Clinical trials: Renal Failure, End Stage
End Stage Renal Disease (ESRD), Metabolic Acidosis
the Effect of Interdialytic Serum Bicarbonate Correction on Vascular Calcification in Hemodialysis Patients
the investigators will test the effect of interdialytic metabolic acidosis correction on vascular calcification in hemodialysis patients
- Trial name
- NCT07765459
- Testing
- Oral sodium bicarbonate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
End Stage Renal Disease
Myfortic vs. Cellcept in Kidney Transplant Recipients
The comparison the incidence of G.I. toxicity between Myfortic® vs. Cellcept® in 150 sequential patients, in which 75 will be randomized to Cellcept® and 75 to Myfortic® in first and second living or deceased donor renal…
- Trial name
- NCT00533624
- Testing
- Mycophenolate Sodium Delayed Release Tablets, Mycophenolate Mofetil
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Haemodialysis Complication, Major Adverse Cardiac Events
Novel Cardiovascular Biomarkers in Patients With Kidney Disease
Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should. End-stage kidney failure (ESKD) is the final, irreparable stage of chronic kidney disease (CKD), where kidney function…
- Trial name
- CBKD (NCT06037759)
- Testing
- Cardiac Biomarkers, Lipidomics, Proteomics
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
End-Stage Renal Disease
Chinese Medicine on Deferring Dialysis Initiation
Stage 5 chronic kidney disease (CKD), also end stage renal disease(ESRD), usually presents overt clinical symptoms and is a critical stage when patients are encountered with dialysis.
- Trial name
- C-MODDI (NCT02194946)
- Testing
- CM therapies, CKD-related management
- Where
- 29 sites in China
- Volunteers
- 875 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
SARS-CoV 2, End Stage Renal Failure on Dialysis
Serological Testing for COVID-19 (SARS-CoV-2) in ESKD
Starting in late 2019, the world is facing a pandemic with the SARS-CoV-2 virus. Patients with end-stage kidney disease and on treatment with renal replacement therapy are high risk patients, as they are unable to maximize social…
- Trial name
- NCT04378686
- Testing
- dialysis
- Where
- 3 sites in Belgium
- Volunteers
- 500 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Artery Disease, Dialysis
Coronary Revascularization in Patients With Dialysis in China
China patients in end stage renal disease receiving maintenance dialysis have a high risk of cardiovascular disease (CVD), with a prevalence of 45.5% approximately, and coronary artery disease (CAD) has been identified as the…
- Conditions
- Coronary Artery Disease, Dialysis, Intervention
- Trial name
- CRUISE (NCT04953819)
- Testing
- Revascularization, Medical therapy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China-Japan Friendship Hospital
End Stage Renal Disease
Fluid Management Guided by Bioimpedance Analysis in Peritoneal Dialysis(PD) Patients.
1. Purpose: to investigate the effect of bioimpedance analysis(BIA) guided fluid management versus experiential way on clinical outcome in peritoneal dialysis patients. 2.
- Trial name
- NCT02000128
- Testing
- bioimpedance monitoring, clinical monitoring
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
End-Stage Renal Disease; Hemodialysis
Nurse-Led Nutrition and Exercise Program for Hemodialysis Patients
This randomized controlled trial aims to evaluate the effectiveness of a nurse-led integrated nutrition and exercise intervention on improving health-related quality of life among hemodialysis patients.
- Trial name
- HD-NEX (NCT07535957)
- Testing
- Nurse-Led Integrated Nutrition and Exercise Program, Usual Hemodialysis Care
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Misan
End-Stage Renal Disease Requiring Haemodialysis
Hemodialysis-Induced Renal Perfusion Decline: Unraveling the Pathophysiological Mechanisms Linking Intradialytic Circulatory Stress to Residual Renal Function Loss
Residual renal function (RRF) plays a critical role in quality of life and survival in hemodialysis (HD) patients but characteristically declines after the initiation of HD.
- Trial name
- HD-RPD (NCT07003828)
- Testing
- CEUS examinations
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Yuanjun Yang
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
ESRD (End Stage Renal Disease)
Fluid Status of ESRD Patients Undergoing Dialysis
The pilot clinical study will assess the correlation between fluid removal during dialysis and HemoCept device data.
- Trial name
- NCT07217470
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- HemoCept Inc.
