Clinical trials: Remote Ischaemic Preconditioning
Tissue Donors, Liver Transplantation
The Effect of Remote Ischemic Preconditioning in Living Donor Hepatectomy
Liver transplantation is the gold standard treatment for patients with end-stage liver disease. Despite its outstanding success, liver transplantation still entails certain complications including ischemia-reperfusion injury.
- Conditions
- Tissue Donors, Liver Transplantation, Ischemia Reperfusion Injury
- Trial name
- NCT03386435
- Testing
- remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Asan Medical Center
Physical Performance, Rhabdomyolysis
The Effect of Remote Ischemic Preconditioning on Physical Performance and Exertional Rhabdomyolysis
In order to examine the effect of RIPC on skeleton muscle exertional damage and on aerobic and anaerobic physical performances, 30 healthy volunteers will undergo a series of different physical tests twice; once without…
- Trial name
- NCT02518724
- Testing
- RIPC intervention exposure
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cerebrovascular Disease, Stroke
Remote Ischemic Limb Preconditioning In Healthy Volunteers
The investigators would like to determine if remote ischemic leg preconditioning in healthy volunteers improves cerebral vasomotor reactivity as measured by breath holding and transcranial doppler vasomotor reactivity.
- Trial name
- NCT02553655
- Testing
- 4x 5min Limb Preconditioning, 3x 10min Limb Preconditioning
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pressure; Brachial Plexus
The Effect of Remote Ischemic Preconditioning (RIPC) on Blood Pressure and Its Vascular Protection Effect
The purpose of this study is to determine the effect of remote ischemic preconditioning (RIPC) on blood pressure and its vascular protection effect among Chinese young healthy adults and primary hypertensive patients stage I.
- Trial name
- NCT02414997
- Testing
- RIPC
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Hemodialysis
Intradialytic Exercise and Remote Ischaemic Preconditioning: a Cardioprotective Role ?
The aim of this clinical trial is to evaluate whether intermittent exercise and remote ischaemic preconditioning (rIPC) during haemodialysis (HD) can provide cardioprotection in adult patients (aged 20-79 years) undergoing HD for…
- Trial name
- EXPI-DIAL (NCT06856512)
- Testing
- Remote ischaemic preconditioning, Exercise, standard dialysis
- Where
- 3 sites in France
- Volunteers
- 33 people
- Sponsor
- University of Avignon
Renal Function, Renal Injury
Analysis of Remote-ischemic Preconditioning Effects on Kidney Function
Patients with impaired renal function are at elevated risk for development of acute kidney injury (AKI). AKI is associated with increased risk for cardiovascular morbidity and mortality.
- Trial name
- RenPRO-TAVI (NCT01925235)
- Testing
- remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Critically Ill, Acute Kidney Injury
Remote Ischemic Preconditioning in Septic Patients
Acute kidney injury is a well-recognized complication in critically ill patients. Up to date there is no clinically established method to reduce the incidence or the severity of acute kidney injury.
- Conditions
- Critically Ill, Acute Kidney Injury, Sepsis
- Trial name
- RIPC-ICU (NCT05830669)
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Universität Münster
Remote Ischemic Preconditioning, Contrast Induced - Acute Kidney Injury
Remote Ischemic Preconditioning and Contrast Induced - Acute Kidney Injury in Patients Undergoing Elective PCI
Prospective, randomized, sham-controlled clinical study was conducted to assess whether RIPC reduces the incidence of CI-AKI measured standard way of using SCr concentration but also with the use of serum NGAL as a new potential…
- Trial name
- NCT03761368
- Testing
- Remote Ischemic Preconditioning
- Where
- Poland
- Volunteers
- 101 people
- Sponsor
- Medical University of Lodz
Hemodialysis, Cardiovascular Diseases
Remote Ischaemic Preconditioning to Prevent Dialysis Induced Cardiac Injury
This study evaluates the use of remote ischaemic preconditioning for the prevention of dialysis induced cardiac injury. The study uses four arms to test different frequencies of application to ascertain which, if any, is most…
- Trial name
- NCT02630355
- Testing
- Remote Ischaemic Preconditioning
- Volunteers
- 32 people
- Sponsor
- Western University, Canada
Lung Neoplasms
Effect of Remote Ischemic Preconditioning on Lung Injury After Pulmonary Resection
The purpose of this study is to determine whether ischemic preconditioning reduces lung injury in patients undergoing pulmonary resection.
