Clinical trials: Renal Failure, End-stage
Chronic Renal Failure
the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD
To investigate the feasibility of calcium dobesilate in the treatment of microvascular injury provides new ideas and theoretical basis for the prevention and treatment of chronic renal failure.
- Trial name
- NCT03427944
- Testing
- Calcium Dobesilate group, Conventional Treatment group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
End Stage Renal Failure on Dialysis
Nasal Tea Tree Oil for the Prevention of Infections in PD Patients
This study will compare the use of tea tree oil as a topical nasal antiseptic to prevent infections in patients that need renal dialysis.
- Trial name
- NCT01214395
- Testing
- 5% tea tree oil nasal ointment
- Where
- Australia
- Volunteers
- 5 people
- Sponsor
- PathWest Laboratory Medicine WA
Anemia
Comparison of Safety and Efficacy of Intravenous Iron Versus Oral Iron in Chronic Renal Failure Subjects With Anemia
To assess the safety and efficacy of two forms of iron therapy for the treatment of anemia in non-dialysis dependent, chronic renal failure in patients receiving or not receiving erythropoietin.
- Trial name
- NCT00236977
- Testing
- Venofer, Ferrous Sulfate
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- American Regent, Inc.
Chronic Kidney Failure
Identifying Therapeutic Hemodialysis Targets Through Cerebrovascular Reactivity; RESPIRACT 2
Patients with chronic kidney disease receiving hemodialysis (HD) suffer from higher rates of brain vascular disease and decreased cognition than the general population.
- Trial name
- RESPIRACT 2 (NCT05445219)
- Testing
- RespirAct
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Renal Failure
Clinical Study on Optimised Removal of Protein-bound Uremic Toxins With Convective Dialysis Treatment.
Patients will be treated with hemodiafiltration (HDF) in postdilution mode, as a control therapy, during 9 weeks. During week 5 the 1st intervention treatment, predilution hemofiltration (HF) or predilution HDF, will be performed…
- Trial name
- NCT00337831
- Testing
- Performance of predilution hemofiltration, predilution hemodiafiltration or postdilution hemodiafiltration
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- University Hospital, Ghent
End-Stage Renal Disease
Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease
Home palliative care needs are often under-recognized in patients with End-Stage Renal Disease (ESRD). This pilot study is designed to evaluate the effectiveness of referrals to home palliative care services in improving patient…
- Trial name
- SHEPHERD 2 (NCT06144281)
- Testing
- Nudge for PHPC NP Referral
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Pennsylvania
End-Stage Renal Disease Requiring Haemodialysis
Hemodialysis-Induced Renal Perfusion Decline: Unraveling the Pathophysiological Mechanisms Linking Intradialytic Circulatory Stress to Residual Renal Function Loss
Residual renal function (RRF) plays a critical role in quality of life and survival in hemodialysis (HD) patients but characteristically declines after the initiation of HD.
- Trial name
- HD-RPD (NCT07003828)
- Testing
- CEUS examinations
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Yuanjun Yang
End Stage Renal Disease, Hemodiafiltration
To Assess the Effect of HDF Versus High Flux Dialysis on Free Light Chains and Cumulative Albumin Loss, in End Stage Renal Disease Patients.
Removal of uremic toxins is the main goal of HD, It was improved by using high volume convective technique with high flux (HF) dialyzer.
- Conditions
- End Stage Renal Disease, Hemodiafiltration, Hemodialysis
- Trial name
- NCT04747067
- Testing
- BIOPURE 260HF dialyzer
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Ain Shams University
End-stage Renal Disease (ESRD)
Effect of Lifestyle Intervention in Patients With Chronic Kidney Disease on Fitness and Immune Function
To assess the efficacy of a 6-month lifestyle intervention in patients with end-stage renal disease(ESRD), we plan to conduct a self-controlled clinical trial. 34 participants receiving chronic HD will be enrolled.
- Trial name
- NCT05649657
- Testing
- Cyclic aerobic and resistance training
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung Memorial Hospital
Growth Hormone Deficiency, Turner Syndrome
Evaluation of Convenience and Compliance of the Easypod™ Electronic Self-injector
This is an international, multicenter study involving children treated with Saizen®, a growth hormone, who will be trained to use easypod, a new electronic injector and will complete a questionnaire after 12 week of use.
