Clinical trials: Renal Failure Chronic Contrast Induced
Diabetes, Chronic Kidney Insufficiency
Prevention of Contrast Induced Nephropathy by Erythropoietin
This ia a prospective, randomized, double blind, placebo controlled trial. patients schedule for primary PCI or elective PCI will randomly allocated to receive either a single dose of EPO (Recormon, Roche, Epoetin beta) or saline…
- Trial name
- NCT01364402
- Testing
- Epoetin beta, Saline 0.9%
- Where
- Israel
- Volunteers
- 142 people
- Sponsor
- Western Galilee Hospital-Nahariya
Chronic Kidney Disease
The Prevention of Contrast Induced Nephropathy by Sarpogrelate in Patients With Chronic Kidney Disease
Background: Contrast-induced nephropathy (CIN) is a serious clinical problem associated with increased morbidity and mortality, particularly in patients with chronic renal insufficiency.
- Trial name
- NCT01165567
- Testing
- sarpogrelate
- Where
- South Korea
- Volunteers
- 212 people
- Sponsor
- Seoul National University Boramae Hospital
Kidney Failure, Acute, Contrast Media
Bicarbonate v Saline to Prevent Contrast Nephropathy
Slowing of kidney function occurs in a minority of people given dye during angiography. The purpose of this study is to compare two different types of fluid given into a vein to reduce the risk of kidney injury: salt in water or…
- Trial name
- NCT00384995
- Testing
- 0.9% (154 mEq/L) IV Sodium Chloride, 1/6 M (166 mEq/L) IV Sodium Bicarbonate
- Where
- 5 sites in Italy
- Volunteers
- 61 people
- Sponsor
- Italian Society of Nephrology
Radiocontrast-induced Nephropathy
Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material
Millions of people receive radiographic contrast material for investigations like CT and coronary angiography. While considered safe in healthy patients, it can cause acute renal impairment.
- Trial name
- NCT00558142
- Testing
- Acetylcysteine, Visipaque 320
- Where
- United Kingdom
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Chronic Renal Insufficiency, Coronary Angiography
Contrast-medium Induced Nephrotoxicity in Patients Undergoing Coronary Angiography - Iodixanol Versus Iopromide
In the treatment of coronary heart disease which is the major cause of heart attack, direct mechanical treatment with catheters such as the coronary angiography, coronary balloon intervention and stenting intervention are the…
- Trial name
- NCT00823628
- Testing
- contrast agent (iopromide), contrast agent (iodixanol)
- Where
- South Korea
- Volunteers
- 420 people
- Sponsor
- Seoul National University Bundang Hospital
Coronary Artery Disease, Chronic Kidney Diseases
IVUS Guided PCI for CKD to Reduce CI-AKI
Patients with Chronic kidney disease are most vulnerable to contrast induced nephropathy after Percutaneous coronary intervention, intravascular ultrasound guidance can be used to safely guide the procedure to reduce the contrast…
- Trial name
- IVUS-CKD (NCT05913362)
- Testing
- IVUS based ultralow contrast PCI
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Jilin University
Renal Failure Chronic Contrast Induced
Effect of a Pre-interventional Diet on Renal Function After Administration of Contrast Agent in Patients at Risk
The aim of this study is to assess the effect of a diet prior to administration of contrast agent in terms of a preventive procedure which leads to an attenuation of the contrast-induced nephropathy (CIN).
- Trial name
- CR_KMN (NCT01879839)
- Testing
- Diet
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Cologne
Acute Kidney Injury
Effect of Darbepoetin in Contrast-induced Nephropathy
The purpose of this study is to determine whether the drug that produce red blood cells is effective in the prevention of kidney dysfunction after coronary angiography in patients with chronic kidney disease.
- Trial name
- NCT01197235
- Testing
- darbepoetin-α, isotonic saline
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Contrast Induced Nephropathy
Efficacy of Alpha Tocopherol for Prevention of Contrast-induced Nephropathy in Chronic Kidney Disease (CKD) Patients
The purpose of this study is to demonstrate the efficacy of alpha tocopherol for prevention contrast-induced nephropathy in CKD patients undergoing elective coronary procedures.
- Trial name
- NCT01061320
- Testing
- alpha tocopherol
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Thammasat University
Acute Kidney Injury, Contrast Media Toxicity
Curcuminoids and Contrast-induced Acute Kidney Injury
The objective of this study was to evaluate the role of curcuminoids in the prevention of CI-AKI in CKD patients.The result of the study was prophylactic administration with curcuminoids in addition to standard treatment reduce…
- Conditions
- Acute Kidney Injury, Contrast Media Toxicity, Curcuminoid, Chronic Kidney Diseases
- Trial name
- NCT04890704
- Testing
- Curcuminoid
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Kidney Diseases, Diabetes Mellitus
Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy
The aim of this prospective, randomized, controlled study is to investigate the effect of pretreatment with intravenous Alprostadil on the incidence of CIN in a high-risk population of patients with both type 2 diabetes mellitus…
- Conditions
- Kidney Diseases, Diabetes Mellitus, Acute Kidney Injury, Kidney Failure, Chronic
- Trial name
- NCT01722513
- Testing
- Alprostadil ﹠control
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Diabetes Mellitus, Chronic Kidney Disease
Berberine Prevent Contrast-induced Nephropathy in Patients With Diabetes
The number of cardiac angiography and percutaneous coronary interventions (PCI) has increased steadily in recent years. This has resulted in the increasing incidence of contrast-induced nephropathy (CIN).