End-stage Renal Disease
Comparison of Cardiac Index and Cardiac Output Effect During Maintenance Hemodialysis Between Acetate-Free and Acetate-Based Online Hemodiafiltration
The purpose of this study is to detemine whether effect of Acetate-free solution on cardiac index and cardiac output measured by saline dilution techniques compares with Acetate-based solution in online-hemodiafiltration
- Trial name
- NCT01778283
- Testing
- Acetate-free dialysis solution
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Chulalongkorn University
End-stage Renal Disease (ESRD)
Creating a Buttonhole Tunnel Track by Repeated Needling of the AV Fistula on the Same Day in Patients on Hemodialysis.
BACKGROUND: The patients diagnosed with end stage renal disease require dialysis and for that they need to have a vascular access for hemodialysis (HD) placed.
- Trial name
- NCT03989141
- Testing
- Repeated cannulation Buttonhole., Single cannulation Buttonhole.
- Where
- 2 sites in Denmark
- Volunteers
- 43 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Chronic Kidney Diseases
Effect of Intradialytic Continuous Versus Interval Aerobic Exercises on Functional Capacity in Patients With Chronic Renal Failure.
Chronic kidney disease has emerged as one of the leading causes of mortality worldwide, and it is one of a small number of non-communicable diseases that have shown an increase in associated deaths over the past 2 decades.
- Trial name
- NCT06173141
- Testing
- low- to moderate-continuous intensity cycling exercises:, moderate- to high-interval intensity cycling exercises, hemodialysis sessions only
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Cairo University
Chronic Renal Failure (CRF)
Evaluation of Electrostimulation Program During Dialysis Sessions in Chronic Renal Failure Patients
Sport improves quality of life and health, decreasing cardiovascular risks and increasing effort tolerance. Chronic renal failure (CRF) induces many clinical and biological complications leading to less effort tolerance (strength…
- Trial name
- EMS-Dialyse (NCT01282554)
- Testing
- electrostimulation program (Rehab 400)
- Where
- 11 sites in France
- Volunteers
- 68 people
- Sponsor
- Rennes University Hospital
Chronic Kidney Failure
Dose Ranging Study of Magnesium Iron Hydroxycarbonate in Haemodialysis Subjects With Hyperphosphataemia
Magnesium iron hydroxycarbonate is a phosphate binder that absorbs phosphate from food, reducing the amount that the body can absorb.
- Trial name
- ACT3 (NCT00436683)
- Testing
- Fermagate, Sevelamer HCl
- Where
- 15 sites in United Kingdom
- Volunteers
- 64 people
- Sponsor
- Ineos Healthcare Limited
End-Stage Renal Disease
Evaluation of a Patient Navigation System to Reduce Time to Waitlisting for Potential Kidney Transplant Recipients
The purpose of this study is to measure the effect of introducing a patient navigator to guide high and moderate risk patients through the pre-waitlisting phases of the kidney transplant process.
- Trial name
- NCT01776073
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- Emory University
End Stage Renal Disease, Peritoneal Dialysis
Comparison of Quality of Life on Automated Peritoneal Dialysis and Continuous Ambulatory Peritoneal Dialysis
The objective of this study is to compare Quality of Life (QoL) between Automated Peritoneal Dialysis (APD) and Continuous Ambulatory Peritoneal Dialysis (CAPD).
- Trial name
- EQlips (NCT01209273)
- Where
- 11 sites in South Korea
- Volunteers
- 260 people
- Sponsor
- Kyungpook National University Hospital
End Stage Renal Disease, Hyperphosphatemia
Phosphate Microvascular Study
Elevated phosphate concentrations in the blood have been associated with multiple negative health outcomes in patients with chronic kidney disease as well as in the general population.
- Trial name
- NCT03594539
- Testing
- Withholding standard phosphate binder
- Volunteers
- 20 people
- Sponsor
- Veterans Medical Research Foundation
Fatigue, End Stage Renal Disease
Fatigue in Chronic Haemodialysis Patients: an Experience Sampling Method Study
To investigate the course and diurnal change of fatigue symptoms and haemodialysis related symptoms in chronic haemodialysis patients, its relation to haemodialysis treatment and the association with other factors by implementing…
- Trial name
- FatHoM (NCT04049773)
- Testing
- haemodialysis
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Zuyderland Medisch Centrum
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