- Trial name
- NCT01307085
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Cai Li
Aortic Valve Disease, Myocardial Ischemia
Remote Ischemic Preconditioning in Patients Undergoing Isolated Aortic Valve Replacement Surgery
The goal is to investigate the efficacy, safety and possible neuro- and cardioprotective effects of remote ischemic preconditioning (RIPC) in adult cardiac patients undergoing isolated aortic valve replacement surgery with a…
- Trial name
- NCT02694016
- Testing
- Remote ischemic preconditioning
- Where
- Finland
- Volunteers
- 4 people
- Sponsor
- Oulu University Hospital
Cardiac Surgery
Remote Ischemic Preconditioning in Cardiac Surgery Trial
Main Research Questions: 1. Is a large trial of patients undergoing heart surgery comparing a simple procedure of temporarily stopping blood flow to the leg with a blood pressure cuff (called remote ischemic preconditioning) to a…
- Trial name
- Remote IMPACT (NCT01071265)
- Testing
- Remote Ischemic Preconditioning
- Where
- 7 sites in United States, Canada
- Volunteers
- 250 people
- Sponsor
- McMaster University
Liver Transplant; Complications, Ischemia Reperfusion Injury
The Effect of Remote Ischemic Preconditioning on Ischemia/Reperfusion Injury in a Liver Transplant Recipient
Ischemia and reperfusion injury is unavoidable during a liver transplantation. Remote ischemic preconditioning, a safe and feasible method, has previously been shown to reduce ischemia and reperfusion injury.
- Trial name
- NCT03758352
- Testing
- remote ischemic preconditioning (rIC), non remote ischemic preconditioning (non-rIC)
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease, Diabetes Mellitus
The Effect of Remote Ischemic Preconditioning on Diastolic Function in Coronary Artery Bypass Surgery Between Diabetic and Non-Diabetic Patients
This randomized controlled study aims to evaluate the effects of Remote Ischemic Preconditioning (RIPC) on diastolic function in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Diastolic Function
- Trial name
- NCT06841757
- Testing
- Remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alzahraa Khalil Marie
Heart Diseases, Atrial Fibrillation
Clinical Value of Remote Ischemic Preconditioning
Objectives: Despite utilization of available means for cardioprotection during cardiac surgery, myocardial injury still occurs. Further improvement of cardioprotection is therefore necessary.
- Trial name
- NCT01740102
- Testing
- RIPC
- Where
- Norway
- Volunteers
- 92 people
- Sponsor
- Norwegian University of Science and Technology
Renal Cell Carcinoma
Remote Ischemia Pre-Conditioning in Patients Undergoing Partial Nephrectomy
Partial Nephrectomy has become the standard treatment in patients with tumours <7cm (T1). Even though this is a nephron sparing surgery, there is still potential for acute kidney injury, due to ischemia during the surgery.
- Trial name
- NCT01771003
- Testing
- CellAegis' autoRIC™ Device
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University Health Network, Toronto
Myocardial Reperfusion Injury
Investigation Into the Role of GTN & RIPC in Cardiac Surgery
The purpose of this study is to determine whether Glyceryl Trinitrate (GTN) reduces injury to the heart during heart-lung bypass surgery in combination with the newer technique of remote ischaemic preconditioning (RIPC).
- Trial name
- ERIC-GTN (NCT01864252)
- Testing
- Remote ischaemic preconditioning, IV Normal saline, IV Glyceryl trinitrate 2-5ml/h
- Where
- United Kingdom
- Volunteers
- 192 people
- Sponsor
- University College, London
Hepatocellular Cancer
Effect of Remote Ischaemic preConditioning on Liver Injury in Patients Undergoing LIVER Resection Surgery
Liver resection has improved health outcomes in patients with hepatocellular carcinoma (HCC) in Singapore and worldwide. However, due to acute ischaemia/reperfusion injury (IRI) to the liver at the time of surgery, patients still…
- Trial name
- NCT03594929
- Testing
- Active RIC
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Vestibular Schwannoma
Remote Ischemic Preconditioning in Vestibular Schwannoma Surgery
Vestibular schwannomas are primarily benign (WHO grade I) tumors originating from the Schwann cells of the vestibular nerve and are among the most common tumors of the skull base.
- Trial name
- RIC-VS (NCT05567341)
- Testing
- Remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
Aortic Valve Stenosis, Cardiopulmonary Bypass
The Effect of Remote Ischemic Preconditioning in Aortic Valve Replacement Surgery
The study objective is to verify if a non-invasive remote ischemic preconditioning procedure (blood pressure cuff on the arm) is cardioprotective when applied before an aortic valve replacement surgery.
- Trial name
- NCT03305094
- Testing
- Blood pressure cuff inflation
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Laval University