- Conditions
- Growth Hormone Deficiency, Turner Syndrome, Chronic Renal Failure, Small for Gestational Age
- Trial name
- NCT00738205
- Volunteers
- 834 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Kidney Transplantation in Highly Sensitized Patients
Efficacy and Safety in Imlifidase Desensitized Kidney Tx Patients, Including Two Non-Comparative Reference Cohorts
An open-label post authorization efficacy and safety study evaluating graft failure-free survival at 1-year in highly sensitized end-stage renal disease (ESRD) patients with positive crossmatch (XM) against a deceased donor prior…
- Trial name
- PAES (NCT05369975)
- Testing
- Imlifidase, Normal Transplantation Routine
- Where
- 22 sites in Austria, Belgium and 9 more
- Volunteers
- 113 people
- Sponsor
- Hansa Biopharma AB
End-stage Renal Disease, Cardiorenal Syndrome
Cardiorenal Syndrome in End-Stage Kidney Disease
Cardiorenal Syndrome (CRS) is prevalent among end-stage renal disease (ESRD) patients. Recently, its prevalence is rising. There are several different clinical presentations of this syndrome.
- Conditions
- End-stage Renal Disease, Cardiorenal Syndrome, Heart Disease
- Trial name
- NCT02238093
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- Hillel Yaffe Medical Center
End Stage Renal Disease, Nutrition
Endocannabinoids in End Stage Renal Disease
To investigate the relationship between dietary intake, body habitus, and endocannabinoid levels in end stage renal disease patients as compared to matched controls.
- Trial name
- NCT01477515
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Renal Insufficiency, Chronic Kidney Failure
Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE)
The trial is a multicenter, prospective, randomized, open study. A total of 500 elderly patients aged over 75 years with renal insufficiency stage 5 will be included in the study after signed informed consent.
- Conditions
- Chronic Renal Insufficiency, Chronic Kidney Failure, Aged
- Trial name
- BCDE (NCT01225458)
- Testing
- shorter tests, initial complete geriatric tests, follow-up complete geriatric tests
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hyperkalemia, End Stage Renal Disease
Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
The purpose of this study is to determine whether once-daily dosing of patiromer will reduce the frequency of hyperkalemic episodes in ESRD (end stage renal disease) study participants who receive conventional hemodialysis (HD).
- Trial name
- NCT03781089
- Testing
- Patiromer Oral Powder Product
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Duke University
End Stage Renal Failure on Dialysis
Trial of Carbamylation in Renal Disease-Modulation With Amino Acid Therapy
Patients with end stage renal disease (ESRD) usually have high levels of urea that may interact with blood proteins and change their structure by a process known as carbamylation.
- Trial name
- CarRAAT-2 (NCT02472834)
- Testing
- Amino acid supplementation NephrAmine®
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Acute Kidney Injury, End-stage Renal Disease
Hemodynamic Effects of Blood Flow Variation in Continuous Renal Replacement Therapy
Purpose of this study is to evaluate the short-term hemodynamic effects of changes in blood flow rates in critically ill patients receiving continuous renal replacement therapy.
- Trial name
- NCT03078504
- Testing
- continuous renal replacement therapy using System One (TM) setup (Nxstage)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Louis University
End Stage Renal Disease
PMR vs MM for Patients on Hemodialysis
Background: Hemodialysis is considered as an effective therapy to remove harmful waste from the body and to improve the quality of life in patients suffering from end-stage renal disease (ESRD).
- Trial name
- NCT06625125
- Testing
- Mindfulness-based intervention, Progressive muscle relaxation
- Where
- Jordan
- Volunteers
- 159 people
- Sponsor
- Jordan University of Science and Technology
Vitamin D Deficiency, Vascular Calcification
Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Aim: To investigate whether cholecalciferol (4800 U/daily) or placebo for 16 weeks reduces proteins levels associated with vascular calcification (osteoprotegerin, osteopontin, osteocalcin) in patients treated with peritoneal…
- Conditions
- Vitamin D Deficiency, Vascular Calcification, Renal Insufficiency, End Stage Renal Failure on Dialysis
- Trial name
- NCT02598635
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
End Stage Renal Disease
A Study to Investigate the Influence of PTH-lowering by Etelcalcetide (Parsabiv®) on the Calcification Propensity of Serum in Dialysis Patients
This is a single-center, prospective, dose-escalation, pilot study in 15 end-stage renal disease patients on chronic hemodialysis with secondary hyperparathyroidism.
- Trial name
- NCT03795558
- Testing
- Etelcalcetide
- Where
- Austria
- Volunteers
- 37 people
- Sponsor
- Prim. Priv. Doz. Dr. Daniel Cejka
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