Clinical trials: Remimazolam
Sedation in the Upper Gastrointestinal Endoscopy
A Study of Remimazolam Tosilate for Sedation in the Upper Gastrointestinal Endoscopy
The purpose of this study is to evaluate the efficacy and safety of Remimazolam Tosilate for Injection for sedation in Upper Gastrointestinal Endoscopy
- Trial name
- NCT06169995
- Testing
- Remimazolam Tosilate
- Where
- 2 sites in China
- Volunteers
- 31 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Sedation in Non-intubated Diagnostic and Therapeutic Procedures
A Study of Remimazolam Tosilate for Sedation in Non-intubated Diagnostic and Therapeutic Procedures
The purpose of this study is to evaluate the efficacy and safety of Remimazolam Tosilate for Injection for sedation in non-intubated diagnostic and therapeutic procedures
- Trial name
- NCT06216444
- Testing
- Remimazolam Tosilate for Injection
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Sedation in the ICU
A Study of Remimazolam Tosilate for Prolonged Sedation in the ICU
The purpose of this study is to evaluate the efficacy and safety of Remimazolam Tosilate for Injection for prolonged sedation(≥72h) during mechanical ventilation in the ICU.
- Trial name
- NCT05913336
- Testing
- Remimazolam Tosilate
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Hepatic Impairment, Healthy
An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment
To evaluate and compare the pharmacokinetics and safety of ONO-2745/CNS 7056 in subjects with the hepatic impairment and matched healthy subjects.
- Trial name
- NCT01790607
- Testing
- ONO-2745 /CNS 7056
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ono Pharma USA Inc
Sedation in the ICU
A Study of Remimazolam Tosilate for Sedation in the ICU
The purpose of this study is to evaluate the efficacy and safety of Remimazolam Tosilate for Injection for sedation in the ICU.
- Trial name
- NCT06222294
- Testing
- Remimazolam Tosilate, Propofol Medium and Long Chain Fat Emulsion Injection
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Colonoscopy
Safety and Efficacy of Remimazolam in ASA III and IV Patients Undergoing Colonoscopy
A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in American Society of…
- Trial name
- NCT02532647
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Paion UK Ltd.
Anesthesia
Study of the Efficacy and Safety of Remimazolam in General Anesthesia in Adults Undergoing Cardiac Surgery
This study investigates the use of remimazolam as a sedative/hypnotic in general anesthesia. Remimazolam or propofol will be administered together with fentanyl/sufentanil/remifentanil as opioid analgesics and a neuromuscular…
- Trial name
- NCT02523859
- Testing
- Propofol, Remimazolam
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Paion UK Ltd.
General Anaesthesia
Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia
The purpose of this study was to perform comparative evaluation of clinical efficacy and safety of Remimazolam and Propofol for induction and maintenance of general anesthesia in patients undergoing elective surgery under general…
- Trial name
- NCT03669484
- Testing
- Remimazolam, Propofol, Fentanyl
- Where
- 6 sites in Russia
- Volunteers
- 150 people
- Sponsor
- R-Pharm
Sedation
A Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy
The purpose of this study is to find out the optimal dose for Remimazolam Tosilate as a procedural sedative during a diagnostic upper GI endoscopy and to assess its efficacy and safety profile comparing to propofol.
- Trial name
- NCT03003884
- Testing
- Remimazolam Tosilate, Propofol
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
General Anesthesia
Remimazolam Phase II Cardiac Anesthesia Study
This phase II study in patients undergoing elective cardiac surgery will evaluate the efficacy, safety, and pharmacokinetics of remimazolam, compared with propofol and sevoflurane, during the induction and maintenance of general…
- Trial name
- NCT01937767
- Testing
- Remimazolam, Propofol, Sevoflurane
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Paion UK Ltd.
Operative Sedation of Pediatric, Operative Sedation of Adolescent Patients
A Trial of Remimazolam for Intraoperative Sedation in Pediatric and Adolescent Patients
The study is being conducted to evaluate the efficacy and safety of Remimazolam for intraoperative sedation in pediatric and adolescent patients.
- Trial name
- NCT07036419
- Testing
- Remimazolam Tosilate for injection, Propofol Injection
- Where
- China
- Volunteers
- 249 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Colonoscopy
A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients
A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in patients undergoing a colonoscopy…
- Trial name
- NCT02290873
- Testing
- Remimazolam, Midazolam
- Where
- 13 sites in United States
- Volunteers
- 461 people
- Sponsor
- Paion UK Ltd.
Sedation
Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy
The purpose of this study is to evaluate the safety and efficacy of the sedation for Remimazolam or Propofol in patients undergoing diagnostic upper GI endoscopy.
- Trial name
- NCT03425474
- Testing
- Remimazolam Tosilate, Propofol
- Where
- China
- Volunteers
- 378 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.