Clinical trials: Renal Failure, End Stage
Heart Failure, Congestive, Kidney Failure, Chronic
N-Acetylcysteine in Heart Failure With Coexistent Chronic Renal Failure
Treatment with n-acetylcysteine in patients with heart failure and chronic renal failure leads to improvements in vascular function and in renal function.
- Trial name
- NCT00532688
- Testing
- N-acetylcysteine
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Bayside Health
End Stage Chronic Renal Failure, Congestive Heart Failure (CHF)
The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular Congestion
The purpose of this study is to evaluate whether a personalized, high-rate fluid removal strategy guided by ultrasound is as safe and effective as the standard fluid removal rate for patients with advanced kidney disease who are…
- Conditions
- End Stage Chronic Renal Failure, Congestive Heart Failure (CHF), Intravascular Congestion, Fluid Overload
- Trial name
- FILTRATE (NCT07705269)
- Testing
- High-rate ultrafiltration, Standard fluid removal
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Calciphylaxis, Calcific Uremic Arteriolopathy
Phase 2 Study With SNF472 in Calciphylaxis Patients
To evaluate the effect of SNF472 on top of standard of care on promoting wound healing and other parameters of therapeutic response in haemodialysis patients with calciphylaxis (calcific uraemic arteriolopathy, CUA).
- Trial name
- NCT02790073
- Testing
- SNF472
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 14 people
- Sponsor
- Sanifit Therapeutics S. A.
End Stage Renal Disease
Elbow Pain in Hemodialysis Patients and Its Effect on Daily Living Activities of the Patients
The study will include the patients undergoing hemodialysis.
- Trial name
- NCT04188210
- Testing
- Presence of elbow pain in patients with end stage renal disease
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Namik Kemal University
Autosomal Dominant Polycystic Kidney Disease
Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease
This study will assess whether everolimus (RAD001) is effective in preventing cyst and kidney expansion as well as worsening of renal function in patients with ADPKD and whether the application of 5 mg/day everolimus as…
- Trial name
- NCT00414440
- Testing
- Everolimus
- Where
- 24 sites in Austria, France and 1 more
- Volunteers
- 431 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Renal Failure
Renal Sympathetic Modification in Patients With Chronic Renal Failure
The purpose of this study is to observe the incident of uremia and dialysis requirement after renal sympathetic modification using THERMOCOOL® catheter in patients with chronic renal failure, and evaluate safety and efficacy of…
- Trial name
- NCT01418560
- Testing
- renal sympathetic modification
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
End Stage Renal Disease
Theranova 400 Dialyzer In End Stage Renal Disease (ESRD) Patients
The study evaluates the efficacy and safety of the Theranova 400 dialyzer compared with Elisio-17 H dialyzer in end stage renal disease patients receiving hemodialysis treatment.
- Trial name
- NCT03257410
- Testing
- Theranova 400 dialyzer, Elisio-17H dialyzer
- Where
- 20 sites in United States
- Volunteers
- 172 people
- Sponsor
- Vantive Health LLC
Kidney Failure, Chronic, Resistance Training
Effect of PT on QL, FC, PWV and Biochemical Markers in CRF on Conservative Treatment
Introduction: Chronic Kidney Disease (CKD) is considered an important public health problem, with prevalence of 9.6% in our population.
- Conditions
- Kidney Failure, Chronic, Resistance Training, Treatment
- Trial name
- NCT01155297
- Testing
- Physical training, Stretching and metabolic exercises
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
End-stage Renal Disease
The Incidence of Extended-spectrum β-lactamase (ESBL) Klebsiella Pneumonia in Patient on Renal Replacement Therapy
The prevalence of ESBL Klebsiella pneumonia was higher in patient with renal replacement therapy.
- Trial name
- NCT01612182
- Testing
- renal replacement therapy
- Where
- South Korea
- Volunteers
- 1,289 people
- Sponsor
- Inje University
Chronic Kidney Disease, End-Stage Renal Disease
House Calls and Decision Support: Improving Access to Live Donor Transplantation
The main purpose of this research program is to reduce the burden of end-stage organ disease on individuals, families, healthcare systems, and society by increasing the availability of donor organs for transplantation.
