Clinical trials: Renal Carcinoma
Marriage, Kidney Neoplasms
The Association of Marital Status With Kidney Cancer Surgery Morbidity
Retrospective cohort study
- Conditions
- Marriage, Kidney Neoplasms, Surgery-Complications, Cohort Studies
- Trial name
- NCT05526599
- Volunteers
- 106,752 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Prostate Cancer, Renal Cell Cancer
Development of Urologic Registry for Personalized Medicine in Patients With Urological Malignancy by Analyzing Circulating Tumor DNA
Urological malignancies such as prostate cancer and renal cell cancer in Korean population have been increased due to the aged population and the westernized lifestyles.
- Conditions
- Prostate Cancer, Renal Cell Cancer, Bladder Cancer, Ureter Cancer
- Trial name
- NCT04197414
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Yonsei University
Metastatic Renal Cell Carcinoma
Validation of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) Prognostic Classification for Targeted Therapies (TKI/mTOR Inhibitors) in Second Line After First Line Treatment With Pazopanib
This is a nation-wide retrospective observational study which will be performed in 50 centres in Spain, geographically representative of all regions, with at least 5 patients treated with first-line pazopanib for mRCC in daily…
- Trial name
- Spazo-2 (NCT03091465)
- Where
- 57 sites in Spain
- Volunteers
- 530 people
- Sponsor
- Spanish Oncology Genito-Urinary Group
Metastatic Renal Cell Carcinoma
Inflammatory Markers (ICC, MCVL) and Nivolumab Response: Predicting Immunotherapy Success in Metastatic RCC
This study is an observational study aimed at investigating the potential of new inflammatory markers to predict treatment response in patients with metastatic renal cell carcinoma (mRCC) undergoing anti-PD-1 antibody nivolumab…
- Trial name
- IMNR (NCT06607809)
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Renal Cell Carcinoma
Circulating and Urinary Exosomal miRNA as Predictors of Treatment Response in Advanced Kidney Cancer
This study investigates the role of circulating and urinary exosomal microRNAs (miRNAs) as potential biomarkers for predicting response to systemic therapy in patients with advanced renal cell carcinoma.
- Trial name
- EXO-RENAL2 (NCT07436416)
- Testing
- Circulating and Urinary Exosomal miRNA Analysis
- Where
- Slovenia
- Volunteers
- 91 people
- Sponsor
- Institute of Oncology Ljubljana
Carcinoma, Carcinoma, Renal Cell
Savolitinib vs. Sunitinib in MET-driven PRCC.
This study is designed for patients diagnosed with MET-driven, unresectable and locally advanced or metastatic Papillary Renal Cell Carcinoma.
- Conditions
- Carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms, Urologic Neoplasms
- Trial name
- NCT03091192
- Testing
- Savolitinib, Sunitinib
- Where
- 59 sites in United States, Brazil and 5 more
- Volunteers
- 60 people
- Sponsor
- AstraZeneca
Renal Cell Carcinoma, Kidney Cancer
Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC
The purpose of this study is to see whether the drug casdatifan is safe and effective either by itself or in combination with the drug zimberelimab in participants with resectable clear cell renal cell carcinoma (ccRCC).
- Conditions
- Renal Cell Carcinoma, Kidney Cancer, Kidney Neoplasm, Renal Carcinoma
- Trial name
- NCT07397611
- Testing
- Casdatifan, Zimberelimab
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Dana-Farber Cancer Institute
Central Nervous System/Leptomeningeal Neoplasms
131I-omburtamab for the Treatment of Central Nervous System/Leptomeningeal Neoplasms in Children and Young Adults
The researchers are doing this study to provide access to treatment with 131I-omburtamab for children and young adults who have CNS/leptomeningeal neoplasms.
- Trial name
- NCT05064306
- Testing
- 131I-omburtamab
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Clear Cell Renal Cell Carcinoma
68Ga-P16-093 and 18F-FDG PET/CT Imaging in the Same Group of Clear Cell Renal Cell Carcinoma Patients
PSMA is highly expressed on the cell surface of the microvasculature of several solid tumors, including clear cell renal cell carcinoma (ccRCC). This makes it a potentially imaging target for the detection of ccRCC.
- Trial name
- NCT05432947
- Testing
- 68Ga-P16-093, 18F-FDG
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Peking Union Medical College Hospital
Active Surveillance, Clear Cell Renal Cell Carcinoma
Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC)
To learn if belzutifan can help to control the disease in patients with metastatic RCC who are considered candidates for active surveillance and have not undergone previous systemic treatment.
