Markers With Development of Maternal and Neonatal Complications in Women With Severe Preeclampsia
pregnant women diagnosed with severe preeclampsia were subjected to • Full history taking including a detailed history of the hypertension state during the current pregnancy (onset, course, current medication, and whether the…
- Trial name
- NCT07125599
- Where
- Egypt
- Volunteers
- 284 people
- Sponsor
- Cairo University
Pain, Postoperative, Analgesic Effect
Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty is a commonly performed orthopaedic surgery for the treatment of end-stage osteoarthritis when conservative management becomes ineffective.
- Conditions
- Pain, Postoperative, Analgesic Effect, Total Knee Arthroplasty, Liposomal Bupivacaine
- Trial name
- NCT06740214
- Testing
- 0.5% standard bupivacaine only, 1.33% liposomal bupivacaine with 0.5% standard bupivacaine, 1.33% liposomal bupivacaine only
- Where
- Hong Kong
- Volunteers
- 177 people
- Sponsor
- The University of Hong Kong
Mechanical Ventilation, Mechanical Power
Investigation of the Optimum PEEP Mechanical Power Relationship
The aim of this study is to compare the effects of standard and optimum positive end expiratory pressures on mechanical power during laparoscopic surgeries.
- Conditions
- Mechanical Ventilation, Mechanical Power, Optimum PEEP, Laparoscopic Abdominal Surgery
- Trial name
- NCT06625099
- Testing
- Mechanical Ventilation (MV) with Low PEEP, Mechanical Ventilation (MV) with Optimum PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Kocaeli City Hospital
Tinnitus, Acoustic Stimulation
Different Stimuli Were Given to Patients With Chronic Pure Tone Tinnitus to Verify the Effective Treatment of Tinnitus.
In this experiment, patients with chronic pure tone tinnitus were divided into three groups to receive auditory stimulation, somatosensory stimulation, vestibular stimulation and combined stimulation, in order to find an…
- Conditions
- Tinnitus, Acoustic Stimulation, Somatic Stimulation, Vestibular Stimulation
- Trial name
- NCT04118907
- Testing
- multiple sensory stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Dan Su
Disorders Associated With Peritoneal Dialysis
The Association Between Arterial Stiffness and Assessment of Hydration State in Peritoneal Dialysis Patients
Dry weight (DW) assessment is essential for the efficient treatment of peritoneal dialysis (PD) patients but so far objective methods for DW assessment have not been established for daily clinical practice.
- Trial name
- NCT01659333
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Chronic Stroke
Differential Effectiveness of Robotic Assisted Therapy on Upper Extremity Function in Patients With Chronic Stroke
The objectives of this study are to: determine the effects of exoskeleton vs. end effector training systems on upper extremity motor and physiological function, daily functions, quality of life and self-efficacy in patients with…
- Trial name
- NCT04260061
- Testing
- training systems
- Where
- Taiwan
- Sponsor
- Chang Gung Memorial Hospital
Molar Incisor Hypomineralization
Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients
The goal of this clinical trial is to examine the clinical success of different pre-treatments in resin infiltration therapy applied to the incisors of pediatric patients with Molar Incisor Hypomineralization (MIH) and to…
- Trial name
- NCT07469124
- Testing
- Resin Infiltration, Microabrasion Followed by Resin Infiltration, Air Abrasion Followed by Resin Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Inonu University
Opioid-Related Disorders, Substance-Related Disorders
Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000255
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Opioid Use Disorder, Chronic Pain
Phase II Pharmacokinetics Study of CAM2038
Phase II, open label, partially randomized, three treatment group study designed to evaluate the steady state pharmacokinetics of buprenorphine and norbuprenorphine following repeated subcutaneous administrations of CAM2038.
- Trial name
- NCT02710526
- Testing
- CAM2038
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- Braeburn Pharmaceuticals
SCI - Spinal Cord Injury, PD - Parkinson's Disease
Differential Assessment of Hypertonia
Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements.
- Trial name
- NCT06596187
- Testing
- Continuous passive motion device (CPM) of ankle - fast, Continuous passive motion device (CPM) of ankle - slow
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Deep Sedation, Electroencephalography
ERPS, BIS and Entropy for Neuromonitoring in ICU Patients
Most critically ill patients receive sedative and analgesic drugs to attenuate discomfort and pain. The excessive use of sedatives and analgesics has undesirable effects for patients.
- Conditions
- Deep Sedation, Electroencephalography, Event-Related Potentials, Evoked Potentials, Auditory
- Trial name
- NCT00639548
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy
Single and Multiple Dose Study of VER-01 in Healthy Volunteers
Evaluation of pharmacokinetics, tolerability and safety of VER-01 in healthy volunteers
- Trial name
- NCT04930809
- Testing
- VER-01
- Where
- Austria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vertanical GmbH