Clinical trials: Renal Dysfunction
Thoracic Surgery With One-lung Ventilation, VExUS
Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute…
- Conditions
- Thoracic Surgery With One-lung Ventilation, VExUS, Fluid Management, Acute Kidney Injury
- Trial name
- VEXUS (NCT07258875)
- Testing
- Venous Excess Ultrasound, Standard of Care (SOC)
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Crete
Acute Kidney Injury
Improving Post Discharge Care After Acute Kidney Injury
The purpose of this trial is to test the clinical benefit and feasibility of structured risk based post discharge care for hospital acquired Acute kidney injury survivors.This is a Pragmatic randomized controlled trial.
- Trial name
- AFTER AKI (NCT02915575)
- Testing
- Risk guided follow-up, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 155 people
- Sponsor
- University of Alberta
Type 2 Diabetes Mellitus, Acute Kidney Injury
Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes
This pilot study will evaluate the feasibility of using a clinical decision support(CDS) message to support consideration of SGLT2 inhibitor prescribing in patients with type 2 diabetes who recently had acute kidney injury.
- Conditions
- Type 2 Diabetes Mellitus, Acute Kidney Injury, Chronic Kidney Diseases
- Trial name
- NCT07868666
- Testing
- Clinical Decision Support Message
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Minnesota
Hypovolemic Shock, Cardiogenic Shock
Renal Resistive Index in Patients With Shock
This study consists of two substudies. The first substudy: 'Renal resistive index in critically ill patients with cardiogenic and septic shock' Design: cross-sectional observational Aim of this project is: 1.
- Conditions
- Hypovolemic Shock, Cardiogenic Shock, Septic Shock, Kidney Failure, Acute
- Trial name
- NCT02558166
- Where
- Netherlands
- Volunteers
- 92 people
- Sponsor
- Amsterdam UMC, location VUmc
Anemia Associated With Chronic Kidney Disease
Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vadadustat in Hemodialysis Subjects With Anemia Associated With Chronic Kidney Disease
This study will be conducted to assess the pharmacokinetics of vadadustat 600, 750, and 900 milligrams daily, and intravenous erythropoiesis-stimulating agent (darbepoetin alfa or epoetin alfa), in hemodialysis participants with…
- Trial name
- NCT03992066
- Testing
- Vadadustat, Darbepoetin alfa, Epoetin alfa
- Where
- 10 sites in United States
- Volunteers
- 46 people
- Sponsor
- Akebia Therapeutics
Chronic Kidney Diseases
Helping Relationships From Significant Others on Healthy Lifestyle and Quality of Life Among Patients With CKD( CKD Lifestyle)
This clinical trial aims to evaluate the effectiveness of a helping relationships intervention program for patients with chronic kidney disease (CKD).
- Trial name
- CKD lifestyle (NCT02076256)
- Testing
- helping relationships
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Acute Kidney Injury, Drug Toxicity
Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate
This retrospective observational study will evaluate high-dose methotrexate patterns of use, supportive care measures used during high-dose methotrexate chemotherapy, along with the incidence of delayed elimination of…
- Trial name
- NCT05899751
- Testing
- High-dose methotrexate, Glucarpidase
- Where
- 5 sites in France, Italy and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Protherics Medicines Development Limited
End Stage Renal Disease
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
VasQ is an external support implant for arteriovenous fistulas created for dialysis access. This is a postmarket surveillance, prospective, multi-center, randomized, controlled, open label trial enrolling 300 patients randomized…
- Trial name
- NCT06516653
- Testing
- VasQ, Arteriovenous fistula creation for dialysis vascular access
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Laminate Medical Technologies
Renal Impairment
Study of Sulthiame (S-054502) in Participants With Renal Impairment and Matched Healthy Controls
The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability of sulthiame in participants with mild and moderate renal impairment compared to those in healthy participants with normal renal…
- Trial name
- NCT07857837
- Testing
- Sulthiame
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shionogi
Liver Transplantation, Acute Kidney Injury
Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation
To verify whether albumin administration to achieve serum concentration above 30g/L (treated group) and its maintenance within plasmatic physiologic range (above 30 g/L) for five days diminishes rate of AKI at Day 7 after liver…
- Trial name
- HALT (NCT06535945)
- Testing
- Albumin administration
- Where
- 8 sites in France
- Volunteers
- 400 people
- Sponsor
- Rennes University Hospital
Acute Kidney Injury, Cardiac Disease
New Markers of Cardiac Surgery Related Acute Kidney Injury.