- Trial name
- NCT07023432
- Testing
- Belzutifan, Active Surveillance
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- M.D. Anderson Cancer Center
ccRCC
Pembrolizumab Plus Lenvatinib in REcurrent ccRCC Patients Failing permbroLizUmab aDjuvant trEatment
This study is being performed as a single-arm open-label study in order to provide information on the potential benefits of the combination of pembrolizumab and lenvatinib in participants with advanced ccRCC who have progressed…
- Trial name
- PRELUDE (NCT07460206)
- Testing
- Pembrolizumab 200 mg Q3W, Lenvatinib 20mg QD
- Volunteers
- 108 people
- Sponsor
- Gruppo Oncologico Italiano di Ricerca Clinica
Kidney Cancer
RPI.4610 in Treating Patients With Metastatic Kidney Cancer
RATIONALE: RPI.4610 may stop the growth of metastatic kidney cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of RPI.4610 in treating patients who have metastatic kidney cancer.
- Trial name
- NCT00021021
- Testing
- anti-FLT-1 ribozyme
- Where
- United States
- Sponsor
- Ribozyome
Renal Cell Carcinoma
Anesthesia and Cancer Study: Renal Cell Carcinoma
This study investigates the influence of type of anesthesia on recurrence and survival of renal cell carcinoma in patients undergoing nephrectomy.
- Trial name
- NCT04503148
- Testing
- Propofol, Inhaled General Anesthetics
- Where
- South Korea
- Volunteers
- 562 people
- Sponsor
- Seoul National University Hospital
Phase II, Sacituzumab
Phase II Trial of Sacituzumab Tirumotecan in Patients With SMARCB1-Deficient Renal Medullary Carcinoma
To learn if sacituzumab tirumotecan can help to control advanced or metastatic SMARCB1-deficient RMC in patients whose disease has progressed after receiving at least 1 treatment.
- Conditions
- Phase II, Sacituzumab, Tirumotecan, SMARCB1-deficient Renal Medullary Carcinoma
- Trial name
- NCT07438626
- Testing
- Sacituzumab tirumotecan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Recurrent Renal Cell Carcinoma, Renal Cell Carcinoma
Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation
This phase II trial studies how well contrast-enhanced ultrasound (CEUS) works for diagnosing patients with renal cell cancer (RCC) that has come back (recurrent) after an ablation.
- Trial name
- NCT05641935
- Testing
- Sulfur Hexafluoride Lipid Microspheres, Contrast-Enhanced Ultrasound, Computed Tomography
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- john eisenbrey
Pediatric Solid Tumor, Germ Cell Tumor
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of…
- Conditions
- Pediatric Solid Tumor, Germ Cell Tumor, Retinoblastoma, Hepatoblastoma
- Trial name
- NCT04483778
- Testing
- second generation 4-1BBζ B7H3-EGFRt-DHFR, second generation 4-1BBζ B7H3-EGFRt-DHFR(selected) and a second generation 4-1BBζ CD19-Her2tG, Pembrolizumab
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Seattle Children's Hospital
Kidney Cancer, Melanoma (Skin)
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Metastatic Kidney Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy…
- Trial name
- NCT00004135
- Testing
- filgrastim, therapeutic allogeneic lymphocytes, cyclophosphamide
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago
Solitary Pulmonary Nodules, Multiple Pulmonary Nodules
Extracolonic Findings on Computed Tomography (CT) Colonography
The ACRIN 7151 trial will use medical records abstraction data from participants with extracolonic findings (ECFs) reported from the ACRIN 6664 National CT Colonography Trial to: 1) measure incidence of diagnostic imaging…
- Conditions
- Solitary Pulmonary Nodules, Multiple Pulmonary Nodules, Renal Neoplasms, Adrenal Gland Neoplasms
- Trial name
- ACRIN7151 (NCT01465425)
- Volunteers
- 520 people
- Sponsor
- American College of Radiology Imaging Network
Renal Cell Carcinoma
Role of Geminin and Mcm-2 in Prognosis of Renal Cell Carcinoma
The study aim is to prospectively assess the prognostic significance of immunohistochemical markers Geminin and Mcm-2 in cases of renal cell carcinoma and to detect its clinicopathological correlation.
- Trial name
- NCT03692533
- Testing
- Immunohistochemistry
- Volunteers
- 80 people
- Sponsor
- Assiut University
Metastatic Renal Cell Carcinoma, Metastatic Malignant Melanoma
Study of AS1409 in Patients With Either Metastatic Renal Cell Carcinoma or Metastatic Malignant Melanoma
To determine the tolerability, safety, end-organ toxicity and maximum tolerated dose of AS1409 in single and repeated doses.
- Trial name
- NCT00625768
- Testing
- AS1409
- Where
- 4 sites in New Zealand, United Kingdom
- Volunteers
- 13 people
- Sponsor
- Antisoma Research
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