- Trial name
- NCT01786525
- Testing
- House Calls, Web-Based Patient-Centered Decision Support Intervention
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Beth Israel Deaconess Medical Center
End-Stage Renal Disease
Study of HemoCare™ Hemodialysis System for Home Nocturnal Dialysis in Patients With ESRD
This prospective multi-center, open-label, single-arm study intends to gather and evaluate safety data for the nocturnal use of the HemoCare™ Hemodialysis System.
- Trial name
- NCT04087213
- Testing
- HemoCare™ Hemodialysis System
- Where
- 8 sites in United States
- Volunteers
- 36 people
- Sponsor
- Deka Research and Development
Chronic Kidney Failure
Palm Tocotrienols in Chronic Hemodialysis (Malaysia) (PATCH)
This study aims to determine if tocotrienol rich fraction (TRF) supplementation can improve markers of inflammation, oxidative stress and blood lipids in Malaysian hemodialysis (HD) patients.
- Trial name
- PATCH (NCT02913690)
- Testing
- TRF
- Where
- 4 sites in Malaysia
- Volunteers
- 336 people
- Sponsor
- Wayne State University
Chronic Kidney Disease
Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis
To measure oxycodone's intradialytic mass transfer rate coefficient and oxycodone's removal rate using an ODE/PDE hemodialysis model.
- Trial name
- OCKD (NCT02452437)
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emerio & Lourdes Linares Research and Education Center
End Stage Renal Disease, Cardio-Renal Syndrome
Cardio-Renal Registry
Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality…
- Conditions
- End Stage Renal Disease, Cardio-Renal Syndrome, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- BHCRR (NCT06521801)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 60,000 people
- Sponsor
- Queen Mary University of London
Kidney Disorders
Disparities in National Kidney Allocation Policy
The purpose of the current study is to test a systems-level approach to disseminate a multicomponent, multilevel intervention consisting of educational materials about transplantation and the new kidney allocation system…
- Trial name
- ASCENT (NCT02879812)
- Testing
- Performance Feedback Reports, Educational Video for Staff, Educational Video for Patients
- Where
- 3 sites in United States
- Volunteers
- 56,332 people
- Sponsor
- Emory University
End Stage Renal Disease (ESRD)
Food Preparation Effects on Gut Bacteria in Patients on Peritoneal Dialysis
This is an intervention study of the effects of food preparation on the gut bacteria in patients with end stage renal disease on peritoneal dialysis.
- Trial name
- NCT02467530
- Testing
- AGE
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
End Stage Renal Failure on Dialysis
The Effects of Exercise in End-stage Renal Disease Patients Undergoing Hemodialysis
We aimed to investigate the effect of a progressive resistance training and aerobic training protocol on functional capacity, body composition and quality of life.
- Trial name
- EESRDS (NCT02621918)
- Testing
- Progressive resistance training, Aerobic training
- Volunteers
- 61 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Obstructive Sleep Apnea, End Stage Renal Disease
Effect of Beginning a Renal Replacement Therapy on Obstructive Sleep Apnea in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of beginning a renal replacement therapy on fluid overload and its consequence on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease.
- Trial name
- SASinHD_005 (NCT02073344)
- Testing
- Renal replacement therapy, no intervention
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
End Stage Kidney Disease
The Effect of Intradialytic Exercise on the Functional Capacity of Hemodialysis Patients
The purpose of this study is to explore the impact of an intradialytic exercise program on functional capacity, aerobic capacity, strength, quality of life, depression, hospitalizations and intradialytic episodes of hypotension.
- Trial name
- NCT01877863
- Testing
- exercise
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Kidney Failure, Chronic, Arrhythmias, Cardiac
HOLT-ED: Holter-monitoring in End-stage Renal Disease
The main objective of this prospective cohort study is to assess arrhythmia burden and glycemic variability in a multicenter cohort of patients with end-stage renal disease using a sufficient observation period in order to…
- Conditions
- Kidney Failure, Chronic, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT04876963
- Testing
- Holter-monitor
- Where
- 3 sites in Denmark
- Volunteers
- 268 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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