Cardiac surgery related acute kidney injury (CS-AKI) is a clinical problem associated with a cardiopulmonary bypass used during cardiac surgery procedures.
- Trial name
- NCT03860545
- Testing
- urine and blood analysis
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Pomeranian Medical University Szczecin
End-Stage Renal Disease; Hemodialysis
Nurse-Led Nutrition and Exercise Program for Hemodialysis Patients
This randomized controlled trial aims to evaluate the effectiveness of a nurse-led integrated nutrition and exercise intervention on improving health-related quality of life among hemodialysis patients.
- Trial name
- HD-NEX (NCT07535957)
- Testing
- Nurse-Led Integrated Nutrition and Exercise Program, Usual Hemodialysis Care
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Misan
Subjects With Renal Impairment, Healthy Subjects
A Study in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function
The purpose of this study is to evaluate the pharmacokinetics and safety of a single dose of JT001 in adult subjects with mild and moderate renal impairment compared to healthy mean-matched subjects.The results of this study will…
- Trial name
- NCT05895812
- Testing
- Deuremidevir Hydrobromide Tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shanghai Vinnerna Biosciences Co., Ltd.
Anemia, Renal Insufficiency, Chronic
15141 Fixed Dose Correction / naïve and Pre Dialysis (Europe and Asia Pacific)
Anaemia is a condition in which blood has a lower than normal number of red blood cells. It can also occur if red blood cells do not contain enough haemoglobin, an oxygen carrying part of blood.
- Trial name
- DIALOGUE 1 (NCT02021370)
- Testing
- BAY85-3934
- Where
- 56 sites in Australia, Bulgaria and 12 more
- Volunteers
- 121 people
- Sponsor
- Bayer
Renal Insufficiency, Chronic
To Investigate Pharmacokinetics (Absorption, Distribution, Elimination), Safety and Tolerability of a Single Oral Dose of 75 mg Molidustat Tablet in Male and Female Subjects Requiring Hemo- or Peritoneal Dialysis Compared to Healthy Subjects
The study investigates the pharmacokinetics (absorption, distribution, elimination) of molidustat after intake of a single 75 mg tablet in subjects with renal impairment requiring hemo- or peritoneal dialysis compared to age-and…
- Trial name
- NCT02312973
- Testing
- Molidustat(BAY85-3934)
- Where
- 2 sites in Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayer
Chronic Kidney Disease
Artificial Intelligence Model to Predict Chronic Kidney Outcomes in a Vietnamese Cohort
Chronic kidney disease (CKD) is a common condition that imposes a substantial health burden and contributes significantly to global morbidity and mortality.
- Trial name
- NCT07751939
- Where
- Vietnam
- Volunteers
- 1,182 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Congestive Heart Failure, Renal Dysfunction
Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction
The purpose of the study is to show that low dose recombinant BNP coupled with phosphodiesterase V inhibition will improve renal dysfunction and promote relief of volume overload in patinets with acute decompensated heart failure…
- Trial name
- BNP+PDEVI (NCT00818701)
- Testing
- low dose Nesiritide, nesiritide, Sildenafil
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Critical Illness, Acute Kidney Injury
Collective Accuryn Physiologic Signals and Signatures
The CAPSS Study is a retrospective and prospective, multi-center, single-arm post-market data collection study with an FDA cleared device.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Septic Shock
- Trial name
- CAPSS (NCT03817281)
- Testing
- Accuryn Monitoring System
- Where
- United States
- Sponsor
- Potrero Medical
Acute Kidney Injury, COVID-19
Prediction of Acute Kidney Injury in Patients With COVID-19
The two biomarkers determined in urine, "Tissue Inhibitor of Metalloproteinases 2 (TIMP-2)" and "Insulin-like Growth Factor-Binding Protein 7 (IGFBP7)", can indicate the occurrence of Acute kidney injury (AKI) in cardiac surgery…
- Conditions
- Acute Kidney Injury, COVID-19, ARDS
- Trial name
- NCT04406688
- Where
- 13 sites in Germany, Italy and 3 more
- Volunteers
- 300 people
- Sponsor
- University Hospital Muenster
Kidney Failure, Chronic
Short Term Effects of FX Dialysers on QOL and Inflammation
Background: The new hollow fibre FX-class of dialysers (Fresenius Medical Care, Bad Homburg, Germany) features a number of technological improvements that may benefit the patient.
- Trial name
- NCT00291603
- Testing
- FX-class of dialyser
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Sir Charles Gairdner Hospital
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