- Trial name
- NCT02808351
- Testing
- Berberine
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Contrast-induced Nephropathy, Chronic Kidney Diseases
Multi-Center Trial Utilizing Low Frequency Ultrasound in the Prevention of Post-Contrast Acute Kidney Injury
Multi-center randomized trial to assess the safety and performance of low-frequency therapeutic ultrasound for maintaining renal function after contrast exposure.
- Trial name
- LOTUS (NCT04877847)
- Testing
- Low-frequency therapeutic ultrasound (LOTUS), LOTUS System with Ultrasound Disabled
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Sonogenix
Acute Kidney Injury, Renal Insufficiency, Chronic
Safety of Iodinated Contrast in Liver Transplant Candidates With Decreased Renal Function Undergoing Coronary CT Angiography
This study evaluates the safety of iodinated contrast medium administered to liver transplant candidates with decreased renal function undergoing coronary CT angiography.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Chronic, Contrast-induced Nephropathy, Liver Transplantation
- Trial name
- NCT03806725
- Testing
- Intravenous administration of iodinated contrast medium for coronary CT angiography
- Where
- United States
- Sponsor
- Stanford University
Contrast Induced Nephropathy
Statins for Prevention of Contrast Induced Nephropathy
In this randomized study the investigators wish to explore the role of pre-procedural statin therapy for the prevention of contrast induced nephropathy in patients with moderate-to-severe renal dysfunction, submitted to elective…
- Trial name
- NCT00770796
- Testing
- Atorvastatin
- Volunteers
- 304 people
- Sponsor
- Ospedale Misericordia e Dolce
Chronic Renal Insufficiency, Diabete Mellitus
Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure
To evaluate cardio-renal and overall safety profile of GE 145 320 mg I/ml Injection when compared to iopamidol 370 mg I/mL. The study will focus on elderly subjects with either chronic renal insufficiency, or diabetes mellitus…
- Conditions
- Chronic Renal Insufficiency, Diabete Mellitus, Congestive Heart Failure
- Trial name
- NCT01252810
- Testing
- GE-145
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- GE Healthcare
Renal Insufficiency, Chronic, Angioplasty, Transluminal, Percutaneous Coronary
Iodixanol vs. Iomeprol to Prevent Contrast-Induced Nephropathy After Coronary Intervention (CONTRAST)
The purpose of this study is to demonstrate that Iodixanol 320 is associated with a lower incidence of contrast-induced nephropathy (CIN) when compared with hyperosmolar contrast medium Iomeprol 350 in patients with impaired…
- Conditions
- Renal Insufficiency, Chronic, Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis
- Trial name
- NCT00390585
- Testing
- Iodixanol 320, Iomeprol 350
- Where
- 2 sites in Germany
- Volunteers
- 324 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Pentoxifylline, Contrast Induced Nephropathy
Pentoxifylline for Prevention of Contrast Induced Nephropathy in Chronic Kidney Diseased Patients in Intensive Care Unit
The aim of this study is to evaluate the effect of pentoxifylline for control of contrast induced nephropathy in chronic kidney diseased patients in intensive care unit.
- Conditions
- Pentoxifylline, Contrast Induced Nephropathy, Chronic Kidney Disease, Intensive Care Unit
- Trial name
- NCT07561801
- Testing
- Pentoxifylline, Normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Acute Kidney Injury, Acute Renal Failure
Post-Market Observation Study of Intra-renal Drug Delivery (PROVIDE)
This is a prospective, observational, multi-center study with consecutive enrollment. Up to 500 patients will be enrolled. All (consecutive) adult patients in whom one or more components of the Benephit Infusion System are…
- Conditions
- Acute Kidney Injury, Acute Renal Failure, Renal Failure Chronic Contrast Induced, Chronic Kidney Disease
- Trial name
- PROVIDE (NCT01064895)
- Testing
- Benephit catheter for Targeted Renal Therapy
- Where
- 15 sites in United States
- Sponsor
- Angiodynamics, Inc.
Contrast Induced Nephropathy
PREdictive Value of COntrast voluMe to creatinINe Clearance Ratio
To determine a relatively safe contrast media volume to creatinine clearance cut-off value to avoid contrast-induced nephropathy in patients following coronary angiography
- Trial name
- PRECOMIN (NCT01400295)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Guangdong Provincial People's Hospital